Originally published in 2012, revised edition published in 2013, by Fourth Estate, Great Britain; Published in the United States in 2012, revised edition also, by Faber and Faber, Inc.

A NEW YORK TIMES BESTSELLER * New York Times Notable Book * Best Book of the Year: New York Public Library, Kirkus Reviews, Science Friday With a new postscript by the author From an award-winning journalist, an explosive narrative investigation of the generic drug boom that reveals fraud and life-threatening dangers on a global scale—The Jungle for pharmaceuticals Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true? Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects. The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

We take our medicines on faith. We assume our doctors are well-informed, our drug companies scrupulous, our FDA diligent—and our medications safe. All too often we're wrong. Just how wrong is documented in this critically acclaimed portrait of the international pharmaceutical industry by one of our most highly respected investigative journalists. According to the Journal of the American Medical Association (JAMA), adverse drug reactions are the fourth leading cause of death in America. Reactions to prescription and over-the-counter medications kill far more people annually than all illegal drug use combined. Stephen Fried's wife took a pill for a minor infection—and ended up in the emergency room. Some drug reactions go away in a few hours or days. Diane's did not. This emotionally wrenching experience launched Fried into a five-year examination of the entire pharmaceutical industry, the most profitable legal business in the world. Rigorously documented, Bitter Pills is a full-scale portrait of pill making and pill taking in America today, presented through the powerful human drama of doctors, patients, drug companies, the FDA, and government regulators as they war for control of our medicine cabinets.

A veteran board-certified pharmacist cites the high number of annual deaths associated with prescription drug side effects, calling for changes in prescription practices that account for the needs of aging bodies.

The frustration of watching for over 20 years as rip offs disguised under a prescription label went out the pharmacy door has built up like lava under Krakatoa and I'm finally calling it.... Pharmaceutical manufacturers never hesitate to tell you prescription prices are so high because of the staggering costs involved in researching and developing new medicines. The truth is though, that while it does cost big bucks to bring a truly innovative product to market, pharmacy shelves are also stocked with blatant rip offs. Tiny manipulations of prescription strengths that make them no more effective but incredibly more expensive. Combination pills of meds that have been available separately for years treated as if they were a new product. A topical foam that contains the same product as a cream but is priced over a hundred dollars more. A glaucoma medicine that is repackaged with a little brush and sold, for more money, as an eyelash thickener. Even, in some cases, medicines that are less effective or even more dangerous than cheaper alternatives, but are promoted as the next new breakthrough. My plan with this book is to help empower you to become a smarter health care consumer by arming you with facts the pharmaceutical industry doesn't want you to know. Remember, your goal as a patient is to get better, while the goal of the drug company is to collect each and every last dollar it can. Sometimes those goals coincide, but many times they do not, so it can pay handsomely to do some research before getting that prescription filled. I wrote this book to give you an idea what could be at stake. Good luck.

This book is about the powerful, sometimes lifesaving, yet sometimes highly destructive antibiotics known as fluoroquinolones. Best known of these drugs are Cipro (ciprofloxacin) and Levaquin (levofloxacin), as well as four others. This book, How We Can Halt the Cipro and Levaquin Catastrophe: the Worst Medication Disaster in U.S. History, has two main goals. The first goal is to alert patients and doctors of the truly destructive capability of these drugs to cause serious, sometimes long term, sometimes permanent injuries. The capacity of these drugs for such damage has been attested by the U.S. Food and Drug Administration and others many times and is by now incontrovertible. Hundreds of patients, many of whom are quoted in this book, have confirmed their long-lasting injuries to me, while many hundreds more have been ignored or dismissed by their doctors. This must stop. Ignoring these problems has only made the problem worse. My second goal in writing How We Can Halt the Cipro and Levaquin Catastrophe: the Worst Medication Disaster in U.S. History is to stimulate the interest of government, the drug industry, medical institutions and all others for any and all ideas regarding remedies, solutions, and any other ideas that may help end the suffering experienced by patients with the Fluoroquinolone Toxicity Syndrome that can affect many human systems including the musculoskeletal, nervous, psychiatric, gastrointestinal, and others. As you will see, I have offered some ideas for therapies that may provide benefit to some of the injured. I think it is imperative that we follow a trail that may lead us to an understanding of how these drugs work and particularly how they injure, and most of all how we might help people heal, obtain pain reduction and hope. Thousands of lives, young and old, depend on the efforts that we make.

An exploration of drug counterfeiting activities in America traces a drug theft investigation in Florida with ties to a national network of drug polluters and the government, exposing how political interests may be compromising the integrity of the nation's medical distribution system. Reprint. 30,000 first printing.