How the extraordinary multisensory phenomenon of synesthesia has changed our traditional view of the brain.

Revealing the neuroscience and genetics behind synesthesia—and how this multi-sensory phenomenon changed our view of the brain. A person with synesthesia might feel the flavor of food on her fingertips, sense the letter “J” as shimmering magenta or the number “5” as emerald green, hear and taste her husband’s voice as buttery golden brown. Synesthetes rarely talk about their peculiar sensory gift—believing either that everyone else senses the world exactly as they do, or that no one else does. Yet synesthesia occurs in 1 in 20 people, and is even more common among artists. One famous synesthete was novelist Vladimir Nabokov, who insisted as a toddler that the colors on his wooden alphabet blocks were “all wrong.” His mother understood exactly what he meant because she, too, had synesthesia. Nabokov's son Dmitri, who recounts this tale in the afterword to this book, is also a synesthete—further illustrating how synesthesia runs in families. Wednesday Is Indigo Blue reveals how the extraordinary multisensory phenomenon of synesthesia has changed our traditional view of the brain. Because synesthesia contradicted existing theory, researcher Richard Cytowic spent 20 years persuading colleagues that it was a real—and important—brain phenomenon rather than a mere curiosity. Today, scientists in 15 countries are exploring synesthesia and how it is changing the traditional view of how the brain works. Cytowic and neuroscientist David Eagleman argue that perception is already multisensory, though for most of us its multiple dimensions exist beyond the reach of consciousness. Reality, they point out, is more subjective than most people realize. No mere curiosity, synesthesia is a window on the mind and brain, highlighting the amazing differences in the way people see the world.

In this medical detective adventure, Cytowic shows how synesthesia, or "joined sensation," illuminates a wide swath of mental life and leads to a new view of what it means to be human. Richard Cytowic's dinner host apologized, "There aren't enough points on the chicken!" He felt flavor also as a physical shape in his hands, and the chicken had come out "too round." This offbeat comment in 1980 launched Cytowic's exploration into the oddity called synesthesia. He is one of the few world authorities on the subject. Sharing a root with anesthesia ("no sensation"), synesthesia means "joined sensation," whereby a voice, for example, is not only heard but also seen, felt, or tasted. The trait is involuntary, hereditary, and fairly common. It stayed a scientific mystery for two centuries until Cytowic's original experiments led to a neurological explanation—and to a new concept of brain organization that accentuates emotion over reason. That chicken dinner two decades ago led Cytowic to explore a deeper reality that, he argues, exists in everyone but is often just below the surface of awareness (which is why finding meaning in our lives can be elusive). In this medical detective adventure, Cytowic shows how synesthesia, far from being a mere curiosity, illuminates a wide swath of mental life and leads to a new view of what is means to be human—a view that turns upside down conventional ideas about reason, emotional knowledge, and self-understanding. This 2003 edition features a new afterword.

Synesthesia comes from the Greek syn (meaning union) and aisthesis (sensation), literally interpreted as a joining of the senses. Synesthesia is an involuntary joining in which the real information from one sense is joined or accompanies a perception in another. Dr. Cytowic reports extensive research into the physical, psychological, neural, and familial background of a group of synesthets. His findings form the first complete picture of the brain mechanisms that underlie this remarkable perceptual experience. His research demonstrates that this rare condition is brain-based and perceptual and not mind-based, as is the case with memory or imagery. Synesthesia offers a unique and detailed study of a condition which has confounded scientists for more than 200 years.

"Eagleman renders the secrets of the brain’s adaptability into a truly compelling page-turner.” —Khaled Hosseini, author of The Kite Runner “Livewired reads wonderfully like what a book would be if it were written by Oliver Sacks and William Gibson, sitting on Carl Sagan’s front lawn.” —The Wall Street Journal What does drug withdrawal have in common with a broken heart? Why is the enemy of memory not time but other memories? How can a blind person learn to see with her tongue, or a deaf person learn to hear with his skin? Why did many people in the 1980s mistakenly perceive book pages to be slightly red in color? Why is the world’s best archer armless? Might we someday control a robot with our thoughts, just as we do our fingers and toes? Why do we dream at night, and what does that have to do with the rotation of the Earth? The answers to these questions are right behind our eyes. The greatest technology we have ever discovered on our planet is the three-pound organ carried in the vault of the skull. This book is not simply about what the brain is; it is about what it does. The magic of the brain is not found in the parts it’s made of but in the way those parts unceasingly reweave themselves in an electric, living fabric. In Livewired, you will surf the leading edge of neuroscience atop the anecdotes and metaphors that have made David Eagleman one of the best scientific translators of our generation. Covering decades of research to the present day, Livewired also presents new discoveries from Eagleman’s own laboratory, from synesthesia to dreaming to wearable neurotech devices that revolutionize how we think about the senses.

Indigo is the rich, electrifying history of a precious dye: its relationship to the trans-Atlantic slave trade, its profound influence on fashion, and its spiritual significance - all very much alive today. But it is also the story of a personal quest: Catherine McKinley's ancestors include a clan of Scots who wore indigo tartan, several generations of Jewish 'rag traders' and Massachusetts textile factory owners, and African slaves who were traded along the same Saharan routes as indigo. Her journey takes her to nine West African countries and is resplendent with powerful lessons of heritage and history which shape the way she understands her world at home.

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