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This book is open access under a CC BY 4.0 license. This book explores the social history of the anti-vivisection movement in Britain from its nineteenth-century beginnings until the 1960s. It discusses the ethical principles that inspired the movement and the socio-political background that explains its rise and fall. Opposition to vivisection began when medical practitioners complained it was contrary to the compassionate ethos of their profession. Christian anti-cruelty organizations took up the cause out of concern that callousness among the professional classes would have a demoralizing effect on the rest of society. As the nineteenth century drew to a close, the influence of transcendentalism, Eastern religions and the spiritual revival led new age social reformers to champion a more holistic approach to science, and dismiss reliance on vivisection as a materialistic oversimplification. In response, scientists claimed it was necessary to remain objective and unemotional in order to perform the experiments necessary for medical progress.

Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.

Book flips to highlight two differing perspectives of the issue.

Ethical questions about the use of animals and humans in research remain among the most vexing within both the scientific community and society at large. These often rancorous arguments have gone on, however, with little awareness of their historical antecedents. Experimentation on animals and particularly humans is often assumed to be a uniquely modern phenomenon, but the ideas and attitudes that encourage the biological and medical sciences to experiment on living creatures date from the earliest expression of Western thought. Here, Anita Guerrini looks at the history of these practices from vivisection in ancient Alexandria to present-day battles over animal rights and medical research employing human subjects. Guerrini discusses key historical episodes, including the discovery of blood circulation, the development of smallpox and polio vaccines, and recent AIDS research. She also explores the rise of the antivivisection movement in Victorian England, the modern animal rights movement, and current debates over gene therapy.--From publisher description.

Susan Lederer provides the first full-length history of early biomedical research with human subjects. Lederer offers detailed accounts of experiments conducted on both healthy and unhealthy men, women, and children, during the period from 1890 to 1940, including yellow fever experiments, Udo Wile's "dental drill" experiments on insane patients, and Hideyo Noguchi's syphilis experiments.