Virus Hunt is a tale of scientific endeavour. Tracing the fascinating twenty year quest to find the origin of the virus that causes AIDS, Dorothy H. Crawford takes us on a journey around the world, to recount the vital research that eventually unravelled how, when, and where the virus first infected humans.

About 375 million people are infected with the hepatitis B virus. It has killed more people than AIDS and also causes millions of cases of liver cancer. The discovery of this deadly virus and the vaccine against it--a vaccine that is sharply decreasing the infection rate worldwide and is probably the first effective cancer vaccine--was one of the great triumphs of twentieth-century medicine. And it almost didn't happen. With wit and insight, this scientific memoir and story of discovery describes how Baruch Blumberg and a team of researchers found a virus they were not looking for and created a vaccine for a disease they previously knew little about--work that took the author around the world and won him the Nobel Prize. Blumberg and his collaborators were investigating relationships between gene distribution and disease susceptibility, research that was yielding interesting data but no real breakthroughs. Many viewed their work as more field trip than science. But, through decades of hard work and investigative twists and turns, their pursuit led to the hepatitis B antigen, the elusive virus itself, and, ultimately, the vaccine. As he takes the reader through the detective work that culminated in his incredible discovery, the author recounts with immediacy exciting moments in the lab and in the field--from a hair-raising flight to Africa to an unpleasant encounter with Alaskan sled dogs. The hepatitis B story is more than a fascinating chronicle of a major discovery. What Blumberg followed to the virus was a trail of remarkable "accidents" that happen when scientists seek answers to interesting questions. Those events, combined with the investigator's determined persistence, resulted in studies that generated a pharmaceutical industry, have far-flung public-health applications, and saved millions of lives.

Is cancer a contagious disease? In the late nineteenth century this idea, and attending efforts to identify a cancer “germ,” inspired fear and ignited controversy. Yet speculation that cancer might be contagious also contained a kernel of hope that the strategies used against infectious diseases, especially vaccination, might be able to subdue this dread disease. Today, nearly one in six cancers are thought to have an infectious cause, but the path to that understanding was twisting and turbulent. ​ A Contagious Cause is the first book to trace the century-long hunt for a human cancer virus in America, an effort whose scale exceeded that of the Human Genome Project. The government’s campaign merged the worlds of molecular biology, public health, and military planning in the name of translating laboratory discoveries into useful medical therapies. However, its expansion into biomedical research sparked fierce conflict. Many biologists dismissed the suggestion that research should be planned and the idea of curing cancer by a vaccine or any other means as unrealistic, if not dangerous. Although the American hunt was ultimately fruitless, this effort nonetheless profoundly shaped our understanding of life at its most fundamental levels. A Contagious Cause links laboratory and legislature as has rarely been done before, creating a new chapter in the histories of science and American politics.

On the 100th anniversary of the pandemic of 1918, Jeremy Brown, veteran ER doctor and Director of Emergency Care Research at the National Institutes of Health, explores the troubling and complex history of the flu virus. He breaks down the current dialogue about the disease, explaining the controversy over vaccinations, antiviral drugs, and the federal government's role in preparing for pandemic outbreaks. Influenza is an enlightening and unnerving look at a deadly virus that has been around longer than people and may be for many more years before we are able to conquer it for good.

In 1918 the Spanish flu epidemic swept the world and killed an estimated 20 to 40 million people in just one year, more than the number that died during the four years of the First World War. To this day medical science has been at a loss to explain the Spanish flu's origin. Most virologists are convinced that sooner or later a similarly deadly flu virus will return with a vengeance; thus anything we can learn from the 1918 flu may save lives in a new epidemic. Responding to sustained interest in this medical mystery, Hunting the 1918 Flu presents a detailed account of Kirsty Duncan's experiences as she organized an international, multi-discipline scientific expedition to exhume the bodies of a group of Norwegian miners buried in Svalbard, all victims of the flu virus. Constant throughout is her determination to honour the Norwegian laws and the Svalbard customs that treat the dead and the living with respect - especially when a live virus, if unearthed, could kill millions. Another theme of the book is the author's growing love for Svalbard and its people. Duncan's narrative describes a large-scale medical project to uncover genetic material from the Spanish flu; it also reveals the turbulent politics of a group moving towards a goal where the egos were as strong as the stakes were high. The author, herself a medical geographer, is very frank about her bruising emotional, financial, and professional experiences on the 'dark side of science.' Duncan raises questions not only about public health, epidemiology, the ethics of science, and the rights of subjects, but also about the role of age, gender, and privilege in science. While her search for the virus has shown promising results, it has also revealed the dangers of science itself being subsumed in the rush for personal acclaim.

After experiencing the SARS outbreak in 2003, Hong Kong, Singapore, and Taiwan all invested in various techniques to mitigate future pandemics involving myriad cross-species interactions between humans and birds. In some locations microbiologists allied with veterinarians and birdwatchers to follow the mutations of flu viruses in birds and humans and create preparedness strategies, while in others, public health officials worked toward preventing pandemics by killing thousands of birds. In Avian Reservoirs Frédéric Keck offers a comparative analysis of these responses, tracing how the anticipation of bird flu pandemics has changed relations between birds and humans in China. Drawing on anthropological theory and ethnographic fieldwork, Keck demonstrates that varied strategies dealing with the threat of pandemics—stockpiling vaccines and samples in Taiwan, simulating pandemics in Singapore, and monitoring viruses and disease vectors in Hong Kong—reflect local geopolitical relations to mainland China. In outlining how interactions among pathogens, birds, and humans shape the way people imagine future pandemics, Keck illuminates how interspecies relations are crucial for protecting against such threats.

A New York Times Notable Book The man who led the battle against Ebola in The Hot Zone teams up with the bestselling co-author of Mind Hunter to chronicle his extraordinary thirty-year career fighting deadly viruses. For three decades, Dr. C. J. Peters was on the front lines of our biological battle against “hot” viruses around the world. In the course of that career, he learned countless lessons about our interspecies turf wars with infectious agents. Called in to contain an outbreak of deadly hemorrhagic fever in Bolivia, he confronted the despair of trying to save a colleague who accidentally infected himself with an errant scalpel. Working in Level 4 labs on the Machupo and Ebola viruses, he saw time and again why expensive high-tech biohazard containment equipment is only as safe as the people who use it. Because of new, emerging viruses, and the return of old, “vanquished” ones for which vaccines do not exist, there remains a very real danger of a new epidemic that could, without proper surveillance and early intervention, spread worldwide virtually overnight. And the possibility of foreign countries or terrorist groups using deadly airborne viruses—the poor man’s nuclear arsenal—looms larger than ever. High-octane science writing at its best and most revealing, Virus Hunter is a thrilling first-person account of what it is like to be a warrior in the Hot Zone.