Antimicrobial Stewardship (AMS), Volume Two includes the experience of ESGAP workshops and courses on antibiotic stewardship since 2012. It combines clinical and laboratory information about AMS, with a focus on human medicine. The ESCMID study group on antibiotic policies (ESGAP) is one of the most productive groups in the field, organizing courses and workshops. This book is an ideal tool for the participants of these workshops. With short chapters (around 1500 words) written on different topics, the authors insisted on the following points: A 'hands on', practical approach, tips to increase success, a description of the most common mistakes, a global picture (out- and inpatient settings, all countries) and a short list of 10-20 landmark references. - Focuses on the most recent antimicrobial stewardship strategies - Provides a detailed description of laboratory support - Offers a balanced synthesis of basic and clinical sciences for each individual case, presenting clinical courses of the cases in parallel with the pathogenesis and detailed microbiological information for each infection - Describes the prevalence and incidence of the global issues and current therapeutic approaches - Presents the measures for infection control

This book approaches the topic of management of acute ischemic stroke in an interdisciplinary manner, explaining how best to utilize the methods currently available for medical, surgical, and endovascular care. After an opening section on basics such as pathophysiology, radiological assessment, and pathology, comprehensive and up-to-date information is provided on each of the available therapies, techniques, and practices. Special attention is paid to recent advances in neurointerventional and neurosurgical procedures, with clear description of important technical details.The book includes plentiful high-quality case illustrations and a wealth of practical information that will prove of value in emergency rooms, angiography suites, operating rooms, and intensive care units. It will aid not only neurologists, neurointerventionists, and neurosurgeons, but also all others who are involved in the management of acute ischemic stroke, from radiologists and emergency physicians to healthcare providers.

Based on the classic sci-fi series Doomwatch, Mutant 59 imagines one of the most terrifying tragedies that modern science could create, a chilling and topical story of what happens when scientific research goes wrong and spreads terror through London (and endangers the world). When an airplane crashes the Ministry of Transport investigates, what caused it to fall out of the sky and could it happen again? Slowly they discover that science has unleashed a genetically engineered bacteria that feeds on (and destroys) all plastic materials. No-one takes any notice of the material used to build gas pipes, electrical insulation, cars and planes until it begins to disintegrate and explode. Has science created a biological time bomb? A jet plane crashes near Heathrow, in the Atlantic a nuclear submarine disappears without trace, central London grinds to a halt. As power stations explode and London's population is evacuated Anna Kramer and Luke Gerrard search for the scientific key to a fiery holocaust that is capable of infecting the world.

War is humanity’s only hope. “Aldiss’ dark vision of collapsing society and withering earth is poignant and brutal . . . [a] richly detailed world” (Science Fiction Ruminations). In a future where the Earth has been savaged by overpopulation and over‐farming, robots are considered more valuable than humans and sand must be altered to create artificially fertile soil. Ex‐convict Knowle Noland, the hallucinating sea captain of the Trieste Star, finds himself wrapped up in a plot to incite a global war that will wipe out millions. War, it seems, is the only way to drastically reduce the population and create a better world for those who survive.

?The female of the species vanished on the afternoon of the second Tuesday of Februaryøat four minutes and fifty-two seconds past four o'clock, Eastern Standard Time. The event occurred universally at the same instant, without regard to time belts, and was followed by such phenomena as might be expected after happenings of that nature.? ø On a lazy, quiet afternoon, in the blink of an eye, our world shatters into two parallel universes as men vanish from women and women from men. After families and loved ones separate from one another, life continues in very different ways for men and women, boys and girls. An explosion of violence sweeps one world that still operates technologically; social stability and peace in the other are offset by famine and a widespread breakdown in machinery and science. And as we learn from the fascinating parallel stories of a brilliant couple, Bill and Paula Gaunt, the foundations of relationships, love, and sex are scrutinized, tested, and sometimes redefined in both worlds. The radically divergent trajectories of the gendered histories reveal stark truths about the rigidly defined expectations placed on men and women and their sexual relationships and make clear how much society depends on interconnection between the sexes. ø Written over a half century ago yet brimming with insight and unsettling in its relevance today, The Disappearance is a masterpiece of modern speculative fiction.

When A.E. van Vogt wove several of his classic stories of The Rull into a novel, he created a work of enduring popularity in the science fiction field. Now back in print for the first time in the 1990s, this Tor edition includes "The First Rull," a story that postdates the novel and makes this book the first complete edition of the saga of the war between humanity and the alien shapechangers.

The classic novel of non-Aristotelian logic and the coming race of supermen Grandmaster A. E. van Vogt was one of the giants of the 1940s, the Golden Age of classic SF. Of his masterpieces, The World of Null-A is his most famous and most influential. It was the first major trade SF hardcover ever, in 1949, and has been in print in various editions ever since. The entire careers of Philip K. Dick, Keith Laumer, Alfred Bester, Charles Harness, and Philip Jose Farmer were created or influenced by The World of Null-A, and so it is required reading for anyone who wishes to know the canon of SF classics. It is the year 2650 and Earth has become a world of non-Aristotelianism, or Null-A. This is the story of Gilbert Gosseyn, who lives in that future world where the Games Machine, made up of twenty-five thousand electronic brains, sets the course of people's lives. Gosseyn isn't even sure of his own identity, but realizes he has some remarkable abilities and sets out to use them to discover who has made him a pawn in an interstellar plot. At the Publisher's request, this title is being sold without Digital Rights Management Software (DRM) applied.