Validation and Regulatory Acceptance of Toxicological Test Methods
Title | Validation and Regulatory Acceptance of Toxicological Test Methods PDF eBook |
Author | DIANE Publishing Company |
Publisher | DIANE Publishing |
Pages | 95 |
Release | 1998-02 |
Genre | |
ISBN | 0788142321 |
Validation and Regulatory Acceptance of Toxicological Test Methods
Title | Validation and Regulatory Acceptance of Toxicological Test Methods PDF eBook |
Author | |
Publisher | |
Pages | 130 |
Release | 1997 |
Genre | Toxicity testing |
ISBN |
Validation and Regulatory Acceptance of Toxicological Test Methods
Title | Validation and Regulatory Acceptance of Toxicological Test Methods PDF eBook |
Author | Errol Zeiger |
Publisher | |
Pages | 105 |
Release | 1998-04 |
Genre | |
ISBN | 9780788148552 |
This report was developed to recommend criteria & processes for validation & regulatory acceptance of toxicological testing methods that would be useful to Federal agencies & the scientific community. The specific goals of the report include: communicating the criteria & procedures to employ in considering new & revised test methods; encouraging the development, validation, & evaluation of new & revised test methods; contributing to regulatory acceptance & encouraging the use of valid new & revised test methods, & encouraging the reduction & refinement of animal use in testing.
Validation of Alternative Methods for Toxicity Testing
Title | Validation of Alternative Methods for Toxicity Testing PDF eBook |
Author | Chantra Eskes |
Publisher | Springer |
Pages | 418 |
Release | 2016-09-26 |
Genre | Medical |
ISBN | 3319338269 |
This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and transcriptomics, and for methods derived from pathway-based concepts in toxicology. Validation of Alternative Methods for Toxicity Testing is divided into two sections, in the first, practical insights are given on the state-of-the-art and on approaches that have resulted in successfully validated and accepted alternative methods. The second section focuses on the evolution of validation principles and practice that are necessary to ensure fit-for-purpose validation that has the greatest impact on international regulatory acceptance of alternative methods. In this context validation needs to keep pace with the considerable scientific advancements being made in toxicology, the availability of sophisticated tools and techniques that can be applied in a variety of ways, and the increasing societal and regulatory demands for better safety assessment. This book will be a useful resource for scientists in the field of toxicology, both from industry and academia, developing new test methods, strategies or techniques, as well as Governmental and regulatory authorities interested in understanding the principles and practicalities of validation of alternative methods for toxicity testing.
Validation and Regulatory Acceptance of Toxicological Test Methods
Title | Validation and Regulatory Acceptance of Toxicological Test Methods PDF eBook |
Author | Interagency Coordination Committee on the Validation of Alternative Methods |
Publisher | |
Pages | 85 |
Release | 1995 |
Genre | |
ISBN |
NTP Workshop on Validation and Regulatory Acceptance of Alternative Toxicological Test Methods
Title | NTP Workshop on Validation and Regulatory Acceptance of Alternative Toxicological Test Methods PDF eBook |
Author | Kenneth Olden |
Publisher | |
Pages | 41 |
Release | 1997-02 |
Genre | |
ISBN | 9780788142338 |
The purpose of the NTP Workshop on Validation & Regulatory Acceptance of Alternative Toxicological Test Methods was to receive comments & recommendations from the public & invited experts on their draft report. It provided recommended criteria & processes for the validation & regulatory acceptance of new & revised toxicological testing methods. This report is a summary of the recommend. developed by the workshop participants. One of the goals of the NTP is developing & validating improved alternative toxicological test methods. The NTP Revit. Act directed NIEHS to: establish criteria for the validation & regulatory acceptance of alternative testing methods: & to recommend a process through which scientifically validated alternative methods can be accepted for regulatory use.
Final Report
Title | Final Report PDF eBook |
Author | |
Publisher | |
Pages | 56 |
Release | 1996 |
Genre | |
ISBN |