Obstructive sleep apnea (OSA) with heavy snoring is a common disorder, affecting more than 1 out of 10 adults, and is closely associated with hypertension, heart disease, stroke, depression, and cognitive decline. Upper airway stimulation therapy is a novel, highly effective alternative method of treatment, involving a surgically implanted device that uses electrical stimulation of muscles to expand the upper airway, thereby addressing the primary cause of OSA. The first of its kind, Upper Airway Stimulation Therapy for Obstructive Sleep Apnea is a comprehensive review of the medical, surgical, and technical aspects of this innovative treatment for OSA. It delves into the current state of knowledge regarding upper airway stimulation, reviewing pathophysiological basis of sleep apnea and the specific mechanism by which upper airway stimulation provides airway support in this disorder. Evidence-based, this book provides practical guidelines for patient selection, clinical outcomes, surgical technique, long-term follow-up and adverse events, as well as for developing an upper airway stimulation program.

The definitive resource on the innovative use of DISE for obstructive sleep apnea Obstructive sleep apnea is the most prevalent sleep-related breathing disorder, impacting an estimated 1.36 billion people worldwide. In the past, OSA was almost exclusively treated with Continuous Positive Airway Pressure (CPAP), however, dynamic assessment of upper airway obstruction with Drug-Induced Sleep Endoscopy (DISE) has been instrumental in developing efficacious alternatives. Drug-Induced Sleep Endoscopy: Diagnostic and Therapeutic Applications by Nico de Vries, Ottavio Piccin, Olivier Vanderveken, and Claudio Vicini is the first textbook on DISE written by world-renowned sleep medicine pioneers. Twenty-four chapters feature contributions from an impressive group of multidisciplinary international experts. Foundational chapters encompass indications, contraindications, informed consent, organization and logistics, patient preparation, and drugs used in DISE. Subsequent chapters focus on treatment outcomes, the role of DISE in therapeutic decision making and upper airway stimulation, pediatric sleep endoscopy, craniofacial syndromes, advanced techniques, and more. Key Highlights Comprehensive video library highlights common and rare DISE findings A full spectrum of sleep disordered breathing and OSA topics, from historic to future perspectives Insightful clinical pearls on preventing errors and managing complications including concentric and epiglottis collapse Discussion of controversial DISE applications including oral appliances and positional and combination therapies This unique book is essential reading for otolaryngology residents, fellows, and surgeons. Clinicians in other specialties involved in sleep medicine will also benefit from this reference, including pulmonologists, neurologists, neurophysiologists, maxillofacial surgeons, and anesthesiologists.

"Obstructive sleep apnea is the most prevalent sleep-related breathing disorder, impacting an estimated 1.36 billion people worldwide. In the past, OSA was almost exclusively treated with Continuous Positive Airway Pressure (CPAP), however, dynamic assessment of upper airway obstruction with Drug-Induced Sleep Endoscopy (DISE) has been instrumental in developing efficacious alternatives. Drug-Induced Sleep Endoscopy: Diagnostic and Therapeutic Applications by Nico de Vries, Ottavio Piccin, Olivier Vanderveken, and Claudio Vicini is the first textbook on DISE written by world-renowned sleep medicine pioneers"--

This book by leading international experts provides an evidence-based approach to electrical stimulation of the upper airway, beginning with patient selection, implant techniques, trouble shootings, patient pathways, titrations during daytime and sleep as also new innovative techniques such as stimulation of the ansa cervicalis and the phrenic nerve. Key Features: · Superbly illustrated schematic drawings and full-colored photographs; · Step-by-step description of surgical concepts and techniques on all of the market available systems (Inspire, Nyxoah, LivaNova, Remede); · Complete online media library with videos on the surgical procedures; · New surgical steps presented for well established procedures (e.g. 2-incicions technique); · Discussion of outcomes, success rates, risks, and potential troubleshooting’s, where evidenced-based data are not available, expert opinion is provided. Upper Airway Stimulation in Obstructive Sleep Apnea will be welcomed by residents, fellows, and board-certified surgeons in otorhinolaryngology and head and neck surgery.

Neuromodulation: Comprehensive Textbook of Principles, Technologies, and Therapies, Second Edition, serves as a comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. Since the publication of the first edition seven years ago, there has been an explosion of knowledge in neuromodulation, optogenetics, bioelectronics medicine and brain computer interfacing. Users will find unique discussions of the fundamental principles of neuromodulation and therapies, and how they are applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs. The book focuses on comprehensive coverage of spinal cord stimulation, non-interventional and interventional brain stimulation, peripheral nerve stimulation, and the emerging fields of neuromodulation, including optogenetics and bioelectronics medicine. Provides a comprehensive reference that covers all aspects of the growing field of neuromodulation Written by international, leading authorities in their respective fields of neuromodulation, pain management, functional neurosurgery and biomedical engineering Includes new chapters on optogenetics, bioelectronics medicine and brain computer interfacing

Finally, a multi-disciplinary approach that covers both the surgical and non-surgical interventions for sleep apnea and snoring. From the editor of Operative Techniques in Otolaryngology, this new reference will quickly become the standard in surgery for this key area within otolaryngology. ., Full-color line drawings illustrate key concepts and create a comprehensive way of learning surgical techniques. Provides consistent, templated chapters and a contemporary, full-color format for quick, easy access to the most up-to-date surgical and non surgical interventions for sleep apnea and snoring. Includes contributions from leaders in neurology, pulmonology, psychiatry, otolaryngology, and oral & maxillofacial surgery. to create a truly multi-disciplinary approach. Covers new and innovative procedures including ZPP (Zeta palatopharyngoplasty), Transpalatal Advancement Pharyngoplasty and Minimally invasive submucosal glossectomy Details when and why surgery is necessary, and how to perform a successful operation for snoring and sleep apnea.