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Oxygen-Ozone therapy is a complementary approach less known than homeopathy and acupuncture because it has come of age only three decades ago. This book clarifies that, in the often nebulous field of natural medicine, the biological bases of ozone therapy are totally in line with classical biochemistry, physiological and pharmacological knowledge. Ozone is an oxidizing molecule, a sort of super active oxygen, which, by reacting with blood components generates a number of chemical messengers responsible for activating crucial biological functions such as oxygen delivery, immune activation, release of hormones and induction of antioxidant enzymes, which is an exceptional property for correcting the chronic oxidative stress present in atherosclerosis, diabetes and cancer. Moreover, by inducing nitric oxide synthase, ozone therapy may mobilize endogenous stem cells, which will promote regeneration of ischemic tissues. The description of these phenomena offers the first comprehensive picture for understanding how ozone works and why. When properly used as a real drug within therapeutic range, ozone therapy does not only does not procure adverse effects but yields a feeling of wellness. Half the book describes the value of ozone treatment in several diseases, particularly cutanious infection and vascular diseases where ozone really behaves as a “wonder drug”. The book has been written for clinical researchers, physicians and ozone therapists, but also for the layman or the patient interested in this therapy.

In 1987, our first book Acupuncture: Textbook and Atlas received rave reviews (e.g., in New England Journal of Medicine). This prompted us to write this smaller, affordable version in order to reach a wider audience. The smaller format has been so successful that we are now into our fourth revised edition. This has given us the opportunity to update and improve the book. For example, nu merous new references to scientific advances have been added. Also the section on traditional Chinese medicine (TCM) was ad ded because it gives a more complete picture of the current prac tice of acupuncture. Acupuncture has come a long way since our first book in 1987. There has been a surge of interest in treating drug addictions by ear acupuncture in 450 centers world wide. The treatment of nau sea and vomiting has been so well tested (scientifically) that the FDA (USA) is considering making this the major indication for acupuncture in America. Research into its efficacy for neurologi cal and pulmonary diseases is also gaining credibility. No longer is chronic pain the only scientifically acceptable use for acupuncture (based on the endorphin mechanism).