Collects Ultimate X-Men #61-65. Emma Frost, Alex Summers and the X-Men's greatest enemy star in an epic new storyline! When teenage mutant Lorna Dane accidentally commits a horrific crime, will the X-Men protect her, or leave her to the fury of S.H.I.E.L.D.?

Humanity now faces mutants, a mysterious sub-species that is gifted with strange and frightening powers. Hidden among the population. they are feared and hated by their human cousins. As rumors and urban myths about their existence spread across the world, the US government creates its own initiative to deal with this threat: the Sentinel Project. Meanwhile two men wage a secret war for the hearts and minds of young mutants everywhere. Charles Xavier has recruited a cadre of students including Cyclops, Jean Grey and Beast, that call themselves the X-Men. But there are others out there, living in fear, struggling to deal with what they are: Ororo Munroe, Bobby Drake and another, more dangerous mutant named Logan. Simultaneously, the terrorist known only as Magneto has assembled The Brotherhood, a militant group dedicated to the overthrow of human authority. A war is on the horizon and these amazing young men and women will decide the future of all humanity! Collects Ultimate X-Men (2000) #1-6.

It is in this insanity that the X-Men emerge. How will these former X-Men fair in a world where they are criminals? Ultimate X-Men (2000) #13-20.

Collects Uncanny X-Men (1981) #201-209; Longshot (1985) #1-6; material from Marvel Fanfare (1982) #33. Chris Claremont and John Romita Jr. are joined by a host of all-star illustrators for a groundbreaking X-Men Masterworks! It’s all in the family for Cyclops as his son Nathan Summers — later known as Cable — is born, and his “Days of Future Past” daughter Rachel comes to terms with her Phoenix Force powers! Storm duels Cyclops for team leadership as the threat of the Beyonder looms, Nightcrawler takes a solo turn in an adventure beautifully drawn by June Brigman, and Barry Windsor-Smith crafts a brutal Wolverine tale. And a showdown between Wolverine and Phoenix presages war with the Hellfire Club and Nimrod! Plus: Ann Nocenti and Arthur Adams’ quintessentially ’80s limited series introducing the dimension-spanning adventurer and future X-Man Longshot is restored for the Masterworks!

Collects Ultimate X-Men #94-97. Regrouping after the devastating battle against Apocalypse, the X-Men encounter a new adversary which seems unstoppable. To fight it, the young mutants must ask themselves: How far are they willing to go and what are they willing to take to raise their game? The answer will test the bonds and shake the team to its very core.

Collects Ultimate X-Men #26-33. Magneto, the X-Men's deadliest villain, returns. They've faced the Weapon X program, Proteus and even the superhuman strikeforce known as The Ultimates. Now, still licking their wounds from their prior battles, can Xavier's mutant team possibly survive the return of their most powerful foe?

A man called Cable comes from the future, his goal: the murder of Charles Xavier. Who is he? The answer will change the X-Men forever.