Trained Immunity-based Vaccines
Title | Trained Immunity-based Vaccines PDF eBook |
Author | Jose Luis Subiza |
Publisher | Frontiers Media SA |
Pages | 195 |
Release | 2021-08-25 |
Genre | Medical |
ISBN | 2889712311 |
Dr. Jose Luis Subiza is the founder and CEO of Inmunotek SL. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Trained Immunity-Based Vaccines
Title | Trained Immunity-Based Vaccines PDF eBook |
Author | José Luis Luis Subiza |
Publisher | |
Pages | 0 |
Release | 2022 |
Genre | Electronic books |
ISBN |
Viral outbreaks have become significant threats to global human public health. New emerging viruses, pathogen mutations, and even the progressive loss of efficacy in some existing vaccines are behind this problem, which is amplified by the rapid virus spread given the ease of current mobility. Taking into account that these outbreaks arise in the absence of conventional effective vaccines, alternative approaches based on trained (innate) immunity are being considered. This immunity is dependent on a functional reprogramming of innate immune cells, leading to an enhanced nonspecific response towards different pathogens, including viruses. Trained immunity-based vaccines (TIbVs), defined as vaccine formulations containing trained immunity inducers, could be used during viral outbreaks to confer non-specific protection but also to enhance adaptive specific immune responses. In this chapter, we aim to illustrate how TIbVs could tackle the above-mentioned situations derived from viral outbreaks, reviewing the potential of available TIbVs in such urgent situations with a special mention to COVID-19.
Innate Immunity in Health and Disease
Title | Innate Immunity in Health and Disease PDF eBook |
Author | Shailendra K. Saxena |
Publisher | BoD – Books on Demand |
Pages | 416 |
Release | 2021-08-25 |
Genre | Medical |
ISBN | 1838807659 |
The book focuses on various aspects and properties of innate immunity, whose deep understanding is integral for safeguarding the human race from further loss of resources and economies due to innate immune response-mediated diseases. Throughout this book, we examine the individual mechanisms by which the innate immune response acts to protect the host from pathogenic infectious agents and other non-communicable diseases. Written by experts in the field, the volume discusses the significance of macrophages in infectious disease, tumor metabolism, and muscular disorders. Chapters cover such topics as the fate of differentiated macrophages and the molecular pathways that are important for the pathologic role of macrophages.
Immunopotentiators in Modern Vaccines
Title | Immunopotentiators in Modern Vaccines PDF eBook |
Author | Virgil Schijns |
Publisher | Elsevier |
Pages | 396 |
Release | 2005-12-19 |
Genre | Medical |
ISBN | 0080457215 |
Immunopotentiators in Modern Vaccines provides an in-depth insight and overview of a number of most promising immunopotentiators in modern vaccines. In contrast to existing books on the subject it provides recent data on the critical mechanisms governing the activity of vaccine adjuvants and delivery systems. Knowledge of immunological pathways and scenarios of the cells and molecules involved is described and depicted in comprehensive illustrations. Contributions from leading international authorities in the field Well-illustrated, informative figures present the interactions between immunopotentiators and the host immune system Each chapter lists advantages and potential hurdles for achieving a practical application for the specific immunopentiator
Heterologous Immunity: Implications and Applications in Vaccines and Immunotherapies
Title | Heterologous Immunity: Implications and Applications in Vaccines and Immunotherapies PDF eBook |
Author | Babita Agrawal |
Publisher | Frontiers Media SA |
Pages | 168 |
Release | 2020-08-27 |
Genre | |
ISBN | 2889639657 |
Vaccines and approaches that target trained immunity in COVID-19: Immunological mechanisms of action and delivery
Title | Vaccines and approaches that target trained immunity in COVID-19: Immunological mechanisms of action and delivery PDF eBook |
Author | Yongjun Sui |
Publisher | Frontiers Media SA |
Pages | 181 |
Release | 2023-06-30 |
Genre | Medical |
ISBN | 2832527736 |
The Vaccine Book
Title | The Vaccine Book PDF eBook |
Author | Barry R. Bloom |
Publisher | Academic Press |
Pages | 666 |
Release | 2016-06-23 |
Genre | Medical |
ISBN | 012805400X |
The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child’s risk. Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines Gives new ideas about future vaccines and concepts Introduces new vaccines and concepts Gives ideas about challenges facing public and private industrial investors in the vaccine area Discusses the problem of declining immunization rates and vaccine hesitancy