During the last years, the role of titanium and zirconium in organic synthesis has dramatically increased and nowadays, no synthetic chemist can afford to be without a sound knowledge of this fascinating organometal chemistry. This unique book, edited by Ilan Marek, thus summarizes the numerous applications and developments of these two group 4 early transition metal complexes. A plethora of internationally renowned experts and leading scientists in this field cover all the significant aspects of this increasingly important part of organic chemistry and bring the reader up to date. A particularly attractive and useful feature is the inclusion of typical experimental procedures, chosen for broad utility and application. This comprehensive demonstrates the diversity and the applications of these important compounds and is a must-have for all chemists working in organometallic or synthetic organic chemistry.

Organometallic Chemistry of Titanium, Zirconium, and Hafnium covers the chemistry of organic complexes of titanium, zirconium, and hafnium having metal-to-carbon linkage. This book is organized into eight chapters that consider the significant developments in delineating the chemistry of these metal derivatives. This book starts with a description of the stability and bonding in cyclopentadienyl derivatives of the metals, based on the thermodynamic and spectroscopic evidence. The remaining chapters discuss the preparation and reactions of titanium-, zirconium-, and hafnium-bonded organic compounds. These chapters also look into the synthetic difficulties encountered from the reactions and preparation of these compounds. The stabilization and adduct formation of these metal complexes are also explored. Organic chemists and organic chemistry researchers and students will find this book invaluable.

Organometallic Chemistry of Titanium, Zirconium, and Hafnium...

Titanium has been used to perform many kinds of reactions in organic and inorganic chemistry. The present book is concerned primarily with a new development in titanium chemistry which is useful in organic synthesis. In 1979/80 it was discovered that the titanation of classical carbanions using C1TiX leads to species with reduced basicity and reactivity. This increases 3 chemo-, regio-and stereo selectivity in reactions with organic compounds such as aldehydes, ketones and alkyl halides. Many new examples have been reported in recent times. Since the nature of the ligand X at titanium can be widely varied, the electronic and steric nature of the reagents is easily controlled. This helps in predicting the stereochemical outcome of many of the C-C bond forming reactions, but the trial and error method is still necessary in other cases. One of the ultimate objectives of chemistry is to understand correlations between structure and reactivity. Although this goal has not been reached in the area of organotitanium chemistry, appreciable progress has been made. A great deal of physical and computational data of organotitanium compounds described in the current and older literature (e. g. , Ziegler-Natta type catalysts) has been reported by polymer, inorganic and theoretical chemists. It is summarized in Chapter 2 of this book, because some aspects are useful in understanding reactivity and selectivity of organo titanium compounds in organic synthesis as described in the chapters which follow.

The Chemistry of Titanium, Zirconium and Hafnium deals with the chemistry of titanium, zirconium, and hafnium and covers topics ranging from the occurrence and metallurgy of all three elements to their nuclear, physical, and chemical properties as well as analytical chemistry. The compounds of titanium, zirconium, and hafnium are also discussed. This volume is comprised of two chapters and opens with a historical overview and discovery of titanium, along with its occurrence and distribution, metallurgical aspects, and nuclear and physicochemical properties. The compounds of titanium are also considered, including alloys and complexes; hydrides and oxides; halides and oxyhalides; titanates and antimonides; and carbides and borides. The second chapter is devoted to zirconium and hafnium, their occurrence and metallurgy; and physical, chemical, and biological properties. Compounds of zirconium and hafnium are described, from alloys and hydrides to zirconates and hafnates; nitrides, phosphides, and arsenides; carbides, silicides, and germanides; molybdates, tungstates, halates, and perchlorates; alkoxides, mercaptides, and dithiocarbamates; and amides, alkylamides, triazenes, phthalocyanines, and bipyridyls. This book will be a valuable source of information for inorganic chemists.

The second edition of Comprehensive Organic Synthesis—winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers—builds upon the highly respected first edition in drawing together the new common themes that underlie the many disparate areas of organic chemistry. These themes support effective and efficient synthetic strategies, thus providing a comprehensive overview of this important discipline. Fully revised and updated, this new set forms an essential reference work for all those seeking information on the solution of synthetic problems, whether they are experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis, Second Edition, Nine Volume Set an invaluable source, providing an authoritative overview of core concepts. Winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers Contains more than170 articles across nine volumes, including detailed analysis of core topics such as bonds, oxidation, and reduction Includes more than10,000 schemes and images Fully revised and updated; important growth areas—including combinatorial chemistry, new technological, industrial, and green chemistry developments—are covered extensively