"Splendid" —New York Times "Mind-bending." —Wall Street Journal "Brilliantly original. The best new novel I've read this year." —Salman Rushdie A daring, kaleidoscopic novel about the clash of empires and ideas, told through a tennis match in the sixteenth century between the radical Italian artist Caravaggio and the Spanish poet Francisco de Quevedo, played with a ball made from the hair of the beheaded Anne Boleyn. The poet and the artist battle it out in Rome before a crowd that includes Galileo, a Mary Magdalene, and a generation of popes who would throw the world into flames. In England, Thomas Cromwell and Henry VIII execute Anne Boleyn, and her crafty executioner transforms her legendary locks into those most-sought-after tennis balls. Across the ocean in Mexico, the last Aztec emperors play their own games, as the conquistador Hernán Cortés and his Mayan translator and lover, La Malinche, scheme and conquer, fight and f**k, not knowing that their domestic comedy will change the course of history. In a remote Mexican colony a bishop reads Thomas More’s Utopia and thinks that it’s a manual instead of a parody. And in today’s New York City, a man searches for answers to impossible questions, for a book that is both an archive and an oracle. Álvaro Enrigue’s mind-bending story features assassinations and executions, hallucinogenic mushrooms, bawdy criminals, carnal liaisons and papal schemes, artistic and religious revolutions, love and war. A blazingly original voice and a postmodern visionary, Enrigue tells the grand adventure of the dawn of the modern era, breaking down traditions and upending expectations, in this bold, powerful gut-punch of a novel. Game, set, match. “Sudden Death is the best kind of puzzle, its elements so esoteric and wildly funny that readers will race through the book, wondering how Álvaro Enrigue will be able to pull a novel out of such an astonishing ball of string. But Enrigue absolutely does; and with brilliance and clarity and emotional warmth all the more powerful for its surreptitiousness.” —Lauren Groff, New York Times-bestselling author of Fates and Furies "Engrossing... rich with Latin and European history." —The New Yorker "[A] bawdy, often profane, sprawling, ambitious book that is as engaging as it is challenging.” —Vogue

Fast, furious and fatal . . . a pair of killers seek brutal revenge. When a homeless veteran is found dead in a squalid Sacramento alley, FBI special agent Megan Elliott vows to find the murdered hero’s killer. Her investigation gets complicated fast, for the victim, a former Delta Force soldier, is just one link in a nationwide spree of torture and murder. Straight off a job rescuing medical missionaries, soldier-for-hire Jack Kincaid returns to his home base in the Texas border town of Hidalgo only to receive the news that one of his closest colleagues–also ex-military–has been brutally murdered. Faced with an inept local police force, Jack takes matters into his own hands. Now, as part of a national task force to stop the sadistic killings, by-the-book Megan and burn-the-book Jack form a tense alliance, sparked with conflict and temptation. But they struggle against more than passion, for a vicious pair of killers has only just begun a rampage of evil . . . and the primary target is much closer than Megan suspects.

This book dedicates the first seven chapters to cardiac electrophysiological dysfunction that can lead to ventricular fibrillation and sudden death. The next six chapters expand the topics of sudden death to other causes. Brugada Syndrome is the top cause of non-traumatic sudden death in young males of Southeastern Asian and southern European origins. Chapters One and Two review extensively the history and current status, mechanisms of arrhythmias, and related gene mutations in Brugada Syndrome, and discuss gaps in the current knowledge. Chapter Three presents clinical studies on the A1180V and R1193Q mutations of the cardiac sodium channel gene, SCN5A. The authors identified R1193Q mutation in 12.8%-16% of a healthy Chinese population. This result prompted the question of whether SCN5A mutations are still the top genetic bases of Brugada and long QT syndromes. Chapters Four, Five and Seven discuss the pathophysiology causes, risk factors, predictors, prevention, and possible therapeutical strategies of sudden cardiac death. Chapter Six reviews the scope and causes of sudden cardiac death in athletics.Chapter Seven is dedicated to the roles of electrical cardiac systole in sudden death. Chapter Eight reviews sudden death related to cardiac and brain tumours, pulmonary tumour embolism, asphyxia, massive exsanguinations, and their pathophysiology. Chapter Nine summarises the pathophysiology of sudden death caused by myocardial tuberculosis. Chapter Ten introduces pathophysiology of sudden death during hot baths in deep bathtubs, which occurs frequently in elderly people in Japan. Chapter Eleven discusses air pollution as a trigger of sudden death. Chapter Twelve presents biochemical, cytological and histopathological examination of sudden unexpected death in infancy. The last chapter of the book, Chapter Thirteen, reviews post-mortem cardiac markers in different body fluids and their application in forensic pathology diagnosis of sudden cardiac death. In combination, these chapters cover a broad range of topics about sudden death.

This volume covers aspects of sudden infant and early childhood death, ranging from issues with parental grief, to the most recent theories of brainstem neurotransmitters. It also deals with the changes that have occurred over time with the definitions of SIDS (sudden infant death syndrome), SUDI (sudden unexpected death in infancy) and SUDIC (sudden unexpected death in childhood). The text will be indispensable for SIDS researchers, SIDS organisations, paediatric pathologists, forensic pathologists, paediatricians and families, in addition to residents in training programs that involve paediatrics. It will also be of use to other physicians, lawyers and law enforcement officials who deal with these cases, and should be a useful addition to all medical examiner/forensic, paediatric and pathology departments, hospital and university libraries on a global scale. Given the marked changes that have occurred in the epidemiology and understanding of SIDS and sudden death in the very young over the past decade, a text such as this is very timely and is also urgently needed.