From the National Book Award finalist and author of "When Smoke Ran Like Water" comes this searing, haunting, and deeply personal account of how a major public health effort was diverted and distorted for private gain.

After reviewing the history of cancer and its impact on the population, Dr. Faguet exposes the antiquated notions that have driven cancer drug development, documents the stagnation in treatment outcomes despite major advances in cancer genomics and growing NCI budgets, and identifies the multiple factors that sustain the status quo. He shows that, contrary to frequent announcements of breakthroughs, our current cancer control model cannot eradicate most cancers and the reasons why. Significantly, this book also delineates a way forward via a shift from the discredited cell-kill approach of the past to an integrated, evidence-driven cancer control paradigm based on prevention, early diagnosis, and pharmacogenomics. The author's views are based on data published in mainstream scientific journals and other reliable references, 432 of which are cited.

An unprecedented constellation of experts—leading cancer doctors, policymakers, cutting-edge researchers, national advocates, and more—explore the legacy and the shortcomings from the fifty-year war on cancer and look ahead to the future. The longest war in the modern era, longer than the Cold War, has been the war on cancer. Cancer is a complex, evasive enemy, and there was no quick victory in the fight against it. But the battle has been a monumental test of medical and scientific research and fundraising acumen, as well as a moral and ethical challenge to the entire system of medicine. In A New Deal for Cancer, some of today’s leading thinkers, activists, and medical visionaries describe the many successes in the long war and the ways in which our deeper failings as a society have held us back from a more complete success. Together they present an unrivaled and nearly complete map of the battlefield across dimensions of science, government, equity, business, the patient provider experience, and more, documenting our emerging understanding of cancer’s many unique dimensions and offering bold new plans to enable the American health care system to deliver progress and hope to all patients.

A decade ago Leaf, a cancer survivor himself, began to investigate why we had made such limited progress fighting this terrifying disease. The result is a gripping narrative that reveals why the public's immense investment in research has been badly misspent, why scientists seldom collaborate and share their data, why new drugs are so expensive yet routinely fail, and why our best hope for progress-- brilliant young scientists-- are now abandoning the search for a cure.

Collaboration in the Holocaust. Murderous and torturous medical experiments. The "euthanasia" of hundreds of thousands of people with mental or physical disabilities. Widespread sterilization of "the unfit." Nazi doctors committed these and countless other atrocities as part of Hitler's warped quest to create a German master race. Robert Proctor recently made the explosive discovery, however, that Nazi Germany was also decades ahead of other countries in promoting health reforms that we today regard as progressive and socially responsible. Most startling, Nazi scientists were the first to definitively link lung cancer and cigarette smoking. Proctor explores the controversial and troubling questions that such findings raise: Were the Nazis more complex morally than we thought? Can good science come from an evil regime? What might this reveal about health activism in our own society? Proctor argues that we must view Hitler's Germany more subtly than we have in the past. But he also concludes that the Nazis' forward-looking health activism ultimately came from the same twisted root as their medical crimes: the ideal of a sanitary racial utopia reserved exclusively for pure and healthy Germans. Author of an earlier groundbreaking work on Nazi medical horrors, Proctor began this book after discovering documents showing that the Nazis conducted the most aggressive antismoking campaign in modern history. Further research revealed that Hitler's government passed a wide range of public health measures, including restrictions on asbestos, radiation, pesticides, and food dyes. Nazi health officials introduced strict occupational health and safety standards, and promoted such foods as whole-grain bread and soybeans. These policies went hand in hand with health propaganda that, for example, idealized the Führer's body and his nonsmoking, vegetarian lifestyle. Proctor shows that cancer also became an important social metaphor, as the Nazis portrayed Jews and other "enemies of the Volk" as tumors that must be eliminated from the German body politic. This is a disturbing and profoundly important book. It is only by appreciating the connections between the "normal" and the "monstrous" aspects of Nazi science and policy, Proctor reveals, that we can fully understand not just the horror of fascism, but also its deep and seductive appeal even to otherwise right-thinking Germans.

Cancer touches everybody’s life in one way or another. But most of us know very little about how the disease works, why we treat it the way we do, and the personalities whose dedication got us where we are today. For fifty years, Dr. Vincent T. DeVita Jr. has been one of those key players: he has held just about every major position in the field, and he developed the first successful chemotherapy treatment for Hodgkin’s lymphoma, a breakthrough the American Society of Clinical Oncologists has called the top research advance in half a century of chemotherapy. As one of oncology’s leading figures, DeVita knows what cancer looks like from the lab bench and the bedside. The Death of Cancer is his illuminating and deeply personal look at the science and the history of one of the world’s most formidable diseases. In DeVita’s hands, even the most complex medical concepts are comprehensible. Cowritten with DeVita’s daughter, the science writer Elizabeth DeVita-Raeburn, The Death of Cancer is also a personal tale about the false starts and major breakthroughs, the strong-willed oncologists who clashed with conservative administrators (and one another), and the courageous patients whose willingness to test cutting-edge research helped those oncologists find potential treatments. An emotionally compelling and informative read, The Death of Cancer is also a call to arms. DeVita believes that we’re well on our way to curing cancer but that there are things we need to change in order to get there. Mortality rates are declining, but America’s cancer patients are still being shortchanged—by timid doctors, by misguided national agendas, by compromised bureaucracies, and by a lack of access to information about the strengths and weaknesses of the nation’s cancer centers. With historical depth and authenticity, DeVita reveals the true story of the fight against cancer. The Death of Cancer is an ambitious, vital book about a life-and-death subject that touches us all.

Written by a highly regarded historian of science, this meticulouly researched, eminently fair, and very provocative book attempts to answer the question: Why, given all the time and money spent on cancer research, can't we get consistent answers to the most fundamental questions about prevention and treatment?