This volume deals with the transosseous external fixation techniques that I have been developing over the course of the past 40 years. During this time, our research in medicine, biology and engineering has led to the evolution of more than 800 unique, highly effective methods of treatment that extend beyond the realm of traumatology and orthopedics. The book features a comprehensive theoretical and clinical description of the biologic laws governing the depen dence of the shape-forming processes of bones and joints upon the adequacy of blood supply, as well as a delineation of the effect of tension-stress upon the genesis and growth of tissues. I have in cluded our latest data on tissue growth and regeneration during transosseous osteosyntheses. The book summarizes the biomechanical principles of applica tion of my apparatus; clinical cases selected from more than 25000 patients illustrate the management of some of the most complex disorders of the locomotor system. New solutions to many therapeutic problems are described. In particular, severe limb trauma with large defects of bone, vessels, nerves and skin can be managed without resort to transplantation. Radical debridement surgery can be followed by a one-step restora tion of the missing tissue, thus decreasing the likelihood of a serious wound infection or an amputation.

This volume deals with the transosseous external fixation techniques that I have been developing over the course of the past 40 years. During this time, our research in medicine, biology and engineering has led to the evolution of more than 800 unique, highly effective methods of treatment that extend beyond the realm of traumatology and orthopedics. The book features a comprehensive theoretical and clinical description of the biologic laws governing the depen dence of the shape-forming processes of bones and joints upon the adequacy of blood supply, as well as a delineation of the effect of tension-stress upon the genesis and growth of tissues. I have in cluded our latest data on tissue growth and regeneration during transosseous osteosyntheses. The book summarizes the biomechanical principles of applica tion of my apparatus; clinical cases selected from more than 25000 patients illustrate the management of some of the most complex disorders of the locomotor system. New solutions to many therapeutic problems are described. In particular, severe limb trauma with large defects of bone, vessels, nerves and skin can be managed without resort to transplantation. Radical debridement surgery can be followed by a one-step restora tion of the missing tissue, thus decreasing the likelihood of a serious wound infection or an amputation.

The Ilizarov device has revolutionized the treatment of non-healing fractures and the correction of deformities. This book supplies all the information required in order to use the Ilizarov and other external fixation devices optimally; it will serve as an indispensable manual for both trainee and experienced orthopedic surgeons. Biomechanical principles, preoperative preparation, and the use of a system of coordinates to allow safer insertion of K-wires and half pins are thoroughly discussed. External fixation of a variety of fractures in different pathologic settings is then clearly explained in a series of detailed chapters with the aid of high-quality illustrations. Numerous case reports are included to illustrate the results of different treatment methods. In addition, postoperative management and treatment of complications are described. Since the first edition the text has been thoroughly updated, with inclusion of contributions from leading world experts.

Biomaterials for Surgical Operation offers a review of the latest advances made in developing bioabsorbable devices for surgical operations which include surgical adhesives (sealants), barriers for the prevention of tissue adhesion, polymers for fractured bone fixation, growth factors for the promotion of wound healing, and sutures. Over the years, many descriptions of biomaterials have appeared in academic journals and books, but most of them have been devoted to limited clinical areas. This is in marked contrast with this volume which covers a wide range of bioabsorbable devices used in surgery from a practical point of view. The currently applied polymeric devices are critical in surgery, but all involve serious problems due to their poor performance. For instance, fibrin glue, the most widely used surgical sealant, can produce only a weak gel with low adhesive strength to tissues, accentuating the limited effectiveness of current treatment options. Likewise, the currently available barrier membranes cannot fully prevent tissue adhesion at the acceptable level and are, moreover, not easy to handle with endoscopes due to their poor mechanical properties. Biomaterials for Surgical Operation is aimed at those who are interested in expanding their knowledge of how the problems associated with the currently used devices for surgical operation can be solved. It primarily focuses on the absorbable biomaterials which are the main components of these medical devices.

Providing a comprehensive overview of the current orthopedic uses of intramedullary devices, this practical, well-illustrated guide opens with a review of the history of limb lengthening from the early external fixator up to Ilizarov’s monumental discoveries, with a summary of the biology of new bone formation in a widening distraction gap. This is followed by post-Ilizarov developments with external fixators designed to ease application and increase patient tolerance of such devices, as well as a discussion of the intramedullary lengthening devices from the earliest mechanical distractors to the most modern implants, detailing the surgical principles, pre-operative planning and specific operative techniques for each. Concluding chapters focus on preventing and dealing with complications from the surgery and day-to-day post-operative management. A unique feature of the book is a cross-section atlas of the upper and lower limbs that will assist surgeons to avoid impaling neurovascular structures during the minimally invasive portions of operative insertion of the implants. Intramedullary Limb Lengthening: Principles and Practice is an ideal, on-the-spot resource for orthopedic surgeons, residents and trainees treating pediatric and adult limb deformities and length deficiencies, as well as physical therapists and other health care providers who manage such patients post-operatively.

Bone and Cartilage Engineering provides a complete overview of recent knowledge in bone and cartilage tissue engineering. It follows a logical approach to the various aspects of extracorporal bone and cartilage tissue engineering. The cooperation between a basic scientist and a clinician made it possible to structure the book's content and style according to the interdisciplinary character of the field. The comprehensive nature of the book, including detailed descriptions of laboratory procedures, preclinical approaches, clinical applications, and regulatory issues, will make it an invaluable basis for everyone working in this field. This book will serve as a fundamental tool for basic researchers to establish or refine tissue engineering techniques as well as for clinicians to understand and use this modern therapeutic option.