In this New York Times bestseller and longlist nominee for the National Book Award, “our greatest living chronicler of the natural world” (The New York Times), David Quammen explains how recent discoveries in molecular biology affect our understanding of evolution and life’s history. In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important; we now know that roughly eight percent of the human genome arrived sideways by viral infection—a type of HGT. In The Tangled Tree, “the grandest tale in biology….David Quammen presents the science—and the scientists involved—with patience, candor, and flair” (Nature). We learn about the major players, such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health. “David Quammen proves to be an immensely well-informed guide to a complex story” (The Wall Street Journal). In The Tangled Tree, he explains how molecular studies of evolution have brought startling recognitions about the tangled tree of life—including where we humans fit upon it. Thanks to new technologies, we now have the ability to alter even our genetic composition—through sideways insertions, as nature has long been doing. “The Tangled Tree is a source of wonder….Quammen has written a deep and daring intellectual adventure” (The Boston Globe).

In this New York Times bestseller and longlist nominee for the National Book Award, “our greatest living chronicler of the natural world” (The New York Times), David Quammen explains how recent discoveries in molecular biology affect our understanding of evolution and life’s history. In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important; we now know that roughly eight percent of the human genome arrived sideways by viral infection—a type of HGT. In The Tangled Tree, “the grandest tale in biology….David Quammen presents the science—and the scientists involved—with patience, candor, and flair” (Nature). We learn about the major players, such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health. “David Quammen proves to be an immensely well-informed guide to a complex story” (The Wall Street Journal). In The Tangled Tree, he explains how molecular studies of evolution have brought startling recognitions about the tangled tree of life—including where we humans fit upon it. Thanks to new technologies, we now have the ability to alter even our genetic composition—through sideways insertions, as nature has long been doing. “The Tangled Tree is a source of wonder….Quammen has written a deep and daring intellectual adventure” (The Boston Globe).

Longlisted for the National Book Award for Nonfiction and A New York Times Notable Book of 2018. Our understanding of the ‘tree of life’, with powerful implications for human genetics, human health and our own human nature, has recently completely changed.

In recent years, the use of molecular data to build phylogenetic trees and sophisticated computer-aided techniques to analyze them have led to a revolution in the study of cospeciation. Tangled Trees provides an up-to-date review and synthesis of current knowledge about phylogeny, cospeciation, and coevolution. The opening chapters present various methodological and theoretical approaches, ranging from the well-known parsimony approach to "jungles" and Bayesian statistical models. Then a series of empirical chapters discusses detailed studies of cospeciation involving vertebrate hosts and their parasites, including nematodes, viruses, and lice. Tangled Trees will be welcomed by researchers in a wide variety of fields, from parasitology and ecology to systematics and evolutionary biology. Contributors: Sarah Al-Tamimi, Michael A. Charleston, Dale H. Clayton, James W. Demastes, Russell D. Gray, Mark S. Hafner, John P. Huelsenbeck, J.-P. Hugot, Kevin P. Johnson, Peter Kabat, Bret Larget, Joanne Martin, Yannis Michalakis, Roderic D. M. Page, Ricardo L. Palma, Adrian M. Paterson, Susan L. Perkins, Andy Purvis, Bruce Rannala, David L. Reed, Fredrik Ronquist, Theresa A. Spradling, Jason Taylor, Michael Tristem

"Quammen brilliantly and powerfully re-creates the 19th century naturalist's intellectual and spiritual journey."--Los Angeles Times Book Review Twenty-one years passed between Charles Darwin's epiphany that "natural selection" formed the basis of evolution and the scientist's publication of On the Origin of Species. Why did Darwin delay, and what happened during the course of those two decades? The human drama and scientific basis of these years constitute a fascinating, tangled tale that elucidates the character of a cautious naturalist who initiated an intellectual revolution.

Used widely in non-majors biology classes, The Tangled Bank is the first textbook about evolution intended for the general reader. Zimmer, an award-winning science writer, takes readers on a fascinating journey into the latest discoveries about evolution. In the Canadian Arctic, paleontologists unearth fossils documenting the move of our ancestors from sea to land. In the outback of Australia, a zoologist tracks some of the world’s deadliest snakes to decipher the 100-million-year evolution of venom molecules. In Africa, geneticists are gathering DNA to probe the origin of our species. In clear, non-technical language, Zimmer explains the central concepts essential for understanding new advances in evolution, including natural selection, genetic drift, and sexual selection. He demonstrates how vital evolution is to all branches of modern biology—from the fight against deadly antibiotic-resistant bacteria to the analysis of the human genome.

Literary Nonfiction. Jewish Studies. A TANGLED TREE: MY FATHER'S PATH TO IMMORTALITY begins in the summertime, as Aiyanna follows her father Moshe on their big adventures--living on a nude beach on Kauai, chasing the Grateful Dead in an old milk truck, offering prayers to the Wailing Wall, lighting candles in the Shabbas House in Massachusetts, which is always their base. Twelve years later and after years of distance, Moshe arrives at her door, barefoot, with a beard to his chest, a sage of Judah adorned in fine Indian silk. They have reunited with a shared vision: To record his life story and memoir. Born as a Polish Jew on the run from the Nazi invasion launching World War II, Moshe and his family barely escape the oncoming Holocaust. They find refuge on a kolhoz in Russia, return to Poland to encounter their deepest grief, move to a settlement in Israel, and eventually immigrate to Toronto. Despite his poverty and against the odds, Moshe becomes an academic, a Harvard professor, psychologist and rabbi. But by the age of 30, something inside him shifts, and he reaches for more. During the psychedelic intrigue of the '70s, he turns to a healer named Salvador, a man who gives him his first taste of LSD in a cathartic ritual. He travels to India, where a mystic named Osho introduces him to the love that heals. Across the world he seeks healing, traveling on an ever-morphing spiritual journey. Moshe fathers six children with five women. Aiyanna is his fourth, born out of wedlock to an astrologer with many names. Moshe's epic personality, wisdom, stories, and memories suddenly collide into Aiyanna's life, filling her one- bedroom apartment, where they record together for a month, fighting, laughing, cooking dinners, ultimately rebuilding their lost relationship. When Moshe leaves, Aiyanna is left with a lifetime of pages to be written. But the book she writes is far from the reflection Moshe expected. Aiyanna's life experiences stand beside his; she writes of her siblings, their mothers, and the tangled nest of contention, love and disconnection between them all. From this portrayal, Moshe feels both betrayed and deeply wounded, confirmed that all women are only destined to hurt him. A TANGLED TREE is more than a memoir. It tells two conflicting but inseparable truths, painting a dynamic portrait of a man, of his parents' miraculous escape, of the six children he fathered, and of a daughter determined to tell their story, and carry it forward until the end.