This biographical study illuminates the important yet misunderstood figure of Barbara McClintock, the Nobel Prize winning geneticist. Comfort replaces the myth with a new story, rich with new understandings of women in science.

In this New York Times bestseller and longlist nominee for the National Book Award, “our greatest living chronicler of the natural world” (The New York Times), David Quammen explains how recent discoveries in molecular biology affect our understanding of evolution and life’s history. In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important; we now know that roughly eight percent of the human genome arrived sideways by viral infection—a type of HGT. In The Tangled Tree, “the grandest tale in biology….David Quammen presents the science—and the scientists involved—with patience, candor, and flair” (Nature). We learn about the major players, such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health. “David Quammen proves to be an immensely well-informed guide to a complex story” (The Wall Street Journal). In The Tangled Tree, he explains how molecular studies of evolution have brought startling recognitions about the tangled tree of life—including where we humans fit upon it. Thanks to new technologies, we now have the ability to alter even our genetic composition—through sideways insertions, as nature has long been doing. “The Tangled Tree is a source of wonder….Quammen has written a deep and daring intellectual adventure” (The Boston Globe).

Modern web applications are built on a tangle of technologies that have been developed over time and then haphazardly pieced together. Every piece of the web application stack, from HTTP requests to browser-side scripts, comes with important yet subtle security consequences. To keep users safe, it is essential for developers to confidently navigate this landscape. In The Tangled Web, Michal Zalewski, one of the world’s top browser security experts, offers a compelling narrative that explains exactly how browsers work and why they’re fundamentally insecure. Rather than dispense simplistic advice on vulnerabilities, Zalewski examines the entire browser security model, revealing weak points and providing crucial information for shoring up web application security. You’ll learn how to: –Perform common but surprisingly complex tasks such as URL parsing and HTML sanitization –Use modern security features like Strict Transport Security, Content Security Policy, and Cross-Origin Resource Sharing –Leverage many variants of the same-origin policy to safely compartmentalize complex web applications and protect user credentials in case of XSS bugs –Build mashups and embed gadgets without getting stung by the tricky frame navigation policy –Embed or host user-supplied content without running into the trap of content sniffing For quick reference, "Security Engineering Cheat Sheets" at the end of each chapter offer ready solutions to problems you’re most likely to encounter. With coverage extending as far as planned HTML5 features, The Tangled Web will help you create secure web applications that stand the test of time.

Used widely in non-majors biology classes, The Tangled Bank is the first textbook about evolution intended for the general reader. Zimmer, an award-winning science writer, takes readers on a fascinating journey into the latest discoveries about evolution. In the Canadian Arctic, paleontologists unearth fossils documenting the move of our ancestors from sea to land. In the outback of Australia, a zoologist tracks some of the world’s deadliest snakes to decipher the 100-million-year evolution of venom molecules. In Africa, geneticists are gathering DNA to probe the origin of our species. In clear, non-technical language, Zimmer explains the central concepts essential for understanding new advances in evolution, including natural selection, genetic drift, and sexual selection. He demonstrates how vital evolution is to all branches of modern biology—from the fight against deadly antibiotic-resistant bacteria to the analysis of the human genome.

A vital updating of a seminal work of science First published to great acclaim twenty years ago, T"he Tangled Wing" has become required reading for anyone interested in the biological roots of human behavior. Since then, revolutions have taken place in genetics, molecular biology, and neuroscience. All of these innovations have been brought into account in this greatly expanded edition of a book originally called an "overwhelming achievement" by "The Times Literary Supplement," A masterful synthesis of biology, psychology, anthropology, and philosophy, "The Tangled Wing" reveals human identity and activity to be an intricately woven fabric of innumerable factors. Melvin Konner's sensitive and straightforward discussion ranges across topics such as the roots of aggression, the basis of attachment and desire, the differences between the sexes, and the foundations of mental illness.

In this loose retelling of "Wuthering Heights" set in Missouri during the Civil War, when free-spirited seventeen-year-old Catrina discovers a mysterious young man with amnesia on her family's sorghum farm, they fall passionately in love, scandalizing intolerant family members and neighbors.

Almost daily we hear news stories, advertisements, and scientific reports that promise genetic medicine will make us live longer, enable doctors to identify and treat diseases before they start, and individualize our medical care. But surprisingly, a century ago eugenicists were making the same promises. The Science of Human Perfection traces the history of the promises of medical genetics and of the medical dimension of eugenics. The book also considers social and ethical issues that cast troublesome shadows over these fields./divDIV DIVKeeping his focus on America, science historian Nathaniel Comfort introduces the community of scientists, physicians, and public health workers who have contributed to the development of medical genetics from the nineteenth century to today. He argues that medical genetics is closely related to eugenics, and indeed the two cannot be fully understood separately. He also carefully examines how the desire to relieve suffering and to improve ourselves genetically, though noble, may be subverted. History makes clear that as patients and consumers we must take ownership of genetic medicine, using it intelligently, knowledgeably, and skeptically, lest pernicious interests trump our own./div