The Membrane Hypothesis of Aging offers the most comprehensive, multidisciplinary description of the cell maturation and aging process. The membrane hypothesis of aging (MHA) described in this book is based on the actual multidisciplinary knowledge of cell morphology, physiology, and biochemistry. The solid basis of known facts explains the destructive, progressive, intrinsic, and universal character of the aging process. The book interprets other aging theories, including free radical theory of aging, dysdifferentiation hypothesis of aging and cancer, and the accumulation theories. It presents important issues for future research. The book also outlines the possibilities of an efficient, preventive, anti-aging drug design, and presents the first promising results of such research activity.

This book introduces the “strike of default” (SOD) benchmark concept. The author determines the SOD through cross-sectional pricing between the credit market and the option market, considering the same underlying. The idea of the SOD is to combine the implied probability of default from both markets to get a time-depending share price, at which the markets believe the underlying will default. By means of credit default swaps (CDS) and option pricing methods, the SOD is determined for any exchange-listed company, where option and CDS market data are available.

DigiCat Publishing presents to you this special edition of "The Foundations of Science: Science and Hypothesis, The Value of Science, Science and Method" by Henri Poincaré. DigiCat Publishing considers every written word to be a legacy of humankind. Every DigiCat book has been carefully reproduced for republishing in a new modern format. The books are available in print, as well as ebooks. DigiCat hopes you will treat this work with the acknowledgment and passion it deserves as a classic of world literature.

An approach to the modeling of and the reasoning under uncertainty. The book develops the Dempster-Shafer Theory with regard to the reliability of reasoning with uncertain arguments. Of particular interest here is the development of a new synthesis and the integration of logic and probability theory. The reader benefits from a new approach to uncertainty modeling which extends classical probability theory.

Fundamental Principles of Oxidative Stress in Metabolism and Reproduction: Prevention and Management is a comprehensive resource for anyone needing awareness and recognition of oxidative stress as a basic component of disease to determine the precise treatment plan considering the cause of the disease. It describes the effects of oxidative stress in the human body, the detection of metabolic changes, psychological impact and effect on reproductive outcomes. In addition, it discusses alterations at the cellular level occurring due to oxidative stress along with the genetic aspects involved in its pathogenesis. - Provides a holistic approach to the impact of oxidative stress on various systems - Incorporates recent advances in basic sciences for improvement in oxidative stress leading to better prognosis of metabolic conditions - Summarizes knowledge to detect oxidative stress for improvement of fertility outcomes

The architecture of the human language faculty has been one of the main foci of the linguistic research of the last half century. This branch of linguistics, broadly known as Generative Grammar, is concerned with the formulation of explanatory formal accounts of linguistic phenomena with the ulterior goal of gaining insight into the properties of the 'language organ'. The series comprises high quality monographs and collected volumes that address such issues. The topics in this series range from phonology to semantics, from syntax to information structure, from mathematical linguistics to studies of the lexicon.

Free radicals have been implicated in a entire host of different human disease states, which suggests that although they may not have a pivotal causal role, they are involved in the perpetuation of disease. In recentyears, it has become evident that although free radicals most certainly do have this role in perpetuating inflammatory reactions, they have perhaps a far more important role in acting as second messenger systems to maintain normal cell function. It is theperturbations of these reactions which pose the most intriguing therapeutic challenges. This volume deals with various basic mechanisms of free radical processes and injury. The emphasis in each case is on potential therapeutic strategies developing fromthis new knowledge.