Collects Amazing Spider-Man Annual #1 Amazing Spider-Man #334-339. When still in high school, the Amazing Spider-Man faced one of his most chilling challenges when six of his most nerve-wracking nemeses formed the Sinister Six! Years later, Doctor Octopus reunites the team for his most remarkable racket yet, and time has made them deadlier than ever!

The Six have never been more sinister than in this star-studded saga! They've looted and slaughtered their way across an alien world, and Earth is next! If even Spider-Man's strength, wit and new web cannons can't stop the murderous miscreants and their robot army, it may take a dozen heroes to win the day - but one of the Six outweighs and outpowers all of them combined! Guest-starring Ghost Rider, the Incredible Hulk, Deathlok and more! COLLECTING: SPIDER-MAN (1990) 15, 18-23

This first combined edition of the acclaimed Spider-Man/Sinister Six saga, first published by ibook in hardcover in separate editions, features two complete novels in which Doctor Octopus, Electro, the Vulture, Mysterio, and an even more powerful enemy plan to destroy the "Webbed Wonder."

Spiderman must try to save Pity from the predicament she is in at the same time stop the Sinister Six from carrying out the Gentleman's world-threatening plans.

You are Peter Parker, the amazing Spider-Man. On assignment for the "Daily Bugle", you attend a science lecture conducted by Dr. Bruce Banner, the man cursed with turning into the rampaging Hulk whenever he becomes angry! When Banner is kidnapped by a pair of robots, you're the only super hero who can help him.

Doctor Octopus is putting the band back together! But who will join master planner Otto Octavius in the most Sinister Six of all? Spidey is about to find out, but defeating this sextet of his most ruthless foes will test him like never before -- and in the aftermath, Peter's tremendous sense of responsibility will lead him to give up his powers! Is this Spider-Man no more? Normal life isn't so great when the Scorpion attacks, and the Black Cat must leap to the rescue. Fingers crossed that the web-slinger will be back in action by the time Venom returns, the Avengers assemble and Doctor Doom arrives in town! Plus: Peter and Mary Jane's romantic getaway in Scotland turns into a haunted second honeymoon! Collecting AMAZING SPIDER-MAN (1963) #334-350 and SPIDER-MAN: SPIRITS OF THE EARTH.

Doctor Octopus teams up with the Vulture, Electro, Kraven the Hunter, Sandman, and Mysterio in the hopes of bringing down Spider-Man forever.