Major Robert Rogers of the famous Rogers' Rangers wrote the Rules for the Ranging Service in 1757 to instruct selected members of the regular British Army in the techniques of "woods warfare" in North America: ambush, attack, pursuit, retreat, and other t

This is a comprehensive major reference work for our SpringerReference program covering clinical trials. Although the core of the Work will focus on the design, analysis, and interpretation of scientific data from clinical trials, a broad spectrum of clinical trial application areas will be covered in detail. This is an important time to develop such a Work, as drug safety and efficacy emphasizes the Clinical Trials process. Because of an immense and growing international disease burden, pharmaceutical and biotechnology companies continue to develop new drugs. Clinical trials have also become extremely globalized in the past 15 years, with over 225,000 international trials ongoing at this point in time. Principles in Practice of Clinical Trials is truly an interdisciplinary that will be divided into the following areas: 1) Clinical Trials Basic Perspectives 2) Regulation and Oversight 3) Basic Trial Designs 4) Advanced Trial Designs 5) Analysis 6) Trial Publication 7) Topics Related Specific Populations and Legal Aspects of Clinical Trials The Work is designed to be comprised of 175 chapters and approximately 2500 pages. The Work will be oriented like many of our SpringerReference Handbooks, presenting detailed and comprehensive expository chapters on broad subjects. The Editors are major figures in the field of clinical trials, and both have written textbooks on the topic. There will also be a slate of 7-8 renowned associate editors that will edit individual sections of the Reference.

Edited by a professor at Harvard Medical School who has extensive experience in this field, this important and timely book presents a variety of perspectives on the organization of patient medical records around patient problems, presenting a more effective problem-oriented approach rather than the traditional data-oriented approach. It is comprehensive, covering the history and importance of the electronic health record, the attitudes toward and use of problem lists, strategies to improve the problem list, and applications in practice of the problem list.

The increasing relevance of security to real-life applications, such as electronic commerce and Internet banking, is attested by the fast-growing number of - search groups, events, conferences, and summer schools that address the study of foundations for the analysis and the design of security aspects. The “Int- national School on Foundations of Security Analysis and Design” (FOSAD, see http://www.sti.uniurb.it/events/fosad/)has been one of the foremost events - tablishedwiththegoalofdisseminatingknowledgeinthiscriticalarea,especially for young researchers approaching the ?eld and graduate students coming from less-favoured and non-leading countries. The FOSAD school is held annually at the Residential Centre of Bertinoro (http://www.ceub.it/), in the fascinating setting of a former convent and ep- copal fortress that has been transformed into a modern conference facility with computing services and Internet access. Since the ?rst school, in 2000, FOSAD hasattractedmorethan250participantsand50lecturersfromallovertheworld. A collection of tutorial lectures from FOSAD 2000 was published in Springer’s LNCS volume 2171. Some of the tutorials given at the two successive schools (FOSAD 2001 and 2002) are gathered in a second volume, LNCS 2946. To c- tinue this tradition, the present volume collects a set of tutorials fromthe fourth FOSAD, held in 2004, and from FOSAD 2005.