The Role of Zinc Signaling in Alzheimer's Disease
Title | The Role of Zinc Signaling in Alzheimer's Disease PDF eBook |
Author | Chen-Viki Abramovitch-Dahan |
Publisher | |
Pages | 65 |
Release | 2014 |
Genre | Alzheimer's disease |
ISBN |
Zinc Signaling
Title | Zinc Signaling PDF eBook |
Author | Toshiyuki Fukada |
Publisher | Springer Nature |
Pages | 412 |
Release | 2019-12-13 |
Genre | Medical |
ISBN | 9811505578 |
This book, now in an extensively revised second edition, describes the crucial role of zinc signaling in biological processes on a molecular and physiological basis. Global leaders in the field review the latest knowledge, including the very significant advances in understanding that have been achieved since publication of the first edition. Detailed information is provided on all the essentials of zinc signaling, covering molecular aspects and the roles of zinc transporters, the zinc sensing receptor, and metallothioneins. Detection techniques for zinc signals, involving genetically encoded and chemical probes, are also described. The critical contributions of the zinc signal in maintaining health and the adverse consequences of any imbalance in the signal are then thoroughly addressed. Here, readers will find up-to-date information on the significance of the zinc signal in a wide range of conditions, including cardiovascular disorders, neurodegenerative diseases, diabetes, autoimmune diseases, inflammatory conditions, skin disease, osteoarthritis, and cancer. The book will be of value for researchers, clinicians, and advanced students.
Zinc Signals in Cellular Functions and Disorders
Title | Zinc Signals in Cellular Functions and Disorders PDF eBook |
Author | Toshiyuki Fukada |
Publisher | Springer |
Pages | 345 |
Release | 2014-09-25 |
Genre | Science |
ISBN | 443155114X |
This book describes the crucial role of "zinc signals" in biological processes on a molecular and physiological basis, discussing future directions and questions underlying this unique phenomenon. To accomplish this, a group of worldwide leaders in the field, who have made outstanding contributions, overview zinc signals from a professional standpoint. Zinc plays an indispensable role in various cellular processes. It regulates a great number of protein functions including transcription factors, enzymes, adapters, and growth factors as a structural or catalytic factor or both. Recently, another function of zinc has received extensive interest and attention because of its potential importance as a signaling mediator. Zinc plays a dynamic role as an intracellular and extracellular signaling factor and thus regulates cellular signaling pathways, which enables communication between cells, conversion of extracellular stimuli to intracellular signals, and control of various intracellular events. These functions of zinc have become recognized as “zinc signals,” which play critical roles in physiology, and therefore their imbalance can cause a variety of problems with regard to human health. Because the notion of zinc signals is quite new and no integrative review books focusing on them have yet been published, we believe this book will provide very timely information on the subject and thus should be of importance and interest to a wide range of readers.
Therole of Zinc Signaling in Alzheimer's Disease
Title | Therole of Zinc Signaling in Alzheimer's Disease PDF eBook |
Author | Chen-Viki Abramovitch-Dahan |
Publisher | |
Pages | 69 |
Release | 2014 |
Genre | |
ISBN |
The Role of Zinc Transporters in Alzheimer's Disease
Title | The Role of Zinc Transporters in Alzheimer's Disease PDF eBook |
Author | Jennifer Lynn Smith |
Publisher | |
Pages | 282 |
Release | 2007 |
Genre | |
ISBN |
Zinc Signaling in Physiology and Pathogenesis
Title | Zinc Signaling in Physiology and Pathogenesis PDF eBook |
Author | Toshiyuki Fukada |
Publisher | MDPI |
Pages | 293 |
Release | 2018-05-04 |
Genre | Science |
ISBN | 3038428213 |
This book is a printed edition of the Special Issue "Zinc Signaling in Physiology and Pathogenesis" that was published in IJMS
Neurodegenerative Diseases
Title | Neurodegenerative Diseases PDF eBook |
Author | Uday Kishore |
Publisher | BoD – Books on Demand |
Pages | 642 |
Release | 2013-05-15 |
Genre | Medical |
ISBN | 9535110888 |
This book highlights the pathophysiological complexities of the mechanisms and factors that are likely to be involved in a range of neuroinflammatory and neurodegenerative diseases including Alzheimer's disease, other Dementia, Parkinson Diseases and Multiple Sclerosis. The spectrum of diverse factors involved in neurodegeneration, such as protein aggregation, oxidative stress, caspases and secretase, regulators, cholesterol, zinc, microglia, astrocytes, oligodendrocytes, etc, have been discussed in the context of disease progression. In addition, novel approaches to therapeutic interventions have also been presented. It is hoped that students, scientists and clinicians shall find this very informative book immensely useful and thought-provoking.