The complex nature of the relationship between theatre and politics is explored in this study of the Polish theatre scene. It traces the development of the alternative theatre movement from its origins, in the 1950s, through to its decline in the late 1980s.

Made in Poland: Studies in Popular Music serves as a comprehensive introduction to the history, sociology, and musicology of contemporary Polish popular music. Each essay, written by a leading scholar of Polish music, covers the major figures, styles, and social contexts of pop music in Poland and provides adequate context so readers understand why the figure or genre under discussion is of lasting significance. The book first presents a general description of the history and background of popular music in Poland, followed by essays organized into thematic sections: Popular Music in the People’s Republic of Poland; Documenting Change and Continuity in Music Scenes and Institutions; and Music, Identity, and Critique.

The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them. This volume in the History of Toxicology and Environmental Health series explores the history of alternative test development, validation, and use, with an emphasis on humanity and good science, in line with the Three Rs (Replacement,Reduction, Refinement) concept expounded by William Russell and Rex Burch in 1959 in their now classic volume, The Principles of Humane Experimental Technique. The book describes the historical development of technologies that have influenced the application of alternatives in toxicology and safety testing. These range from single cell monocultures to sophisticated, miniaturised and microfluidic organism-on-a-chip devices, and also include molecular modelling, chemoinformatics and QSAR analysis, and the use of stem cells, tissue engineering and hollow fibre bioreactors. This has been facilitated by the wider availability of human tissues, advances in tissue culture, analytical and diagnostic methods, increases in computational processing, capabilities, and a greater understanding of cell biology and molecular mechanisms of toxicity. These technological developments have enhanced the range and information content of the toxicity endpoints detected, and therefore the relevance of test systems and data interpretation, while new techniques for non-invasive diagnostic imaging and high resolution detection methods have permitted an increased role for human studies. Several key examples of how these technologies are being harnessed to meet 21st century safety assessment challenges are provided, including their deployment in integrated testing schemes in conjunction with kinetic modelling, and in specialized areas, such as inhalation toxicity studies. The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them. This volume in the History of Toxicology and Environmental Health series explores the history of alternative test development, validation, and use, with an emphasis on humanity and good science, in line with the Three Rs (Replacement, Reduction, Refinement) concept expounded by William Russell and Rex Burch in 1959 in their now-classic volume, The Principles of Humane Experimental Technique. The book describes the historical development of technologies that have influenced the application of alternatives in toxicology and safety testing. These range from single cell monocultures to sophisticated miniaturised and microfluidic organism-on-a-chip devices, and also include molecular modelling, chemoinformatics and QSAR analysis, and the use of stem cells, tissue engineering and hollow fibre bioreactors. This has been facilitated by the wider availability of human tissues, advances in tissue culture, analytical and diagnostic methods, increases in computational processing capabilities, and a greater understanding of cell biology and molecular mechanisms of toxicity. These technological developments have enhanced the range and information content of the toxicity endpoints detected, and therefore the relevance of test systems and data interpretation, while new techniques for non-invasive diagnostic imaging and high resolution detection methods have permitted an increased role for human studies. Several key examples of how these technologies are being harnessed to meet 21st century safety assessment challenges are provided, including their deployment in integrated testing schemes in conjunction with kinetic modelling, and in specialised areas, such as inhalation toxicity studies.

The complex nature of the relationship between theatre and politics is explored in this study of the Polish theatre scene. It traces the development of the alternative theatre movement from its origins, in the 1950s, through to its decline in the late 1980s.

This book, the first of two volumes, brings together the work of Domenico Mario Nuti to highlight his significant and varied contribution to economics. Bringing together works from across Nuti’s career, his distinctive intellectual framework is exemplified in relation to discussions on the drivers of economic growth and development, the most efficient economic system, the organisation of firms, and how economies should be managed. This volume gives particular attention to socialist economic systems, and the transition of former socialist countries to market economies. This book, through the inclusion of an introduction, aims to contextualise his ideas and illustrate their continued relevance. It will be of wide interest to students and researchers.