In the twenty-first century, the United States confronts an international system of great complexity and shifting security challenges. Among these challenges are those posed by nuclear weapons. Instead of becoming obsolete or being marginalized by the end of the Cold War and the demise of the Soviet Union, nuclear weapons have become more important to present and future international stability and peace but the relationship is paradoxical. On one hand, the spread of nuclear weapons to additional states with unsettled grievances or hegemonic ambitions threatens to destabilize local balances of power and set off regional arms races. In addition, the possible acquisition by terrorists of nuclear weapons or fissile materials creates a threat that may be ’beyond deterrence’ according to hitherto accepted concepts. On the other hand, nuclear weapons in the hands of other states can contribute to stable deterrence and help to prevent nuclear proliferation to international miscreants. Certain cases loom large in the short run that highlight this book’s relevance, including the possible acquisition and deployment of nuclear weapons by Iran and the continuing tensions created by North Korea’s nuclear arsenal. The Obama ’pivot’ of national security and defense emphasis to Asia reflects not only the growing economic importance of that region, but also the growing number of security dilemmas in a region that is already awash in nuclear forces. The management of nuclear crises and even the possible need to terminate nuclear wars before they expand beyond a single region are among the possible challenges facing future U.S. and allied policy makers and military leaders.

In the twenty-first century, the United States confronts an international system of great complexity and shifting security challenges. Among these challenges are those posed by nuclear weapons. Instead of becoming obsolete or being marginalized by the end of the Cold War and the demise of the Soviet Union, nuclear weapons have become more important to present and future international stability and peace but the relationship is paradoxical. On one hand, the spread of nuclear weapons to additional states with unsettled grievances or hegemonic ambitions threatens to destabilize local balances of power and set off regional arms races. In addition, the possible acquisition by terrorists of nuclear weapons or fissile materials creates a threat that may be ‘beyond deterrence’ according to hitherto accepted concepts. On the other hand, nuclear weapons in the hands of other states can contribute to stable deterrence and help to prevent nuclear proliferation to international miscreants. Certain cases loom large in the short run that highlight this book’s relevance, including the possible acquisition and deployment of nuclear weapons by Iran and the continuing tensions created by North Korea’s nuclear arsenal. The Obama ‘pivot’ of national security and defense emphasis to Asia reflects not only the growing economic importance of that region, but also the growing number of security dilemmas in a region that is already awash in nuclear forces. The management of nuclear crises and even the possible need to terminate nuclear wars before they expand beyond a single region are among the possible challenges facing future U.S. and allied policy makers and military leaders.

Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

Non-proliferation concerns have often been shrugged off by nations for short-term and short-sighted strategic interests. The present relationship between Pakistan and the US is a case in point. Though a member of the NPT, coupled with non-proliferation as its foreign policy, the US has been turning a blind eye to Pakistan's long and avid quest for nuclear weapons - primarily to serve its own short-term strategic interests in the region. Pakistan, well aware of this, has exploited the situation to full. The focus of this work is to determine whether the Western experts' apprehensions on the safety and security of Pakistan's nuclear installations and fissile material are well founded or an exaggeration. The decades-old nuclear trade between Pakistan and other countries has also been discussed with a view to highlighting the fact that A. Q. Khan's proliferation linkages did not come as a surprise to the US, emphasizing the point that Washington had been turning a blind eye to the nuclear linkages and programmes for its own strategic interests. The study also holds that NPT has been unsuccessful in controlling nuclear proliferation and suggests ways to curb further proliferation.

Mitochondrial cytopathies are mutations in the inherited maternal mitochondrial genome, or the nuclear DNA-mutation. Mitochondrial respiratory chain disorders (RCD) are a group of genetically and clinically heterogeneous diseases, due to the fact that protein components of the respiratory chain are encoded by both mitochondrial and nuclear genomes and are essential in all cells. In addition, the biogenesis, structure and function of mitochondria, including DNA replication, transcription, and translation, all require nuclear encoded genes. Since mitochondria are present in every cell, every tissue, mitochondrial disorder usually affects multiple organs.

This book examines the importance of global nuclear order, emphasising the importance of perspective in our understanding of it, and its significance in international politics. Addressing a gap in existing literature, this book provides an introduction to nuclear weapon states and their relationship with the global nuclear order/disorder paradigm. It explores four main themes and aims to: 1. conceptualise the dichotomous paradigm of global nuclear order/disorder; 2. outline the different phases of global nuclear order/disorder from 1945 to present; 3. address the Nuclear Non-Proliferation Treaty (NPT) and the wider international nuclear non-proliferation regime; 4. provide an overview of every nuclear weapon state’s national nuclear doctrines throughout the years. The book will be of much interest to students of nuclear proliferation, global governance, security studies, Cold War studies, foreign policy and IR, more generally.

From China's most influential foreign policy thinker, a vision for a "Beijing Consensus" for international relations The rise of China could be the most important political development of the twenty-first century. What will China look like in the future? What should it look like? And what will China's rise mean for the rest of world? This book, written by China's most influential foreign policy thinker, sets out a vision for the coming decades from China's point of view. In the West, Yan Xuetong is often regarded as a hawkish policy advisor and enemy of liberal internationalists. But a very different picture emerges from this book, as Yan examines the lessons of ancient Chinese political thought for the future of China and the development of a "Beijing consensus" in international relations. Yan, it becomes clear, is neither a communist who believes that economic might is the key to national power, nor a neoconservative who believes that China should rely on military might to get its way. Rather, Yan argues, political leadership is the key to national power, and morality is an essential part of political leadership. Economic and military might are important components of national power, but they are secondary to political leaders who act in accordance with moral norms, and the same holds true in determining the hierarchy of the global order. Providing new insights into the thinking of one of China's leading foreign policy figures, this book will be essential reading for anyone interested in China's rise or in international relations.