The Least Likely Man

The Least Likely Man
Title The Least Likely Man PDF eBook
Author Franklin H. Portugal
Publisher MIT Press
Pages 198
Release 2015-02-06
Genre Biography & Autobiography
ISBN 0262028476

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How unassuming government researcher Marshall Nirenberg beat James Watson, Francis Crick, and other world-famous scientists in the race to discover the genetic code. The genetic code is the Rosetta Stone by which we interpret the 3.3 billion letters of human DNA, the alphabet of life, and the discovery of the code has had an immeasurable impact on science and society. In 1968, Marshall Nirenberg, an unassuming government scientist working at the National Institutes of Health, shared the Nobel Prize for cracking the genetic code. He was the least likely man to make such an earth-shaking discovery, and yet he had gotten there before such members of the scientific elite as James Watson and Francis Crick. How did Nirenberg do it, and why is he so little known? In The Least Likely Man, Franklin Portugal tells the fascinating life story of a famous scientist that most of us have never heard of. Nirenberg did not have a particularly brilliant undergraduate or graduate career. After being hired as a researcher at the NIH, he quietly explored how cells make proteins. Meanwhile, Watson, Crick, and eighteen other leading scientists had formed the “RNA Tie Club” (named after the distinctive ties they wore, each decorated with one of twenty amino acid designs), intending to claim credit for the discovery of the genetic code before they had even worked out the details. They were surprised, and displeased, when Nirenberg announced his preliminary findings of a genetic code at an international meeting in Moscow in 1961. Drawing on Nirenberg's “lab diaries,” Portugal offers an engaging and accessible account of Nirenberg's experimental approach, describes counterclaims by Crick, Watson, and Sidney Brenner, and traces Nirenberg's later switch to an entirely new, even more challenging field. Having won the Nobel for his work on the genetic code, Nirenberg moved on to the next frontier of biological research: how the brain works.

The Least Likely Man

The Least Likely Man
Title The Least Likely Man PDF eBook
Author Franklin H. Portugal
Publisher MIT Press
Pages 198
Release 2015-02-13
Genre Biography & Autobiography
ISBN 0262323540

Download The Least Likely Man Book in PDF, Epub and Kindle

How unassuming government researcher Marshall Nirenberg beat James Watson, Francis Crick, and other world-famous scientists in the race to discover the genetic code. The genetic code is the Rosetta Stone by which we interpret the 3.3 billion letters of human DNA, the alphabet of life, and the discovery of the code has had an immeasurable impact on science and society. In 1968, Marshall Nirenberg, an unassuming government scientist working at the National Institutes of Health, shared the Nobel Prize for cracking the genetic code. He was the least likely man to make such an earth-shaking discovery, and yet he had gotten there before such members of the scientific elite as James Watson and Francis Crick. How did Nirenberg do it, and why is he so little known? In The Least Likely Man, Franklin Portugal tells the fascinating life story of a famous scientist that most of us have never heard of. Nirenberg did not have a particularly brilliant undergraduate or graduate career. After being hired as a researcher at the NIH, he quietly explored how cells make proteins. Meanwhile, Watson, Crick, and eighteen other leading scientists had formed the “RNA Tie Club” (named after the distinctive ties they wore, each decorated with one of twenty amino acid designs), intending to claim credit for the discovery of the genetic code before they had even worked out the details. They were surprised, and displeased, when Nirenberg announced his preliminary findings of a genetic code at an international meeting in Moscow in 1961. Drawing on Nirenberg's “lab diaries,” Portugal offers an engaging and accessible account of Nirenberg's experimental approach, describes counterclaims by Crick, Watson, and Sidney Brenner, and traces Nirenberg's later switch to an entirely new, even more challenging field. Having won the Nobel for his work on the genetic code, Nirenberg moved on to the next frontier of biological research: how the brain works.

Concrete Planet

Concrete Planet
Title Concrete Planet PDF eBook
Author Robert Courland
Publisher Rowman & Littlefield
Pages 425
Release 2022-06-21
Genre Science
ISBN 163388869X

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Concrete: We use it for our buildings, bridges, dams, and roads. We walk on it, drive on it, and many of us live and work within its walls. But very few of us know what it is. We take for granted this ubiquitous substance, which both literally and figuratively comprises much of modern civilization's constructed environment; yet the story of its creation and development features a cast of fascinating characters and remarkable historical episodes. Featuring a new epilogue on the Surfside condominium collapse and the current state of infrastructure in America, this book delves into this history, opening readers' eyes at every turn. In a lively narrative peppered with intriguing details, author Robert Courland describes how some of the most famous personalities of history became involved in the development and use of concrete-including King Herod the Great of Judea, the Roman emperor Hadrian, Thomas Edison (who once owned the largest concrete cement plant in the world), and architect Frank Lloyd Wright. Courland points to recent archaeological evidence suggesting that the discovery of concrete directly led to the Neolithic Revolution and the rise of the earliest civilizations. Much later, the Romans reached extraordinarily high standards for concrete production, showcasing their achievement in iconic buildings like the Coliseum and the Pantheon. Amazingly, with the fall of the Roman Empire, the secrets of concrete manufacturing were lost for over a millennium. The author explains that when concrete was rediscovered in the late eighteenth century it was initially viewed as an interesting novelty or, at best, a specialized building material suitable only for a narrow range of applications. It was only toward the end of the nineteenth century that the use of concrete exploded. During this rapid expansion, industry lobbyists tried to disguise the fact that modern concrete had certain defects and critical shortcomings. It is now recognized that modern concrete, unlike its Roman predecessor, gradually disintegrates with age. Compounding this problem is another distressing fact: the manufacture of concrete cement is a major contributor to global warming. Concrete Planet is filled with incredible stories, fascinating characters, surprising facts, and an array of intriguing insights into the building material that forms the basis of the infrastructure on which we depend.

Girl Least Likely To

Girl Least Likely To
Title Girl Least Likely To PDF eBook
Author Liz Jones
Publisher Simon and Schuster
Pages 297
Release 2013-07-04
Genre Biography & Autobiography
ISBN 1471101959

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Liz Jones is Fashion Editor of the Daily Mail, and a columnist for the Mail on Sunday. She is the former editor of Marie Claire, which sounds quite an achievement, but she was sacked three years in. A psychotherapist once told her, 'What you brood on will hatch', and she was right. Nothing Liz ever did in life ever worked out. Nothing. Not one single thing. Liz grew up in Essex, the youngest of seven children. Her mother was a martyr, her dad so dashing that no other man could ever live up to his pressed and polished standards. Her siblings terrified her, with their Afghan coats, cigarettes, parties, sex and drugs. They made her father shout, and her mother cry. Liz became an anorexic aged eleven, an illness that continues to blight her life today. She remained a virgin until her thirties, and even then found the wait wasn't really worth it; it was just one more thing to add to her to do list. She was named Columnist of the Year 2012 by the British Society of Magazine Editors, but is still too frightened to answer the phone, too filled with disgust at her own image to glance in the mirror or eat a whole avocado. She lives alone with her four rescued collies, three horses and seventeen cats. Girl Least Likely Tois the opposite of 'having it all'. It is a life lesson in how NOT to be a woman.

Least Likely Suspect

Least Likely Suspect
Title Least Likely Suspect PDF eBook
Author Cooper McKenzie
Publisher Cooper McKenzie, LLC
Pages 120
Release 2021-06-04
Genre
ISBN 9781737281702

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A mother will do anything to obtain justice for her child. After crashing a holiday party, Samantha Wycoff slips away to the restroom where she stares at her reflection and wonders, "How the hell did I get here?" Six months earlier, her son, Thomas, was beaten so severely he did not recover. Samantha knows his girlfriend, Velvet Flores, is guilty, but with no witnesses and what Samantha knows is a fake alibi, the police and courts can do nothing. Micah Kerrick, Thomas's childhood best friend, offers to help her, but only if she'll join his team of government troubleshooters. A retired schoolteacher slash church lady slash professional volunteer would be the perfect cover for any mission - except one. Will Samantha agree to a career change and join Micah's Misfits? Will Micah's handler allow such an unusual agreement to stand? Or will Samantha find herself facing certain termination?

Becoming Madison

Becoming Madison
Title Becoming Madison PDF eBook
Author Michael Signer
Publisher Public Affairs
Pages 386
Release 2015-03-10
Genre Biography & Autobiography
ISBN 1610392957

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Presents an investigation into the intellectual, psychological, and personal life of the least known Founding Father, shedding light on this leader who pushed the American state to achieve its potential no matter the obstacle.

The Man Most Likely

The Man Most Likely
Title The Man Most Likely PDF eBook
Author Cindi Myers
Publisher Harlequin
Pages 218
Release 2009-05-01
Genre Fiction
ISBN 142683294X

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With her voluptuous, plus-size figure, Angela Krizova knows she doesn't fit the male fantasy of the perfect woman. That's fine, because Bryan Perry isn't her idea of the ideal man, either. The gorgeous ski-bum-turned-corporate-exec is just the type she avoids like the plague. Except he won't take no for an answer. With Bryan pursuing her as if she's the most desirable woman in Crested Butte, Angela's starting to believe it just a little herself. Is the most irresistible guy in town really falling for her? Or is he the man most likely to break her heart?