This is a reference text covering all aspects of renal disease, including: pathology, clinical features, imaging, hypertension, atherosclerotic disease, medical and surgical treatment.

This monograph provides a timely update on the pathophysiology, diagnosis, and therapy of renovascular and renal parenchymatous hypertension. The underlying causes of the most common forms of hypertension are discussed in separate chapters. Special emphasis is laid on newer pathophysiological aspects of the disease, in particular the vascular wall renin-angiotensin system. Furthermore, there is in depth discussion of all the new techniques that are currently available for use in the diagnosis of renal hypertension, e.g., ultrasound and Doppler techniques, magnetic resonance imaging, and nuclear renography. These techniques are discussed by internationally renowned experts in the field. The book also covers topics such as the value of medical therapy, surgical techniques, and percutaneous transluminal angioplasty, with special reference to the treatment of renal hypertension.

Chronic kidney disease is one of the world's major public health problems, and the prevalence of kidney failure is rising steadily. Among the risk factors for a faster progression of renal disease are hypertension and proteinuria, many studies clearly demonstrating that hypertension is both a cause and consequence of chronic kidney disease. Namely, renal blood pressure regulation seems to be involved in five major pathophysiological mechanisms (all closely related to the renin-angiotensin system): Pressure-natriuresis, renal sympathetic nervous system, renal blood flow, intraglomerular pressure and tubuloglomerular feedback. This book reviews experimental data which form the basis of our current understanding of the association between hypertension and kidney diseases: The pathogenesis of increased blood pressure, the mechanisms by which systemic hypertension promotes progressive kidney failure, and the impact of antihypertensive agents on experimental renal mechanisms involved in hypertension. Furthermore, the role of angiotensin II receptor blockers in both the control of systemic blood pressure and the reduction of proteinuria is examined in an attempt to define optimal therapeutic strategies to prevent the otherwise inexorable deterioration of renal function in patients with chronic kidney disease.

Hypertension/high blood pressure affects 1 in every 4 adults in this country. Hypertension is a serious condition that can damage the blood vessels and eventually lead to stroke, heart failure, heart attack, kidney failure and vision problems. Whether you're a newly diagnosed patient, or are a friend or relative of someone suffering from high blood pressure, this book offers help. The only text available to provide both the doctor's and patient's views, 100 Questions & Answers About High Blood Pressure (Hypertension) gives you authoritative, practical answers to your questions. Written by an expert on the subject, with "insider" commentary from actual patients, this book is an invaluable resource for anyone struggling with the medical, psychological, or emotional turmoil of this condition. -- Provided by publisher.

Blood pressure control is central to all bodily functions. There are many points in the multifaceted cybernetic system wherein hypertension may be produced. Hypertension is a 'young' disorder whose existence has been known for less than a century. It is not only extremely prevalent among every popula tion, but also deleterious to the health of mankind. The more we understand about hypertension's harmful effects, the more urgent is the need for its effective control. The kidney is the central organ that controls vascular tone and body fluid volume; these two factors are dominant in determining arterial blood pres sure. Hence, it is not surprising to find in hypertensive disorders that there are abnormalities in the kidneys, functional or anatomical, subtle or overt, that cause or are the consequence of hypertension. The first suggestion that the kidney could cause hypertension was made in 1836, before arterial pressure could even be measured, by Richard Bright. He observed that cardiac hypertrophy was often present in patients who died of renal disease. It was, however, Goldblatt and his colleagues in 1934 who opened the modern era of experimental and clinical research in renal hypertension. Since then, although far from complete, enthusiastic and intensive research efforts have greatly improved our understanding of the nature of renal hypertension.

This new text-a collaborative effort between students and teachers at the University of Wisconsin School of Medicine-provides a unique introductory overview of renal disease, including hypertension and renal transplantation, topics not always covered in other texts. It fully discusses the pathophysiology of renal disorders, using case histories and contemporary data to help you appreciate the mechanisms of these diseases and gain a better understanding of the treatment options available. A consistent chapter format-featuring chapter objectives, key points boxes, and helpful case questions with clinical applications throughout-makes the book user-friendly and easy to reference, while questions at the end of each chapter help you assess your mastery of the material. Discusses significant advances in the field-including those related to pathophysiology of glomerular diseases, electrolyte disorders, renal tubular transport systems, hypertension, transplantation, hereditary diseases, and chronic kidney disease-to keep your knowledge current. Uses a consistent chapter format-featuring chapter objectives, key points boxes, and helpful case questions with clinical applications throughout-to make the book user-friendly and easy to reference. Features questions at the end of each chapter to help you gauge your mastery of the material.