This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

This book constitutes the proceedings of the 10th International Symposium on NASA Formal Methods, NFM 2018, held in Newport News, VA, USA, in April 2018. The 24 full and 7 short papers presented in this volume were carefully reviewed and selected from 92 submissions. The papers focus on formal techniques and other approaches for software assurance, their theory, current capabilities and limitations, as well as their potential application to aerospace, robotics, and other NASA-relevant safety-critical systems during all stages of the software life-cycle.