What do feeling sick and being afraid of strangers have in common? The answer is that these feelings represent a behavioural drive which evolved in our ancestors to combat the most dangerous threat to survival: infection. Behaviour and emotions play pivotal roles in the struggle for good health. When your body is telling your brain that you are sick, you are experiencing survival strategies that developed years ago. Listening to these feelings will allow you to save energy that can be used for recuperation and recovery. Urges of staying still, noticing pain, feeling sorry for yourself, and focusing inward are bodily messages that benefit immune defence. For our forefathers, in whom these strategies evolved, it wasn't enough to change behaviour once sick. Defensive behaviours to be able to avoid infection in the first place were also needed. Thus, tools for detecting illness in others evolved. This is why superficial signs of ill-health, or maybe even the prejudicial idea of a person with a foreign bacterial culture, can cause anxiety and avoidance. Not surprisingly, having a too high or too low sensitivity to inner or outer disease signals is connected to mental as well as somatic disorders. In this book, Mats Lekander explains the science behind perceived health, using Barbie dolls, visual illusions, personal experiences, placebo, hypochondriacs and historical anecdotes. Placed against a back-drop of the latest neuroscience and psychoneuroimmunology he explains why you feel healthy or sick. He describes when he poisoned himself at work and enjoyed it, and why white blood cells and inflammation are key players when our brains trys to guess what is going in our inner worlds. The result is an absorbing and eye-opening book, one that seems so relevant in the current times.

As seen on "CBS This Morning" Worldwide, depression will be the single biggest cause of disability in the next twenty years. But treatment for it has not changed much in the last three decades. In the world of psychiatry, time has apparently stood still...until now with Edward Bullmore's The Inflamed Mind: A Radical New Approach to Depression. A Sunday Times (London) Top Ten Bestseller In this game-changing book, University of Cambridge professor of psychiatry Edward Bullmore reveals the breakthrough new science on the link between depression and inflammation of the body and brain. He explains how and why we now know that mental disorders can have their root cause in the immune system, and outlines a future revolution in which treatments could be specifically targeted to break the vicious cycles of stress, inflammation, and depression. The Inflamed Mind goes far beyond the clinic and the lab, representing a whole new way of looking at how mind, brain, and body all work together in a sometimes misguided effort to help us survive in a hostile world. It offers insights into how we could start getting to grips with depression and other mental disorders much more effectively in the future.

The acute inflammatory response is the body's first system of alarm signals that are directed toward containment and elimination of microbial invaders. Uncontrolled inflammation has emerged as a pathophysiologic basis for many widely occurring diseases in the general population that were not initially known to be linked to the inflammatory response, including cardiovascular disease, asthma, arthritis, and cancer. To better manage treatment, diagnosis, and prevention of these wide-ranging diseases, multidisciplinary research efforts are underway in both academic and industry settings. This book provides an introduction to the cell types, chemical mediators, and general mechanisms of the host's first response to invasion. World-class experts from institutions around the world have written chapters for this introductory text. The text is presented as an introductory springboard for graduate students, medical scientists, and researchers from other disciplines wishing to gain an appreciation and working knowledge of current cellular and molecular mechanisms fundamental to inflammation.

Raj Patel, the New York Times bestselling author of The Value of Nothing, teams up with physician, activist, and co-founder of the Do No Harm Coalition Rupa Marya to reveal the links between health and structural injustices--and to offer a new deep medicine that can heal our bodies and our world. The Covid pandemic and the shocking racial disparities in its impact. The surge in inflammatory illnesses such as gastrointestinal disorders and asthma. Mass uprisings around the world in response to systemic racism and violence. Rising numbers of climate refugees. Our bodies, societies, and planet are inflamed. Boldly original, Inflamed takes us on a medical tour through the human body—our digestive, endocrine, circulatory, respiratory, reproductive, immune, and nervous systems. Unlike a traditional anatomy book, this groundbreaking work illuminates the hidden relationships between our biological systems and the profound injustices of our political and economic systems. Inflammation is connected to the food we eat, the air we breathe, and the diversity of the microbes living inside us, which regulate everything from our brain’s development to our immune system’s functioning. It’s connected to the number of traumatic events we experienced as children and to the traumas endured by our ancestors. It’s connected not only to access to health care but to the very models of health that physicians practice. Raj Patel, the renowned political economist and New York Times bestselling author of The Value of Nothing, teams up with the physician Rupa Marya to offer a radical new cure: the deep medicine of decolonization. Decolonizing heals what has been divided, reestablishing our relationships with the Earth and one another. Combining the latest scientific research and scholarship on globalization with the stories of Marya’s work with patients in marginalized communities, activist passion, and the wisdom of Indigenous groups, Inflamed points the way toward a deep medicine that has the potential to heal not only our bodies, but the world.

NOW A MAJOR MOTION PICTURE STARRING CHLOË GRACE MORETZ A “captivating” (The New York Times Book Review), award-winning memoir and instant New York Times bestseller that goes far beyond its riveting medical mystery, Brain on Fire is a powerful account of one woman’s struggle to recapture her identity. When twenty-four-year-old Susannah Cahalan woke up alone in a hospital room, strapped to her bed and unable to move or speak, she had no memory of how she’d gotten there. Days earlier, she had been on the threshold of a new, adult life: at the beginning of her first serious relationship and a promising career at a major New York newspaper. Now she was labeled as violent, psychotic, a flight risk. What happened? In an “unforgettable” (Elle), “stunningly brave” (NPR), and breathtaking narrative, Susannah tells the astonishing true story of her descent into madness, her family’s inspiring faith in her, and the lifesaving diagnosis that almost didn’t happen. “A fascinating look at the disease that…could have cost this vibrant, vital young woman her life” (People), Brain on Fire is an unforgettable exploration of memory and identity, faith and love, and a profoundly compelling tale of survival and perseverance.

A Powerful Guide for Overcoming the Emotional Challenges of Our Turbulent Times. A rising number of people today are troubled by a phenomenon for which they don’t know there’s a name. This condition is called emotional inflammation—a state not unlike post-traumatic stress disorder, but one that stems from simply living in today’s anxious, overwhelming, and tumultuous world. If you’ve suffered from sleep problems, hyperreactivity, persistent grief, or inescapable worry about the future—especially triggered by the nonstop news cycle—then you’re probably dealing with emotional inflammation. The good news is: there’s something you can do about it. With Emotional Inflammation, general and forensic psychiatrist Dr. Lise Van Susteren joins writer Stacey Colino to present a breakthrough guide to help you become grounded and resilient in these turbulent times. You’ll begin by determining your “reactor type” to better understand how your body and mind respond to stress overload. Then you’ll learn the vital steps of the powerful RESTORE program for recovering inner balance, personal effectiveness, and joy in your life: • Recognize Your Feelings: how to identify, unpack, and learn from difficult emotions • Evaluate Your Triggers: pinpoint what sets you off and how you can moderate your reactivity • Steady Your Body’s Natural Rhythms: keys for restoring your natural, healthy internal equilibrium • Think Yourself into a Safe Space: work with your mind to remain flexible, thoughtful, and adaptable • Obey Your Body: essential self-care practices for diet, exercise, stress management, and more • Reclaim the Gifts of Nature: revitalize your healing connection to the natural world and its awe-inspiring benefits • Exercise Your Power: become an “upstander” who takes effective action from a place of compassion, hope, and love Completing the basics of this method, the authors share key insights on how to personalize RESTORE to fit into your life based on which of the four reactor types you identify with—Nervous, Revved, Molten, or Retreating. You can’t always control the crises and catastrophes that are swirling around you. But that does not mean you’re powerless against the status quo—nor do you need to be at the mercy of the physiological, psychological, and spiritual stress responses inside you. With Emotional Inflammation, you now have an invaluable guide to help you cope with the challenges of a turbulent world, calm your body and mind, and reclaim a sense of peace, purpose, and connection to others.

This guideline provides updated global, evidence-informed recommendations on the intake of free sugars to reduce the risk of NCDs in adults and children, with a particular focus on the prevention and control of unhealthy weight gain and dental caries. The recommendations in this guideline can be used by policy-makers and programme managers to assess current intake levels of free sugars in their countries relative to a benchmark. They can also be used to develop measures to decrease intake of free sugars, where necessary, through a range of public health interventions. Examples of such interventions and measures that are already being implemented by countries include food and nutrition labelling, consumer education, regulation of marketing of food and non-alcoholic beverages that are high in free sugars, and fiscal policies targeting foods and beverages that are high in free sugars. This guideline should be used in conjunction with other nutrient guidelines and dietary goals, in particular those related to fats and fatty acids (including saturated fatty acids and trans-fatty acids), to guide development of effective public health nutrition policies and programmes to promote a healthy diet.