In recent years, a number of chronic diseases have been linked, in some cases definitively, to an infectious etiology: peptic ulcer disease with Helicobacter pylori, cervical cancer with several human papillomaviruses, Lyme arthritis and neuroborreliosis with Borrelia burgdorferi, AIDS with the human immunodeficiency virus, liver cancer and cirrhosis with hepatitis B and C viruses, to name a few. The proven and suspected roles of microbes does not stop with physical ailments; infections are increasingly being examined as associated causes of or possible contributors to a variety of serious, chronic neuropsychiatric disorders and to developmental problems, especially in children. The Infectious Etiology of Chronic Diseases: Defining the Relationship, Enhancing the Research, and Mitigating the Effects, summarizes a two-day workshop held by the Institute of Medicine's Forum on Microbial Threats to address this rapidly evolving field. Participants explored factors driving infectious etiologies of chronic diseases of prominence, identified difficulties in linking infectious agents with chronic outcomes, and discussed broad-based strategies and research programs to advance the field.

In 1949 the U.S. National Cancer Institute (NCI) and the Canadian Department of National Health and Welfare (DNHW) commissioned a film, eventually called Challenge. Science Against Cancer, as part of a major effort to recruit young scientists into cancer research. Both organizations feared that poor recruitment would stifle the development of the field at a time when funding for research was growing dramatically. The fear was that there would not be enough new young scientists to meet the demand, and that the shortfall would undermine cancer research and the hopes invested in it. Challenge aimed to persuade young scientists to think of cancer research as a career. This book is the story of that forgotten film and what it tells us about mid-twentieth century American and Canadian cancer research, educational filmmaking, and health education campaigns. It explores why Canadian and American health agencies turned to film to address the problem of scientist recruitment; how filmmakers turned such recruitment concerns into something they thought would work as a film; and how information officers at the NCI and DNHW sought to shape the impact of Challenge by embedding it in a broader educational and propaganda program. It is, in short, an account of the important, but hitherto undocumented, roles of filmmakers and information officers in the promotion of post-Second World War cancer research.

Chronic Disease in the Twentieth Century challenges the conventional wisdom that the concept of chronic disease emerged because medicine's ability to cure infectious disease led to changing patterns of disease. Instead, it suggests, the concept was constructed and has evolved to serve a variety of political and social purposes. How and why the concept developed differently in the United States, an United Kingdom, and France are central concerns of this work. While an international consensus now exists, the different paths taken by these three countries continue to exert profound influence. This book seeks to explain why, among the innumerable problems faced by societies, some problems in some places become viewed as critical public issues that shape health policy. -- from back cover.

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.

Autoimmune and chronic illness are a global crisis, with an estimated 50 million sufferers in the US alone. While modern medicine has drastically reduced overall mortality rates--from heart disease, stroke, HIV, and even cancer--what is fueling this twenty-first century pandemic? In this eye-opening, provocative book, Steven Phillips, MD, and his former patient, singer/songwriter Dana Parish, take on the medical establishment. Backed by a trove of published data, Chronic reveals striking evidence that a broad range of microbes, including the Lyme bacteria, cause a variety of recurrent conditions and autoimmune diseases. Chronic delves into the history and science behind common infections that are difficult to diagnose and treat, debunks widely held beliefs by doctors and patients alike, reveals how medicine got the facts patently wrong, and provides solutions that empower readers to get their lives back. Dr. Phillips was already an internationally renowned physician specializing in complex, chronic diseases when he became a patient himself. After nearly dying from his own mystery illness, he experienced firsthand the medical community's ignorance about the pathogens that underlie a range of chronic conditions--from fibromyalgia, lupus, multiple sclerosis, chronic fatigue syndrome, and rheumatoid arthritis to depression, anxiety, and neurodegenerative disorders. Parish, too, watched her health spiral after twelve top doctors missed an underlying infection that caused heart failure and other sudden, debilitating physical and psychiatric symptoms. Now, they've come together with a mission: to change the current model of simply treating symptoms, often with dangerous, lifelong drugs, and shift the focus to finding and curing root causes of chronic diseases that affect millions around the world.

Written specifically for non-infectious disease specialists in both inpatient and outpatient settings, A Rational Approach to Clinical Infectious Diseases provides concise, practical guidance that mimics the decision-making process and reasoning employed by an ID physician. Using clear, understandable language, Dr. Zelalem Temesgen and his esteemed colleagues at the Mayo Clinic present the art and the context of infectious diseases together with the science, helping non-specialists apply a rational approach to the diagnosis and treatment of infectious conditions. - Clearly explains the rationale of opting for one particular treatment or length of course over another in order to arrange appropriate management and follow-up. - Provides focused ID decision support to questions such as: - What diagnostic test should I order? - What is the correct antibiotic for this patient/geographical region? - Are IV or oral antibiotics most appropriate? - How long should the antibiotic course be and when should it be de-escalated? - What special considerations should be taken in immunocompromised patients? - How often should complex infections be followed up? - Uses a succinct, easy-to-read writing style, following a consistent format: Important characteristics/epidemiology; Clinical related data; Rash characteristics; Ancillary diagnostic studies; Treatment; and Other. - Provides visual and quick-reference support with dozens of figures and tables throughout the text. - Contains invaluable guidance to help non-specialists provide the best care for patients, stem antibiotic misuse and resistance, avoid adverse drug events, and avoid unnecessary costs.