This 1791 four-volume English translation of a key text of Islamic law illuminates the East India Company's legal provision.

The Hidayah has dominated the field of Islamic jurisprudence since the day it was written over 800 years ago. It has been the primary text used by Muslims jurist to issue authentic and reliable rulings on Islamic law according to the school of Imam Abu Hanifa (d 150H/767CE). The Hidayah commands such an authoritative position amongst the doctors of law that the knowledge of a scholar who has not read it is not considered reliable. It has been a standard text in the curricula of Islamic law schools since the 12th century. It was first translated into English by Charles Hamilton in 1791. Around 70 huge commentaries, some spread over more than a dozen volumes have been written on it. The number of explanatory glosses is in thousands. Comprehensive in content and conveniently organized, with the publication of this all previous works that discussed Islamic jurisprudence according to the Hanafi law become outmoded and soon fell into disuse. If revealed books are not taken into account, never has a book received so much attention as the Hidayah. This landmark publication of the Hidayah not only has been translated in its entirety for the first time but has been done so from Arabic, the language in which it was written. The author, Shaykh Al Islam, Burhan Al-Din Marghanani (d 593 AH/ 1197 CE) was considered to be the leading jurist of the Muslim world in his times. "The hidayah is justly celebrated as the most practical and useful summary compilation of Hanafi jurisprudence. It has been a standard text in the curricula of Islamic law schools since the 12th century. It was first translated by Charles Hamilton in 1791. A new translation into modern English has been long overdue. This translation by Imran Ahsan Khan Nyazee is both precise and straight forward. With his knowledge of Islamic law and jurispudence combined with his command of both the Arabic and English languages, he has conveyed the meaning of the original with great clarity. The hidayah is a dense work, intended for use in teaching Hanafi fiqh - it is a work that needs explication if its arguments are to be understood fully. This the translator has provided through this valuable notes" Dr Mohammad Akram Nadwi, research fellow, Oxford centre for Islamic studies, Oxford

Knowledge of pharmacokinetics is critical to understanding the absorption, distribution, metabolism, and excretion of drugs. It is therefore vital to those engaged in the discovery, development, and preclinical and clinical evaluation of drugs, as well as practitioners involved in the clinical use of drugs. Using different approaches accessible to a wide variety of readers, Basic Pharmacokinetics: Second Edition demonstrates the quantitative pharmacokinetic relations and the interplay between pharmacokinetic parameters. After a basic introduction to pharmacokinetics and its related fields, the book examines: Mathematical operations commonly used in pharmacokinetics Drug distribution and clearance and how they affect the rate of drug elimination after a single dose Factors affecting drug absorption following extravascular drug administration, the rate and extent of drug absorption, and drug bioequivalence The steady-state concept during constant rate intravenous infusion and during multiple drug administration Renal drug elimination, drug metabolism, multicompartment models, nonlinear pharmacokinetics, and drug administration by intermittent intravenous infusion Pharmacokinetic-pharmacodynamic modeling, noncompartmental pharmacokinetic data analysis, clearance concept from the physiological point of view, and physiological modeling Clinical applications of pharmacokinetics, including therapeutic drug monitoring, drug pharmacokinetics in special populations, pharmacokinetic drug-drug interactions, pharmacogenomics, and applications of computers in pharmacokinetics Accompanying the book is a CD-ROM with self-instructional tutorials and pharmacokinetic and pharmacokinetic-pharmacodynamic simulations, allowing visualization of concepts for enhanced comprehension. This learning tool received an award from the American Association of Colleges of Pharmacy for innovation in teaching, making it a valuable supplement to this essential text.

From the head writer of the original In Treatment, an exquisite novel of the maturation of a girl, a family, and an entire community Eden is no paradise: it is the stifling, rural community in which upscale urban escapees, Alona and Mark, drift apart and divorce under the resentful scrutiny of Roni, Mark's needy adolescent daughter. Against a rich panorama of Eden's oldtimers and newcomers, Mark, an emotionally detached architect, begins an involvement with his ex-wife's best friend, Dafna, who is desperately trying to conceive through the torments of technology, while sixteen-year-old Roni pursues the attention of older men by readily dispensing sexual favors. Over the course of one month, Roni's self-dramatizing turns to tragedy, her parents are jolted out of their absorbing concerns, and a new family structure begins to form out of an unlikely set of characters. Through a portrait of family entanglements, disappearing countryside, and disappointed expectations, Yael Hedaya, a determinedly plainspoken novelist, has brilliantly mapped the social and emotional ecology of midlife and achieved miracles of insight and understanding.