National Bestseller National Book Critics Circle Award Nominee From the Pulitzer Prize–winning author of The Overstory and the forthcoming Bewilderment, a magnificent double love story of two young couples separated by a distance of twenty-five years. “The most lavishly ambitious American novel since Gravity’s Rainbow . . . An outright marvel.” —Washington Post Stuart Ressler, a brilliant young molecular biologist, sets out in 1957 to crack the genetic code. His efforts are sidetracked by other, more intractable codes—social, moral, musical, spiritual—and he falls in love with a member of his research team. Years later, another young man and woman team up to investigate a different scientific mystery: Why did the eminently promising Ressler suddenly disappear from the world of science? Strand by strand, these two love stories twist about each other in a double helix of desire. The critically acclaimed third novel from Pulitzer Prize–winning author Richard Powers, The Gold Bug Variations is an intellectual tour-de-force that probes the meaning of love, science, music, and art.

ORIGINAL SIN Piers Rameau, a brilliant geneticist, was offered the chance to help design mankind's replacement--Original Man, a smarter, stronger, swifter race based on manipulated human DNA. But Rameau refused, and chose to follow his own path. Now Kuno Gunnarsson, creator of Original Man and Rameau's would-be employer, is dead--but his superior creation lives on. And one faction of Original Man is determined to wrest control of the galaxy from the inferior race. A brutal attack destroys both Rameau's home planet and the satellite that has become his world. One tragic casualty is Dakini, a fragile, genetically altered dancer who had become Rameau's reason to live. The sole survivor, he finds himself a prisoner of Gunnarsson Prime, a clone of the original creator, on board the Jumpship Langstaff. Against his will, Rameau is enlisted as the ship's wartime medical officer. As a doctor, he swore an oath to do no harm. As a man, he swears blood vengeance on the inhuman killers who destroyed everything he ever loved . . . .

Mike Knight, an executive in a semiconductor firm, learns that his eight-year-old son Tim has a rare form of brain cancer. Tim's best hope for long-term survival is a drug called Supragrel. Unfortunately, Supragrel is still in early clinical trials and may reach the market too late. Mike makes the agonizing decision to quit his job and go to work for Altus Labs, the developer of Supragrel, in hopes of helping them bring the drug to market more quickly. Mike is in for the challenge of his life as he struggles to keep his family together while racing against time to implement world-class project management in Altus Labs. Critical Chain Project Management is a superior project management process that has been quietly implemented in some of the world's best-known companies for over a decade. This book tells you the story of a Critical Chain Project Management implementation. The venue is a major pharmaceutical company, but it could happen anywhere in corporate America.

T.H. Huxley led a fascinating and outgoing life. He did battle with God and Gladstone, sat on royal commissions and campaigned for elementary education. He carried Darwin's fight to the public. This book uses the life of Huxley to illustrate the second half of the 19th century.

Lorelei of the Red Mist: Planetary Romances is the companion volume to Martian Quest: The Early Brackett, a volume that collected the First twenty published stories by the ?undisputed Queen of ?Space Opera.? ?With the stories in this volume, Brackett takes the foundation of the Fictional universe established in her early work, and populates these worlds with colorful characters and locales teeming with adventure and intrigue. Here, hard-bitten and cynical rogues risk (and sometimes lose) all to battle stellar horrors, escape from decadent tyrannies, and yes, rescue the girl.During the timeframe when these stories were written, Brackett First broke into writing screenplays for Hollywood. With only modest success for Republic Pictures, it was on the strength of her First mystery novel that she was offered to co-author the screenplay for Warner Bros.? The Big Sleep with William Faulkner by director Howard Hawks.Appropriately, Lorelei of the Red Mist: Planetary Romances features an introduction by a protege of Leigh Brackett, a one-time collaborator (on this volume?s title story) and 2004 recipient of the National Medal of Arts, Ray Bradbury.