The Biological Sciences are in the midst of a scientific rev olution. During the past decade under the rubric of molecu lar biology, chemistry and physics have assumed an integral role in biological research. This is especially true in ge netics, where the cloning of genes and the manipulation of genomic DNA have become in many organisms routine laboratory procedures. These noteworthy advances, it must be empha sized, especially in molecular genetics, are not autonomous. Rather, they have been accomplished with those organisms whose formal genetics has been documented in great detail. For the beginning student or the established investigator who is interested in pursuing eukaryote molecular genetic re search, Drosophila melanogaster, with its rich body of formal genetic information is one organism of choice. The book "Drosophila Genetics. A Practical Course" is an indispens able source of information for the beginner in the biology and formal genetics of Drosophila melanogaster. The scope of this guide, a revision and enlargement of the original German language version, is broad and instructive. The information included ranges from the simple, but necessary, details on how to culture and manipulate Drosophila flies to a series of more sophisticated genetic experiments. After completing the experiments detailed in the text, all students - neophyte or experienced - will be richly rewarded by having acquired a broad base of classical genetics information relevant for the biologist in its own right and prerequisite to Drosophila genetics research - formal and/or molecular. Davis, California, Melvin M.

Dedicated to the memory of George Lefevre in recognition of his exhaustive cytogenetic analysis of the X chromosome, The Genome of Drosophila melanogaster is the complete compendium of what is known about the genes and chromosomes of this widely used model organism. The volume is an up-to-date revision of Lindsley and Grell's 1968 work, Genetic Variations of Drosophila melanogaster. The new edition contains complete descriptions of normal and mutant genes including phenotypic, cytological, molecular, and bibliographic information. In addition, it describes thousands of recorded chromosome rearrangements used in research on Drosophila. This handbook and its accompanying polytene chromosome maps, are sturdily bound into the book as foldouts and available as a separate set, are essential research tools for the Drosophila community. - Describes phenotype, cytology, and molecular biology of all recorded genes of Drosophila melanogaster, plus references to the literature - Describes normal chromosome complement, special chromosome constructs, transposable elements, departures from diploidy, satellite sequences, and nonchromosomal inheritance - Describes all recorded chromosome rearrangements of Drosophila melanogaster as of the end of 1989 Contains the cytogenetic map of all genes as of mid-1991 - Contains the original polytene maps of C.B. Bridges, plus G. Lefevre's photographic equivalents, and the detailed maps of the chromosome arms produced by C.B. and P.M. Bridges - All maps are reprinted as high-quality foldouts sturdily bound into the volume - Maps may also be purchased separately in an eight-map packet, for laboratory and student use

A second edition of the classic handbook has become a standard in the Drosophila field. This edition is expanded to include topics in which classical genetic strategies have been augmented with new molecular tools. Included are such new techniques as homologous recombination, RNAi, new mapping techniques, and new mosaic marking techniques.

Biology of Drosophila was first published by John Wiley and Sons in 1950. Until its appearance, no central, synthesized source of biological data on Drosophila melanogaster was available, despite the fly's importance to science for three decades. Ten years in the making, it was an immediate success and remained in print for two decades. However, original copies are now very hard to find. This facsimile edition makes available to the fly community once again its most enduring work of reference.

"One of the most productive of all laboratory animals, Drosophila has been a key tool in genetics research for nearly a century. At the center of Drosophila culture from 1910 to 1940 was the school of Thomas Hunt Morgan and his students Alfred Sturtevant and Calvin Bridges, who, by inbreeding fruit flies, created a model laboratory creature - the 'standard' fly. By examining the material culture and working customs of Morgan's research group, [the author] brings to light essential features of the practice of experimental science. [This book] takes a broad view of experimental work, ranging from how the fly was introducted into the laboratory and how it was physically redesigned for use in genetic mapping, to how the 'Drosophilists' organized an international network for exchanging fly stocks that spread their practices around the world"--Back cover.

A comprehensive portrayal of the behaviour genetics of the fruit fly (Drosophila melanogaster) and the methods used in these studies.