This book provides a comprehensive overview of the use of PET and SPECT in the classic psychiatric disorders such as depression, bipolar disorder, anxiety disorders, and schizophrenia. In addition, it discusses the application of these functional neuroimaging techniques in a variety of other conditions, including sleep disorders, eating disorders, autism, and chronic fatigue syndrome. The new edition has been extensively revised and updated to reflect the latest advances and results in nuclear imaging within the field. Most chapters are written jointly by a clinical psychiatrist and a nuclear medicine expert to ensure a multidisciplinary approach. This state of the art compendium will be of value for all who have an interest in the field of neuroscience, from psychiatrists and radiologists/nuclear medicine specialists to interested general practitioners and cognitive psychologists. Companion volumes on the use of PET and SPECT in neurology and for the imaging of neurobiological systems complete a trilogy.

New neuroimaging techniques are developing at a break neck pace-every academic journal contains glossy pictures of brain activity corresponding to a particular task emblazoned in glorious technicolor. Discoveries about brain function in psychiatric disorders have been made at an equally rapid rate. However, most books on the subject have been writt

This comprehensive colour atlas provides a state-of-the-art view of Single Photon Emission Computerised Tomography (SPECT) in relation to its application in the fields of nuclear medicine and psychiatry. The broad range of topics covered by experts in the fields of nuclear medicine, neurology and psychiatry from all over the world, reflects the most recent evolution in functional neuroimaging with clinical neuropsychiatric sciences. The book is organised with respect to clinical indication, which implies that whenever possible methodological problems related to clinical indication are categorised under the relevant topic. It is designed to stimulate discussion of some issues of paramount importance for the present and future development of this interdisciplinary modality for the study of patients with diseases of the central nervous system. This textbook is an important tool to all nuclear physicians, neurologists and psychiatrists and will serve as a guide towards the optimal application of SPECT in diagnosis, study of pathophysiology and therapeutic follow-up in neuropsychiatric illnesses.

Functional imaging has the capability to reveal changes in the pathophysiology of tissues and organ systems, mapping the progression and severity of disease, uptake of drugs, and the recovery of tissues following trauma, disease episodes or surgery. In this authoritative new work, leading specialists in neurology and neuroimaging present an update

Recent explorations in the neurosciences have been progressing towards an understanding of the relationship between brain struc ture and brain function. Having passed through an era which may be described as one of a localisationist philosophy, in which discrete brain areas were seen to subserve only discrete functions, the perspective of brain-behaviour relationships has advanced in recent years to an appreciation that a more holistic approach is not only heuristically valid, but is also most likely to lead to future advances. The close relationship between the mind and the brain has been appreciated since the time of Hippocrates when he opined 'men ought to know that from nothing else but thence [from the brain] comes joys, delights, laughter and sports, and sorrows, griefs, despondency and lamentations ... and by this same organ we become mad and delirious and fears and terrors assail us'. In the nineteenth century, particularly in France and Germany, descrip tions of what are now recognised to be independent neurological diseases emerged following empirical clinical observations. Investi gation led to the identification in many cases of underlying struc tural abnormalities which could be linked to pathological changes.

An up-to-date, superbly illustrated practical guide to the effective use of neuroimaging in the patient with sleep disorders. The only book to date to provide comprehensive coverage of this topic. A must for all healthcare workers interested in understanding the causes, consequences and treatment of sleep disorders.