The Development of a Standardized Animal Maze
Title | The Development of a Standardized Animal Maze PDF eBook |
Author | Lucien Hynes Warner |
Publisher | |
Pages | 490 |
Release | 1927 |
Genre | Animal intelligence |
ISBN |
Improving the Utility and Translation of Animal Models for Nervous System Disorders
Title | Improving the Utility and Translation of Animal Models for Nervous System Disorders PDF eBook |
Author | Institute of Medicine |
Publisher | National Academies Press |
Pages | 111 |
Release | 2013-04-25 |
Genre | Medical |
ISBN | 0309266335 |
Nervous system diseases and disorders are highly prevalent and substantially contribute to the overall disease burden. Despite significant information provided by the use of animal models in the understanding of the biology of nervous system disorders and the development of therapeutics; limitations have also been identified. Treatment options that are high in efficacy and low in side effects are still lacking for many diseases and, in some cases are nonexistent. A particular problem in drug development is the high rate of attrition in Phase II and III clinical trials. Why do many therapeutics show promise in preclinical animal models but then fail to elicit predicted effects when tested in humans? On March 28 and 29, 2012, the Institute of Medicine Forum on Neuroscience and Nervous System Disorders convened the workshop "Improving Translation of Animal Models for Nervous System Disorders" to discuss potential opportunities for maximizing the translation of new therapies from animal models to clinical practice. The primary focus of the workshop was to examine mechanisms for increasing the efficiency of translational neuroscience research through discussions about how and when to use animal models most effectively and then best approaches for the interpretation of the data collected. Specifically, the workshop objectives were to: discuss key issues that contribute to poor translation of animal models in nervous system disorders, examine case studies that highlight successes and failures in the development and application of animal models, consider strategies to increase the scientific rigor of preclinical efficacy testing, explore the benefits and challenges to developing standardized animal and behavioral models. Improving the Utility and Translation of Animal Models for Nervous System Disorders: Workshop Summary also identifies methods to facilitate development of corresponding animal and clinical endpoints, indentifies methods that would maximize bidirectional translation between basic and clinical research and determines the next steps that will be critical for improvement of the development and testing of animal models of disorders of the nervous system.
Methods of Behavior Analysis in Neuroscience
Title | Methods of Behavior Analysis in Neuroscience PDF eBook |
Author | Jerry J. Buccafusco |
Publisher | CRC Press |
Pages | 341 |
Release | 2000-08-29 |
Genre | Medical |
ISBN | 1420041819 |
Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic
Archives of Psychology
Title | Archives of Psychology PDF eBook |
Author | Robert Sessions Woodworth |
Publisher | |
Pages | 506 |
Release | 1927 |
Genre | Psychology |
ISBN |
A Field Study of the Chimpanzee
Title | A Field Study of the Chimpanzee PDF eBook |
Author | Henry Wieghorst Nissen |
Publisher | |
Pages | 402 |
Release | 1931 |
Genre | Chimpanzees |
ISBN |
Learning
Title | Learning PDF eBook |
Author | Jerome Frieman |
Publisher | SAGE Publications |
Pages | 609 |
Release | 2015-07-29 |
Genre | Psychology |
ISBN | 1483359220 |
Learning: A Behavioral, Cognitive, and Evolutionary Synthesis by Jerome Frieman and Steve Reilly provides an integrated account of the psychological processes involved in learning and conditioning and their influence on human behavior. With a skillful blend of behavioral, cognitive, and evolutionary themes, the text explores various types of learning as adaptive specialization that evolved through natural selection. Robust pedagogy and relevant examples bring concepts to life in this unique and accessible approach to the field.
Purposive Behavior in Animals and Men
Title | Purposive Behavior in Animals and Men PDF eBook |
Author | Edward Chace Tolman |
Publisher | Univ of California Press |
Pages | 484 |
Release | |
Genre | |
ISBN |