This book provides a detailed update on our knowledge of dental pulp and regenerative approaches to therapy. It is divided into three parts. The pulp components are first described, covering pulp cells, extracellular matrix, vascularization and innervation as well as pulp development and aging. The second part is devoted to pulp pathology and includes descriptions of the differences between reactionary and reparative dentin, the genetic alterations leading to dentinogenesis imperfecta and dentin dysplasia, the pulp reaction to dental materials, adverse impacts of bisphenol A and the effects of fluorosis, dioxin and other toxic agents. The final part of the book focuses on pulp repair and regeneration. It includes descriptions of various in vitro and in vivo (animal) experimental approaches, definition of the pulp stem cells with special focus on the stem cell niches, discussion of the regeneration of a living pulp and information on new strategies that induce pulp mineralization.

"Nearly three decades ago, Samuel Seltzer and I. B. Bender pioneered the concept of developing biologically based recommendations for the clinical practice of endodontics and restorative dentistry. This concept was the cornerstone of their classic textbook, The Dental Pulp. Seltzer and Bender's Dental Pulp represents the evolution of that book and of the philosophical principles on which it was based. Today we know that pulp tissue plays a central role in both local and systemic health. This book presents the latest research on the dental pulp and its interaction with other tissues. Each chapter provides an introduction to its major themes for the busy clinician or dental student, as well as a set of biologically based clinical recommendations for restorative and endodontic procedures. "--Publisher.

Stem cell technology is moving forward at a tremendous rate. Recent discoveries have surprised even the most expert researchers. While every piece of new data broadens the current knowledge and contributes to this moving forward, the new data also serve as paradigm shifters of fundamental knowledge of cell biology. While the question ‘What is a Stem Cell’ may now seem to basic to even discuss, there are still some discrepancies, however, between groups in terms of their functional roles. Teeth develop from the ectoderm of the first branchial arch and the ectomesenchyme of the neural crest. Deciduous teeth start to form between the sixth and eighth weeks, and permanent teeth begin to form in the twentieth weeks. Several studies have demonstrated that the pulp from both adult teeth and deciduous teeth contains dental pulp stem cells. Several factors have made them very attractive as a model system for many researchers; they are multipotent, ethically and non-controversially available in large numbers, immuno-compatible, developmentally primitive, easy to isolate and have high expansion potential in vitro. However, many controversies still exist in the field. There are several unanswered questions in the biology of dental pulp and odontoblasts. This new volume in the SpringerBriefs in Stem Cells series presents an evaluation of stem cells from human dental pulp as a reliable stem cell source for cell-based therapy to stimulate tissue regeneration.​

A unique, multidisciplinary manual for the treatment of pediatric dental emergencies for general practitioners and non-pediatric specialists Management of Dental Emergencies in Children and Adolescents presents the diagnostic skills, treatment options, and management strategies necessary to provide effective and appropriate dental care for children and adolescents. This authoritative manual helps dental practitioners manage potentially stressful situations with children and adolescents while improving their competence in a wide range of urgent pediatric situations. An emphasis on managing the therapeutic demands of both younger patients and their parents enables readers to have greater confidence in handling demanding emergency situations in daily practice. An expert team of contributors explain how to manage tooth substance loss, endodontic problems in deciduous teeth, the long‐term consequences of early tooth loss, the dental issues related to oral health, and more. Guiding practitioners through the unique challenges of pediatric dental emergencies, this book: Explains the differences in treating and managing dental emergencies in children compared to adults Covers all types of pediatric dental emergencies including open pulp in permanent and deciduous teeth, missing teeth, and non-infective dental conditions Offers clinical vignettes and photographs to highlight clinical relevance Includes chapters by experts in multiple disciplines such as endodontics, restorative dentistry, pediatric dentistry, prosthodontics, and orthodontics The first textbook to focus exclusively on young patients in need of acute dental care, Management of Dental Emergencies in Children and Adolescents is a much-needed resource for general and specialist dentists as well as trainee and specialist pediatric dentists.

The definitive endodontics reference, Cohen's Pathways of the Pulp is known for its comprehensive coverage of leading-edge information, materials, and techniques. It examines all aspects of endodontic care, from preparing the clinician and patient for endodontic treatment to the role the endodontist can play in the treatment of traumatic injuries and to the procedures used in the treatment of pediatric and older patients. Not only does Hargreaves and Cohen's 10th edition add five chapters on hot new topics, it also includes online access! As an Expert Consult title, Cohen's Pathways of the Pulp lets you search the entire contents of the book on your computer, and includes five online chapters not available in the printed text, plus videos, a searchable image collection, and more. For evidence-based endodontics research and treatment, this is your one-stop resource!