Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.

Some people suffer from chronic, debilitating disorders for which no conventional treatment brings relief. Can marijuana ease their symptoms? Would it be breaking the law to turn to marijuana as a medication? There are few sources of objective, scientifically sound advice for people in this situation. Most books about marijuana and medicine attempt to promote the views of advocates or opponents. To fill the gap between these extremes, authors Alison Mack and Janet Joy have extracted critical findings from a recent Institute of Medicine study on this important issue, interpreting them for a general audience. Marijuana As Medicine? provides patientsâ€"as well as the people who care for themâ€"with a foundation for making decisions about their own health care. This empowering volume examines several key points, including: Whether marijuana can relieve a variety of symptoms, including pain, muscle spasticity, nausea, and appetite loss. The dangers of smoking marijuana, as well as the effects of its active chemical components on the immune system and on psychological health. The potential use of marijuana-based medications on symptoms of AIDS, cancer, multiple sclerosis, and several other specific disorders, in comparison with existing treatments. Marijuana As Medicine? introduces readers to the active compounds in marijuana. These include the principal ingredient in Marinol, a legal medication. The authors also discuss the prospects for developing other drugs derived from marijuana's active ingredients. In addition to providing an up-to-date review of the science behind the medical marijuana debate, Mack and Joy also answer common questions about the legal status of marijuana, explaining the conflict between state and federal law regarding its medical use. Intended primarily as an aid to patients and caregivers, this book objectively presents critical information so that it can be used to make responsible health care decisions. Marijuana As Medicine? will also be a valuable resource for policymakers, health care providers, patient counselors, medical faculty and studentsâ€"in short, anyone who wants to learn more about this important issue.

This book is the first to present an extensive analysis of the international evidence for the similarities of the consumption patterns of such controversial commodities as alcohol, tobacco and marijuana, using recent data from a number of developed and less developed countries over a number of years. The book also presents analysis of the consumption patterns of food in general and soft drinks in particular. In addition the book provides a detailed analysis of the consumption restrictions and regulations in place in various countries in relation to issues associated with taxation, availability, and marketing of these products. The book's focus is on rigorous empirical analysis and presents the estimates of demand elasticities of these five commodities across different countries. Such estimates are key inputs for government economic models that are used for the purpose of social policy analysis. Furthermore, the book presents hypothesis testing results on various demand theory hypotheses such as demand homogeneity and Slutsky symmetry.

The medical use of marijuana is surrounded by a cloud of social, political, and religious controversy, which obscures the facts that should be considered in the debate. This book summarizes what we know about marijuana from evidence-based medicineâ€"the harm it may do and the relief it may bring to patients. The book helps the reader understand not only what science has to say about medical marijuana but also the logic behind the scientific conclusions. Marijuana and Medicine addresses the science base and the therapeutic effects of marijuana use for medical conditions such as glaucoma and multiple sclerosis. It covers marijuana's mechanism of action, acute and chronic effects on health and behavior, potential adverse effects, efficacy of different delivery systems, analysis of the data about marijuana as a gateway drug, and the prospects for developing cannabinoid drugs. The book evaluates how well marijuana meets accepted standards for medicine and considers the conclusions of other blue-ribbon panels. Full of useful facts, this volume will be important to anyone interested in informed debate about the medical use of marijuana: advocates and opponents as well as policymakers, regulators, and health care providers.

Cannabis is globally the most commonly used psychoactive substance under international control. In 2013 an estimated 181.8 million people aged 15-64 years used cannabis for nonmedical purposes globally (UNODC 2015). There is an increasing demand for treatment for cannabis-use disorders and associated health conditions in high- and middle-income countries. This report focuses on nonmedical use of cannabis building on contributions from a broad range of experts and researchers from different parts of the world. It aims to present current knowledge on the impact of nonmedical cannabis use on health from its impact on brain development to its role in respiratory diseases. The potential medical utility of cannabis - including the pharmacology toxicology and possible therapeutic applications of the cannabis plant - is outside the scope of this report.

From the leading authority on marijuana—a man who has served as White House advisor on drugs to three different administrations and who NBC News once called “the prodigy of drug politics"—comes the remarkable and shocking exposé about how 21st century pot, today’s new and highly potent form of the drug, is on the rise, spreading rapidly across America by an industry intent on putting rising profits over public health. Smokescreen: What the Marijuana Industry Doesn't Want You to Know examines the inside story behind the headlines, containing accounts from Sabet’s time in the Obama administration to stunning revelations from whistleblowers speaking out for the first time. What it finds is how the marijuana industry is running rampant without proper oversight, leaving Americans’ health seriously at risk. Included are interviews with industry insiders who reveal the hidden dangers of a product they had once worshipped. Also contained in these pages are insights from a major underground-market dealer who admits that legalization is hastening the growth of the illicit drug trade. And more to the heart of the issue are the tragic stories of those who have suffered and died as a result of marijuana use, and in many cases, as a result of its mischaracterization. Readers will learn how power brokers worked behind the scenes to market marijuana as a miracle plant in order to help it gain widespread acceptance and to set the stage for the lucrative expansion of recreational pot. The author of this compelling first-person narrative leading the national fight against the legalization of cannabis through his nonprofit, Smart Approaches to Marijuana (aka SAM) is Kevin Sabet. As a policy advisor to everyone from county health commissioners to Pope Francis, and a frequent public speaker on television, radio and through other media outlets, his analysis is consistently relied upon by those who recognize what’s at stake as marijuana lobbyists downplay the risks of massive commercialization. A book several years in the making, filled with vivid characters and informed by hundreds of interviews and scores of confidential documents, Sabet's Smokescreen lays bare the unvarnished truth about marijuana in America.