This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Presents information about the circulatory system, looking at the heart, blood, and blood vessels that compose it, as well as how they work together to keep the body healthy.

How does blood move around inside the human body? Students will learn all about the heart, blood cells, blood vessels, and other important parts of the circulatory system.

Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.

The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. The contributions cover a wide range of topics, from the preprocessing of clinical data to the development of mathematical equations, their numerical solution, and both in-vivo and in-vitro validation. They discuss the flow in the systemic arterial tree and the complex electro-fluid-mechanical coupling in the human heart. Many examples of patient-specific simulations are presented. This book is addressed to all scientists interested in the mathematical modeling and numerical simulation of the human cardiocirculatory system.

Simple, humorous text and comic illustrations explain the basics of the circulatory system--the systemic, pulmonary, and coronary circuits. Readers follow a red blood cell on its journey through the body, and in the process learn how the body combats disease, performs gas exchanges, and fights plaque.

The circulatory system doesn't just move blood around the body. It moves nutrients, oxygen, hormones, and electrolytes to exactly where they need to go, from the brain to the feet. Every body system relies on the network of veins, arteries, and capillaries throughout the body. While important, the circulatory system is also incredible interesting! Readers learn the basics of blood cells and blood vessels in fun, surprising, and even gross facts on each page. Diagrams and full-color photographs aid readers' understanding and provide a close encounter with parts of the body they may never see.