The first 1,000 days, from conception to two years of age, is a critical period of growth and development. Exposures to dietary, environmental, hormonal, and other stressors during this window have been associated with an increased risk of poor health outcomes, some of which are irreversible. The book addresses this crucial interval of early life across biological disciplines, linking concepts related to all biological fields to outcomes during the first 1,000 days (e.g. fetal growth and pregnancy outcomes) and beyond (e.g. gut microbiome and cardiovascular disease later in life). The strength of this book lies in its cross-disciplinary nature.

"Your child can achieve great things." A few years ago, pregnant women in four corners of the world heard those words and hoped they could be true. Among them were Esther Okwir in rural Uganda, where the infant mortality rate is among the highest in the world; Jessica Saldana, a high school student in a violence-scarred Chicago neighborhood; Shyamkali, the mother of four girls in a low-caste village in India; and Maria Estella, in Guatemala's western highlands, where most people are riddled with parasites and moms can rarely afford the fresh vegetables they farm. Greatness? It was an audacious thought, given their circumstances. But they had new cause to be hopeful: they were participating in an unprecedented international initiative designed to transform their lives, the lives of their children, and ultimately the world. The 1,000 Days movement, a response to recent, devastating food crises and new research on the economic and social costs of childhood hunger and stunting, is focused on providing proper nutrition during the first 1,000 days of children's lives, beginning with their mother's pregnancy. Proper nutrition during these days can profoundly influence an individual's ability to grow, learn, and work-and determine a society's long-term health and prosperity. In this inspiring, sometimes heartbreaking book, Roger Thurow takes us into the lives of families on the forefront of the movement to illuminate the science, economics, and politics of malnutrition, charting the exciting progress of this global effort and the formidable challenges it still faces: economic injustice, disease, lack of education and sanitation, misogyny, and corruption.

How to prevent and manage low birth weight Growth and nutrition during the fetal period and the first 24 months after birth are important determinants of development in early childhood. Optimal nutrition and health care of both the mother and infant during these first 1000 days of an infant's life are closely linked to growth, learning potential and neurodevelopment, in turn affecting long-term outcomes. Children with low birth weight do not only include premature babies, but also those with intrauterine growth restrictions who consequently have a very high risk of developing metabolic syndrome in the future. Epidemiology, epigenetic programming, the correct nutrition strategy and monitoring of outcomes are thus looked at carefully in this book. More specifically, two important nutritional issues are dealt with in depth: The first being the prevention of low birth weight, starting with the health of adolescent girls, through the pre-pregnancy and pregnancy stages and ending with lactation. The second point of focus concerns the nutritional follow-up and feeding opportunities in relation to dietary requirements of children with low birth weight.

The first 1,000 days, from conception to two years of age, is a critical period of growth and development. Exposures to dietary, environmental, hormonal, and other stressors during this window have been associated with an increased risk of poor health outcomes, some of which are irreversible. The book addresses this crucial interval of early life across biological disciplines, linking concepts related to all biological fields to outcomes during the first 1,000 days (e.g. fetal growth and pregnancy outcomes) and beyond (e.g. gut microbiome and cardiovascular disease later in life). The strength of this book lies in its cross-disciplinary nature.

"Your child can achieve great things." A few years ago, pregnant women in four corners of the world heard those words and hoped they could be true. Among them were Esther Okwir in rural Uganda, where the infant mortality rate is among the highest in the world; Jessica Saldana, a high school student in a violence-scarred Chicago neighborhood; Shyamkali, the mother of four girls in a low-caste village in India; and Maria Estella, in Guatemala's western highlands, where most people are riddled with parasites and moms can rarely afford the fresh vegetables they farm. Greatness' It was an audacious thought, given their circumstances. But they had new cause to be hopeful: they were participating in an unprecedented international initiative designed to transform their lives, the lives of their children, and ultimately the world. The 1,000 Days movement, a response to recent, devastating food crises and new research on the economic and social costs of childhood hunger and stunting, is focused on providing proper nutrition during the first 1,000 days of children's lives, beginning with their mother's pregnancy. Proper nutrition during these days can profoundly influence an individual's ability to grow, learn, and work-and determine a society's long-term health and prosperity. In this inspiring, sometimes heartbreaking book, Roger Thurow takes us into the lives of families on the forefront of the movement to illuminate the science, economics, and politics of malnutrition, charting the exciting progress of this global effort and the formidable challenges it still faces: economic injustice, disease, lack of education and sanitation, misogyny, and corruption.

The first 1,000 days, from conception to 2 years of age, is a critical window of growth and development. Exposures to dietary, environmental, hormonal, and other stressors during this period have been associated with an increased risk of adverse health outcomes. Researchers using cell culture, animal models, and humans have identified this time as a period of rapid physiological change and plasticity with significant potential for lasting effects. As such, interventions during the first 1,000 days will have the greatest impact on outcomes, particularly in low- and middle-income countries where the need is greatest. To date, there is no single resource that compiles our knowledge of the biology of the first 1,000 days. Our knowledge and understanding of the biology behind the first 1,000 days is still limited. This greater understanding is helping us inform effective nutrition policy and programming. The strength of this book lies in its cross- disciplinary nature that encompasses the full range of human biology, providing a more holistic perspective during this critical time frame. Moreover, we have broadened the scope and included important periods before and after the 1,000 days. We have designed this book as a comprehensive resource for those involved in global health and nutrition policy, strategy, programming, or research. This book will also be a resource for students learning about nutrition and health across the 1,000 days. The book includes an exceptional group of contributors who are experts in their given fields. As biology underlies the core of each discussion, it allows the readers to answer the what and why, and, we hope, the how for new discovery research and more effective interventions. Each chapter in this volume provides insight into a specific life stage, disease state, nutrient, and stressor in the first 1,000 days. As such, each chapter can be read independently, providing a comprehensive overview of that subject. However, there is continuity between chapters allowing this collection of chapters to be read cover to cover. The first chapters set the stage, providing a succinct resource to understand the well-established biological mechanisms that underlie growth regulation and nutrient recommendations throughout the first 1,000 days. The next chapters move on to the evidence behind nutrition-specific and nutrition-sensitive interventions to combat adverse outcomes and disease states in the first 1,000 days. This book also features emerging research areas, such as the gut microbiome, environmental enteric dysfunction, and the role of epigenetics in health and development. The final chapter pushes the boundaries of discovery research, exploring novel areas such as proteomics and metabolomics, and how insults such as environmental enteric dysfunction affect metabolism in the first 1,000 days. We approached this book with the ambition to shed more light on the biology during 1,000 days, but there was also a need to put the biology into a broader context of nutrition and health. There are still many gaps in our understanding of the biology of the first 1,000 days. It is only by bridging this knowledge gap through research that we can inform effective interventions to improve outcomes during the first 1,000 days.

This book provides a philosophical, socio-political and theoretical understanding of the notion of Becoming in the context of the related concepts, and in contemplation of the notion of Being. Deriving from different traditions from various countries, these concepts act as windows on contemporary early years settings and communities around the world where adults map out infant becomings. This book is a valuable resource for early childhood educators, students, professionals, researchers, and policy makers around the globe who seek to understand the locatedness of infant becomings in space and time.