Accurate clinical observations are key to good patient care and fundamental to clinical practice. A thorough understanding of the biological science underlying vital observations – such as taking the temperature or measuring the pulse – enables health professionals to make well-informed clinical decisions quickly and accurately. To be fully competent in these basic skills, there is a need to understand not only how and why procedures are performed, but also how results are affected, for example by variation in technique or the health status of the patient. This new edition integrates clear explanations of the techniques involved in these procedures with the biological knowledge which gives them meaning. For each topic, William T. Blows explains the pathological basis for variations in observed results, focusing on relevant anatomy and physiology, genetics and pharmacology and the basic principles of care. This helpful text gives health practitioners at all levels the understanding needed to: Perform clinical observations accurately Make accurate judgements about the patient’s condition Make accurate decisions concerning patient care. In addition to all-new chapters on observations of nutrition; fluid balance and hydration; drug side effects and interactions; skin and pain, the text looks at: Temperature Cardiovascular observations Respiratory observations Urinary and bowel observations Neurological observations The Biological Basis of Clinical Observations is a unique text which integrates explanations of essential procedures with the biological knowledge that underpins practice. It is essential reading for all students preparing for clinical practice.

Accurate clinical observations are fundamental to competent and safe healthcare practice. The Biological Basis of Clinical Observations gives readers the understanding needed to perform clinical observations accurately, make accurate judgements about the patient’s condition and make accurate decisions concerning patient care. This useful textbook integrates clear explanations of the techniques involved in making clinical observations, alongside the biological knowledge which gives them meaning. For each topic, it explains the pathological basis for variations in observed results, focusing on relevant anatomy and physiology, genetics and pharmacology, and the basic principles of care. In addition to new chapters on blood tests and pregnancy, the text has been updated throughout. It now incorporates increased coverage of paediatrics, movement and the musculo-skeletal system, the lymphatic system, pregnancy, diabetes, homeostasis and infection, among other areas. Topics discussed include: temperature cardiovascular observations respiratory observations urinary and bowel observations neurological observations nutrition fluid balance skin drug side effects, interactions and allergies. The Biological Basis of Clinical Observations is a unique text which integrates explanations of essential procedures with the biological knowledge that underpins practice. It is essential reading for all nursing and health students preparing for clinical practice.

Accurate clinical observations are the key to good patient care and fundamental to nursing practice. To be fully competent in these basic skills, nurses need to understand not only how and why procedures are performed, but also how results are affected for example by variation in technique or the health status of the patient. The Biological Basis of Nursing: Clinical Observation is a unique text which integrates explanations of essential nursing procedures with the biological knowledge that underpins practice. Essential reading for all students preparing for clinical practice in nursing.

Newly developed molecular target anticancer drugs have shown remarkable efficacy even in the treatment of intractable cancers such as hepatoma and renal cell carcinoma. As cancer research is becoming a multidisciplinary endeavor, close cooperation across the basic, translational, and clinical research fields holds the promise of further advances in cancer therapeutics. This book sets forth new strategies for development: cancer therapy targeting receptor tyrosine kinases with clinical utilization of new signaling regulations; interaction between cancer progression and extracellular environments such as inflammatory cytokines and the extracellular matrix; and investigation of biomarkers for personalized cancer therapy, with microarray analysis and pharmacogenomics technology. These and other findings from the latest investigations into cancer cell biology and therapeutics make this book an invaluable source for investigators in both the clinical and basic cancer research fields.

Written by an experienced nurse lecturer who also trained as a mental health nurse, this book explores the underlying biology associated with the pathology of mental health disorders and the related nervous system. Fully revised for this second edition, the text includes three new chapters on brain development,pharmacology and learning, behavioural and developmental disorders. Integrating up-to-date pharmacological and genetic knowledge with an understanding of environmental factors that impact on human biology, The Biological Basis of Mental Health Nursing covers topics including: the physiology of neurotransmission and receptors hormones and mental health the biology of emotions, stress, anxiety and phobic states the biology of substance abuse the pharmacology of psychoactive drugs developmental disorders brain anatomy and development the biology of behaviour genetics and mental health affective disorders: depression, mania and suicide schizophrenia autism and other syndromes the ageing brain and dementia degenerative diseases of the brain epilepsy. Accessibly laid out, with many of diagrams, tables and key points at the end of each chapter, this is an essential text for mental health nursing students, practitioners and educators.

This book explores the underlying biology associated with the pathology of mental health disorders and the related nervous system. Fully revised for this third edition, each chapter has been updated to include the latest research, ideas and concepts in each field, and includes a new chapter on sleep. Integrating up-to-date pharmacological and genetic knowledge with an understanding of environmental factors that impact on human biology, The Biological Basis of Mental Health covers topics including brain development, neural communication, neurotransmitters and receptors, hormones and behaviour, genetic disorders, pharmacology, drug abuse, anxiety, schizophrenia, depression, epilepsy, subcortical degenerative diseases of the brain, dementia, developmental disorders, and sleep. Accessible and engaging, this is an essential text for mental health students, practitioners and educators.

Written by an experienced nurse lecturer who also trained as a mental health nurse, this book explores the underlying biology associated with the pathology of mental health disorders and the related nervous system. Integrating related pharmacological and genetic knowledge, The Biological Basis of Nursing: Mental Health covers topics including: the physiology of neurotransmission and receptors the normal human brain hormones and mental health the biology of emotions, stress, anxiety and phobic states the biology of substance abuse developmental disorders genetics and mental health affective disorders: depression and suicide schizophrenia the ageing brain and dementia degenerative diseases of the brain epilepsy and sleep disorders. Relevant to nurses at all stages of their training, this is an essential text for mental health nursing students, practitioners and educators.