The Application of Functional Metagenomics to Natural Products Research

The Application of Functional Metagenomics to Natural Products Research
Title The Application of Functional Metagenomics to Natural Products Research PDF eBook
Author Jeffrey William Craig
Publisher
Pages 390
Release 2012
Genre
ISBN

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Functional Metagenomics: Tools and Applications

Functional Metagenomics: Tools and Applications
Title Functional Metagenomics: Tools and Applications PDF eBook
Author Trevor C. Charles
Publisher Springer
Pages 256
Release 2017-10-09
Genre Science
ISBN 3319615106

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In this book, the latest tools available for functional metagenomics research are described.This research enables scientists to directly access the genomes from diverse microbial genomes at one time and study these “metagenomes”. Using the modern tools of genome sequencing and cloning, researchers have now been able to harness this astounding metagenomic diversity to understand and exploit the diverse functions of microorganisms. Leading scientists from around the world demonstrate how these approaches have been applied in many different settings, including aquatic and terrestrial habitats, microbiomes, and many more environments. This is a highly informative and carefully presented book, providing microbiologists with a summary of the latest functional metagenomics literature on all specific habitats.

The New Science of Metagenomics

The New Science of Metagenomics
Title The New Science of Metagenomics PDF eBook
Author National Research Council
Publisher National Academies Press
Pages 170
Release 2007-06-24
Genre Science
ISBN 0309106761

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Although we can't usually see them, microbes are essential for every part of human life-indeed all life on Earth. The emerging field of metagenomics offers a new way of exploring the microbial world that will transform modern microbiology and lead to practical applications in medicine, agriculture, alternative energy, environmental remediation, and many others areas. Metagenomics allows researchers to look at the genomes of all of the microbes in an environment at once, providing a "meta" view of the whole microbial community and the complex interactions within it. It's a quantum leap beyond traditional research techniques that rely on studying-one at a time-the few microbes that can be grown in the laboratory. At the request of the National Science Foundation, five Institutes of the National Institutes of Health, and the Department of Energy, the National Research Council organized a committee to address the current state of metagenomics and identify obstacles current researchers are facing in order to determine how to best support the field and encourage its success. The New Science of Metagenomics recommends the establishment of a "Global Metagenomics Initiative" comprising a small number of large-scale metagenomics projects as well as many medium- and small-scale projects to advance the technology and develop the standard practices needed to advance the field. The report also addresses database needs, methodological challenges, and the importance of interdisciplinary collaboration in supporting this new field.

Improvements in Natural Product Biosynthetic Gene Clusters Research and Functional Trait-based Approaches in Metagenomics

Improvements in Natural Product Biosynthetic Gene Clusters Research and Functional Trait-based Approaches in Metagenomics
Title Improvements in Natural Product Biosynthetic Gene Clusters Research and Functional Trait-based Approaches in Metagenomics PDF eBook
Author Emiliano Pereira
Publisher
Pages
Release 2020
Genre Metagenomics
ISBN

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From Genes to Species: Novel Insights from Metagenomics

From Genes to Species: Novel Insights from Metagenomics
Title From Genes to Species: Novel Insights from Metagenomics PDF eBook
Author Eamonn P. Culligan
Publisher Frontiers Media SA
Pages 231
Release 2016-10-07
Genre Microbiology
ISBN 2889199754

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The majority of microbes in many environments are considered “as yet uncultured” and were traditionally considered inaccessible for study through the microbiological gold standard of pure culture. The emergence of metagenomic approaches has allowed researchers to access and study these microbes in a culture-independent manner through DNA sequencing and functional expression of metagenomic DNA in a heterologous host. Metagenomics has revealed an extraordinary degree of diversity and novelty, not only among microbial communities themselves, but also within the genomes of these microbes. This Research Topic aims to showcase the utility of metagenomics to gain insights on the microbial and genomic diversity in different environments by revealing the breadth of novelty that was in the past, largely untapped.

Using Genomics, Metagenomics and Other "Omics" to Assess Valuable Microbial Ecosystem Services and Novel Biotechnological Applications

Using Genomics, Metagenomics and Other
Title Using Genomics, Metagenomics and Other "Omics" to Assess Valuable Microbial Ecosystem Services and Novel Biotechnological Applications PDF eBook
Author Diana Elizabeth Marco
Publisher Frontiers Media SA
Pages 674
Release 2019-05-15
Genre
ISBN 2889458148

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Most ecosystem services and goods human populations use and consume are provided by microbial populations and communities. Indeed, numerous provisioning services (e.g. food and enzymes for industrial processes), regulating services (e.g. water quality, contamination alleviation and biological processes such as plant-microbial symbioses), and supporting services (e.g. nutrient cycling, agricultural production and biodiversity) are mediated by microbes. The fast development of metagenomics and other meta-omics technologies is expanding our understanding of microbial diversity, ecology, evolution and functioning. This enhanced knowledge directly translates into the emergence of new applications in an unlimited variety of areas across all microbial ecosystem services and goods. The varied topics addressed in this Research Topic include the development of innovative industrial processes, the discovery of novel natural products, the advancement of new agricultural methods, the amelioration of negative effects of productive or natural microbiological processes, as well as food security and human health, and archeological conservation. The articles compiled provide an updated, high-quality overview of current work in the field. This body of research makes a valuable contribution to the understanding of microbial ecosystem services, and expands the horizon for finding and developing new and more efficient biotechnological applications.

Metagenomics and Microbial Ecology

Metagenomics and Microbial Ecology
Title Metagenomics and Microbial Ecology PDF eBook
Author Surajit De Mandal
Publisher CRC Press
Pages 266
Release 2021-11-29
Genre Nature
ISBN 1000482235

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Microorganisms comprise the greatest genetic diversity in the natural ecosystem, and characterization of these microbes is an essential step towards discovering novel products or understanding complex biological mechanisms. The advancement of metagenomics coupled with the introduction of high-throughput, cost-effective NGS technology has expanded the possibilities of microbial research in various biological systems. In addition to traditional culture and biochemical characteristics, omics approaches (metagenomics, metaproteomics, and metatranscriptomics) are useful for analyzing complete microbial communities and their functional attributes in various environments. Metagenomics and Microbial Ecology: Techniques and Applications explores the most recent advances in metagenomics research in the landscape of next-generation sequencing technologies. This book also describes how advances in sequencing technologies are used to study invisible microbes as well as the relationships between microorganisms in their respective environments. Features: Covers a wide range of concepts, investigations, and technological advancement in metagenomics at the global level. Highlights the novel and recent approaches to analyze microbial diversity and its functional attributes. Features a range of chapters that present an introduction to the field and functional insight into various ecosystems.