Explores the history of vaccine development and the rise of antivaccination societies in late-nineteenth-century America.

Vaccines save millions of lives every year, and one man, Maurice Hilleman, was responsible for nine of the big fourteen. Paul Offit recounts his story and the story of vaccines Maurice Hilleman discovered nine vaccines that practically every child gets, rendering formerly dread diseases—including often devastating ones such as mumps and rubella—practically forgotten. Paul A. Offit, a vaccine researcher himself, befriended Hilleman and, during the great man’s last months, interviewed him extensively about his life and career. Offit makes an eloquent and compelling case for Hilleman’s importance, arguing that, like Jonas Salk, his name should be known to everyone. But Vaccinated is also enriched and enlivened by a look at vaccines in the context of modern medical science and history, ranging across the globe and throughout time to take in a fascinating cast of hundreds, providing a vital contribution to the continuing debate over the value of vaccines.

There is considerable interest now in the contemporary lives of the so-called traditional medicines of South Asia and beyond. "Doctoring Traditions, "which examines Ayurveda in British India, particularly Bengal, roughly from the 1860s to the 1930s, is a welcome departure even within the available work in the area. For in it the author subtly interrogates the therapeutic changes that created modern Ayurveda. He does so by exploring how Ayurvedic ideas about the body changed dramatically in the modern period and by breaking with the oft-repeated but scantily examined belief that changes in Ayurvedic understandings of the body were due to the introduction of cadaveric dissections and Western anatomical knowledge. "Doctoring Traditions" argues that the actual motor of change were a number of small technologies that were absorbed into Ayurvedic practice at the time, including thermometers and microscopes. In each of its five core chapters the book details how the adoption of a small technology set in motion a dramatic refiguration of the body. This book will be required reading for historians both of medicine and South Asia.

Today, when many parents seem reluctant to have their children vaccinated, even with long proven medications, the Salk vaccine trial, which enrolled millions of healthy children to test an unproven medical intervention, seems nothing short of astonishing. In Selling Science, medical historian Stephen E. Mawdsley recounts the untold story of the first large clinical trial to control polio using healthy children—55,000 healthy children—revealing how this long-forgotten incident cleared the path for Salk’s later trial. Mawdsley describes how, in the early 1950s, Dr. William Hammon and the National Foundation for Infantile Paralysis launched a pioneering medical experiment on a previously untried scale. Conducted on over 55,000 healthy children in Texas, Utah, Iowa, and Nebraska, this landmark study assessed the safety and effectiveness of a blood component, gamma globulin, to prevent paralytic polio. The value of the proposed experiment was questioned by many prominent health professionals as it harbored potential health risks, but as Mawdsley points out, compromise and coercion moved it forward. And though the trial returned dubious results, it was presented to the public as a triumph and used to justify a federally sanctioned mass immunization study on thousands of families between 1953 and 1954. Indeed, the concept, conduct, and outcome of the GG study were sold to health professionals, medical researchers, and the public at each stage. At a time when most Americans trusted scientists, their mutual encounter under the auspices of conquering disease was shaped by politics, marketing, and at times, deception. Drawing on oral history interviews, medical journals, newspapers, meeting minutes, and private institutional records, Selling Science sheds light on the ethics of scientific conduct, and on the power of marketing to shape public opinion about medical experimentation.

A “clear and insightful” takedown of the anti-vaccination movement, from its 19th-century antecedents to modern-day Facebook activists—with strategies for refuting false claims of friends and family (Financial Times) Vaccines are a documented success story, one of the most successful public health interventions in history. Yet there is a vocal anti-vaccination movement, featuring celebrity activists (including Kennedy scion Robert F. Kennedy Jr. and actress Jenny McCarthy) and the propagation of anti-vax claims through books, documentaries, and social media. In Anti-Vaxxers, Jonathan Berman explores the phenomenon of the anti-vaccination movement, recounting its history from its nineteenth-century antecedents to today’s activism, examining its claims, and suggesting a strategy for countering them. After providing background information on vaccines and how they work, Berman describes resistance to Britain’s Vaccination Act of 1853, showing that the arguments anticipate those made by today’s anti-vaxxers. He discusses the development of new vaccines in the twentieth century, including those protecting against polio and MMR (measles, mumps, rubella), and the debunked paper that linked the MMR vaccine to autism; the CDC conspiracy theory promoted in the documentary Vaxxed; recommendations for an alternative vaccination schedule; Kennedy’s misinformed campaign against thimerosal; and the much-abused religious exemption to vaccination. Anti-vaxxers have changed their minds, but rarely because someone has given them a list of facts. Berman argues that anti-vaccination activism is tied closely to how people see themselves as parents and community members. Effective pro-vaccination efforts should emphasize these cultural aspects rather than battling social media posts.

An “intriguing and accessible” (Publishers Weekly) interpretation of the life of Galileo Galilei, one of history’s greatest and most fascinating scientists, that sheds new light on his discoveries and how he was challenged by science deniers. “We really need this story now, because we’re living through the next chapter of science denial” (Bill McKibben). Galileo’s story may be more relevant today than ever before. At present, we face enormous crises—such as minimizing the dangers of climate change—because the science behind these threats is erroneously questioned or ignored. Galileo encountered this problem 400 years ago. His discoveries, based on careful observations and ingenious experiments, contradicted conventional wisdom and the teachings of the church at the time. Consequently, in a blatant assault on freedom of thought, his books were forbidden by church authorities. Astrophysicist and bestselling author Mario Livio draws on his own scientific expertise and uses his “gifts as a great storyteller” (The Washington Post) to provide a “refreshing perspective” (Booklist) into how Galileo reached his bold new conclusions about the cosmos and the laws of nature. A freethinker who followed the evidence wherever it led him, Galileo was one of the most significant figures behind the scientific revolution. He believed that every educated person should know science as well as literature, and insisted on reaching the widest audience possible, publishing his books in Italian rather than Latin. Galileo was put on trial with his life in the balance for refusing to renounce his scientific convictions. He remains a hero and inspiration to scientists and all of those who respect science—which, as Livio reminds us in this “admirably clear and concise” (The Times, London) book, remains threatened everyday.

From the Pulitzer Prize–winning author of The Looming Tower, and the pandemic novel The End of October: an unprecedented, momentous account of Covid-19—its origins, its wide-ranging repercussions, and the ongoing global fight to contain it "A book of panoramic breadth ... managing to surprise us about even those episodes we … thought we knew well … [With] lively exchanges about spike proteins and nonpharmaceutical interventions and disease waves, Wright’s storytelling dexterity makes all this come alive.” —The New York Times Book Review From the fateful first moments of the outbreak in China to the storming of the U.S. Capitol to the extraordinary vaccine rollout, Lawrence Wright’s The Plague Year tells the story of Covid-19 in authoritative, galvanizing detail and with the full drama of events on both a global and intimate scale, illuminating the medical, economic, political, and social ramifications of the pandemic. Wright takes us inside the CDC, where a first round of faulty test kits lost America precious time . . . inside the halls of the White House, where Deputy National Security Adviser Matthew Pottinger’s early alarm about the virus was met with confounding and drastically costly skepticism . . . into a Covid ward in a Charlottesville hospital, with an idealistic young woman doctor from the town of Little Africa, South Carolina . . . into the precincts of prediction specialists at Goldman Sachs . . . into Broadway’s darkened theaters and Austin’s struggling music venues . . . inside the human body, diving deep into the science of how the virus and vaccines function—with an eye-opening detour into the history of vaccination and of the modern anti-vaccination movement. And in this full accounting, Wright makes clear that the medical professionals around the country who’ve risked their lives to fight the virus reveal and embody an America in all its vulnerability, courage, and potential. In turns steely-eyed, sympathetic, infuriated, unexpectedly comical, and always precise, Lawrence Wright is a formidable guide, slicing through the dense fog of misinformation to give us a 360-degree portrait of the catastrophe we thought we knew.