Self-help books don't seem to work. Few of the many advantages of modern life seem capable of lifting our collective mood. Wealth—even if you can get it—doesn't necessarily lead to happiness. Romance, family life, and work often bring as much stress as joy. We can't even agree on what "happiness" means. So are we engaged in a futile pursuit? Or are we just going about it the wrong way? Looking both east and west, in bulletins from the past and from far afield, Oliver Burkeman introduces us to an unusual group of people who share a single, surprising way of thinking about life. Whether experimental psychologists, terrorism experts, Buddhists, hardheaded business consultants, Greek philosophers, or modern-day gurus, they argue that in our personal lives, and in society at large, it's our constant effort to be happy that is making us miserable. And that there is an alternative path to happiness and success that involves embracing failure, pessimism, insecurity, and uncertainty—the very things we spend our lives trying to avoid. Thought-provoking, counterintuitive, and ultimately uplifting, The Antidote is the intelligent person's guide to understanding the much-misunderstood idea of happiness.

From the author of The Freemason’s Daughter comes a lush romantic fantasy perfect for fans of Everless! In the world of healers, there is no room for magic. Fee knows this, just as certainly as she knows that her magic must be kept secret. But the crown prince Xavi, Fee’s best friend and only source of comfort, is sick. So sick, that Fee can barely contain the magic lying dormant inside her. She could use it, just a little, to heal him. But magic comes at a deadly cost—and attracts those who would seek to snuff it out forever. A wisp of a spell later, Fee finds herself caught in a whirl of secret motivations and dark pasts, where no one is who—or what—they appear to be. And saving her best friend means delving deeper into the tempting and treacherous world whose call she’s long resisted—uncovering a secret that will change everything. Laini Taylor meets Sara Holland in this lavish fantasy from lauded historical romance author Shelley Sackier!

In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Journalist Barry Werth described the company's tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell the story of Vertex's bold endurance and eventual success. The pharmaceutical business is America's toughest and one of its most profitable. It's riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine; to the multibillion-dollar cost of ramping up a successful product; to operating in the world's most regulated industry, matched only by nuclear power. Werth captures the full scope of Vertex's 25-year drive to deliver breakthrough medicines.--From publisher description.

In this whip-smart and timely novel from acclaimed author Kimmery Martin, two doctors travel a surprising path when they must choose between treating their patients and keeping their jobs. Georgia Brown’s profession as a urologist requires her to interact with plenty of naked men, but her romantic prospects have fizzled. The most important person in her life is her friend Jonah Tsukada, a funny, empathetic family medicine doctor who works at the same hospital in Charleston, South Carolina and who has become as close as family to her. Just after Georgia leaves the country for a medical conference, Jonah shares startling news. The hospital is instructing doctors to stop providing medical care for transgender patients. Jonah, a gay man, is the first to be fired when he refuses to abandon his patients. Stunned by the predicament of her closest friend, Georgia’s natural instinct is to fight alongside him. But when her attempts to address the situation result in incalculable harm, both Georgia and Jonah find themselves facing the loss of much more than their careers.

Twelve-year-old Alex Revelstoke is different. He can see disease. Also injury, illness, and anything else wrong with the body. This comes in handy when a classmate chokes on a hot dog or when the janitor suffers a heart attack unclogging a gooey science experiment gone awry. But Alex soon learns his new ability puts him and an unsuspecting world in peril. Throughout time, Revelstokes have waged a battle against ancient evil itself. A man, a being, an essence—the creator of disease. Alex has seen its darkness. He has felt its strength. He does not want to fight. But Alex is the last Revelstoke. The war has just begun.

Readers were instantly beguiled by Rob Brezsny's new approach to the humble horoscope when his "Free Will Astrology" column first appeared in 1996. Instead of the generic, one-size-fits-all style of similar columns, Brezsny used witty parables, tender rants, cultural riffs, pagan wisdom, and lively rituals in his playfully positive readings. He brings that same sensibility—and the same message of a smiling universe—to this self-help book for people who may be skeptical about self-help books. Brezsny persuasively advises readers to go along with the universe's good intentions, but his rejection of cynicism and a bleak view of human nature isn't rooted in denial. On the contrary, he makes a case for a cagey optimism that requires a vigorous engagement with the dark forces. He asks us to rethink life as a sublime game created for our amusement and illumination. The book is a chameleon of a tome. You can read it straight through, slowly and surely, or else pick it up and open it at random for tasty hits of inspiration as the spirit moves you. You can even start at the end and weave your way backward. Brezsny has substantially updated this edition—he added nearly one hundred pages—by expanding various sections, adding more than a dozen new pieces and a new chapter, and providing readers with a number of playtime activities and exercises that let them participate through their own writing and drawing. "Brezsny's horoscopes are like little valentines, buoyant and spilling over with mischievousness. They're a soul prognosis." —The New York Times

"In this important book, Edy Greenblatt shows us the way to achieve a higher quality of life and how to eliminate so many of the stressors that plague and tire us - especially the self imposed ones." -Bronwyn Fryer, Senior Editor, Harvard Business Review "This inspiring book translates years of thoughtful social scientific research into actionable strategies for bringing positive energy back into our work and lives. Restore Yourself not only advances the argument that restoration is critical to both productivity and happiness, it shows us HOW to find that energy and then capitalize on it every day." -Monica C. Higgins, Associate Professor, Harvard Graduate School of Education, and author, Career Imprints: Creating Leaders Across an Industry .."astonishingly timely, useful and important. Please read it before you die because it may add a few years to your life." -Warren Bennis, Distinguished Professor of Business, University of Southern California and best selling author of Leaders, An Invented Life and On Becoming a Leader.