Issac Johnson (b. ca. 1722) was in the Shenahdoah Valley of Virginia about 1745, and claimed land there in 1749. Descendants lived throughout the United States.

Sanford Gladden traces the history of the Durst/Darst family and some 40 other related families from their European roots to Philadelphia in Colonial times. They migrated to the Shenandoah Valley of Virginia, to Delaware and Pickaway Counties in OH and on to Texas. Some of the related surnames are: Beck, Cecil, Chandler, Charlton, Cozad, Craig, Damon, Deam, Dill, Eaton, Ewing, Fry, Glendy, Glotfelter, Grigsby, Guy, Harshman, Haynes, Holman, Huston, Jamison, Keithly, Kennedy, Kent, Lightner, Marshall, Morgan, Orman, page, Perrins, Ramsey, Selling, Stroop, Trolinger, and Weiser among other smaller branches.