Textbook of Pulmonary Vascular Diseases combines basic scientific knowledge on the pulmonary circulatory system at levels of the molecule, cell, tissue, and organ with clinical diagnosis and treatment of pulmonary vascular diseases. State-of-the-art techniques and their potential applications in research, diagnosis, and treatment of pulmonary vascular diseases are also covered.

Offers a current and comprehensive review of the pathophysiology, diagnosis, and treatment of pulmonary hypertension and venous thromboembolism. Discusses indepth the pharmacologic and non-pharmacologic therapies used in the treatment of pulmonary vascular disease -- including the benefits and risks of each -- allowing for more informed care decisions.

This book provides the framework for a singular reference in the field of pulmonary hypertension. Pulmonary vascular disease is a complex and heterogeneous condition characterized by remodeling of distal pulmonary arterioles that increases pulmonary vascular resistance to affect cardiopulmonary hemodynamic and right ventricular function adversely, resulting in a clinical syndrome of diminished exercise tolerance, shortness of breath, and heart failure-associated morbidity and mortality. Owing to the availability of novel pulmonary circulation-selective pharmacotherapies over the previous decade, the number of pulmonary hypertension patients eligible for treatment has increased substantially. Despite this progress, under-awareness persists within the practicing pulmonary, cardiovascular, and general internal medicine communities. This is due, in part, to the complex array of molecular mechanisms implicated in the pathobiology of PH, as well as cutting-edge discoveries from translational scientific works that provide a new framework by which to understand pulmonary vascular-right ventricular coupling. Taken together, a key educational opportunity is exposed to bridge this knowledge gap through the synthesis of a contemporary text that emphasizes basic science, translational and clinical principles, and treatment strategies for understanding pulmonary hypertension.

Pulmonary Circulation provides physicians with a better understanding of the structure, function and pathophysiology of the pulmonary circulation. It provides comprehensive coverage from diagnosis and clinical evaluation of patients with pulmonary hypertension to imaging techniques, disorders and treatment. This new edition incorporates the latest clinical, pathophysiological and pathological research on pulmonary circulatory disorders. In particular, it provides greater emphasis on the role of the right ventricle in pulmonary vascular disease, updated knowledge on pathobiology and genetics, and includes new material related to imaging and other diagnostic modalities. This edition also reflects new classifications and all the recommendations from the 2013 World Conference on Pulmonary Circulation as well as current guidelines from the European Society of Cardiology and the European Respiratory Society. Thoroughly updated to keep up with the brisk pace of discovery and emerging therapies, the book remains an essential resource by providing a balance between scientific review and clinically relevant guidelines for the busy practicing physician.

This book is a clinical guide to controversial and emerging topics in pulmonary hypertension. There are multiple challenges and unanswered questions encountered by clinicians that evaluate, diagnose and treat patients with suspected or confirmed pulmonary vascular disease. This book provides a deep dive into the diagnosis and therapeutics of pulmonary hypertension supported by the literature and balanced with personal clinical experience. Expert authors have chosen these specific topics to address issues where uncertainty and/or controversy exists as well as highlight areas that are just being incorporated into clinical practice. These topics include: exercise pulmonary hypertension, sickle cell disease and pulmonary hypertension, and sarcoid pulmonary hypertension, among many others. Chapters address the diagnostic and treatment dilemmas posed by these various clinical entities through literature review, sharing of expert opinion, and review of recent guidelines and their applicability to the multiple different nuanced presentations of pulmonary hypertension. This is an ideal guide for pulmonologists, cardiologists, and other specialty practitioners caring for patients with pulmonary hypertension.

Authoritative, comprehensive and definitive, Pulmonary Circulation builds on the success of its previous two editions by providing practising respiratory physicians with a highly-ordered, unique reference work on the structure, function and pathophysiology of the pulmonary circulation. New for the third edition: Thoroughly revised with comprehensive coverage from diagnosis and clinical evaluation of pulmonary hypertension, to imaging techniques, disorders and treatment A new truly global team of expert editors, authors and key opinion leaders provide a wealth of detail on the latest developments and issues New chapters, such as: paediatrics, critical care, special environments including high altitude and underwater More quality chapters, authors, illustrations with thorough and thoughtful referencing make this book a contemporary essential reference text Pulmonary Circulation remains an essential resource for pulmonary hypertension specialists and should prove invaluable in all respiratory, cardiac and intensive care units.