This Test Guideline describes a screening method for the evaluation of potential anaerobic biodegradability of organic chemicals under specific conditions. Washed digested sludge, containing low (

This Test Guideline describes a method to assess the extent and kinetics of primary and ultimate biodegradation of organic chemicals whose route of entry into the environment begins with their discharge to wastewater. It consists of five simulation ...

The OECD Guidelines for the Testing of Chemicals is a collection of about 150 of the most relevant internationally agreed testing methods used by government, industry and independent laboratories to identify and characterise potential hazards of chemicals. They are a set of tools for professionals, used primarily in regulatory safety testing and subsequent chemical and chemical product notification, chemical registration and in chemical evaluation. They can also be used for the selection and ranking of candidate chemicals during the development of new chemicals and products and in toxicology research. This group of tests covers environmental fate and behaviour. In 2017, the section 3 "Degradation and Accumulation" was renamed to " Environmental fate and behaviour" to take into account Test Guidelines measuring endpoints such as dispersion, aggregation.

This Test Guideline describes a method, which can provide information that is useful in predicting the likely effect of a test substance on gas production in anaerobic digesters. Aliquots of a mixture of anaerobically digesting sludge (20 g/L to 40 ...

This book discusses bioavailability concepts and methods, summarizing the current knowledge on bioavailability science, as well as possible pathways for integrating bioavailability into risk assessment and the regulation of organic chemicals. Divided into 5 parts, it begins with an overview of chemical distribution in soil and sediment, as well as the bioavailability and bioaccumulation of chemicals in plants, soil, invertebrates and vertebrates (including humans). It then focuses on the impact of sorption processes and reviews bioavailability measurement methods. The closing chapters discuss the impact of bioavailability studies on chemical risk assessment, and highlights further research needs. Written by a multi-disciplinary team of authors, it is an essential resource for scientists in academia and industry, students, as well as for authorities.

Developed from the efforts of a multiyear, international project examining how persistent, bioaccumulative, and toxic (PBT) chemicals are evaluated and managed, Persistent, Bioaccumulative, and Toxic (PBT) Chemicals: Technical Aspects, Policies, and Practices focuses on improving the processes that govern PBTs. Incorporating science and policy literature—as well as interviews and panel discussions featuring experts from around the world—this book provides you with an international perspective of PBT policies (centering on Europe, Asia, and North America), and reveals major findings and recommendations for improving PBT science, laws, and policies. It includes case studies of specific chemicals, provides an introduction to the overall subject of toxic chemicals, and weighs in on science and policy expansion for PBTs. It also provides summary tables of important PBTs, and discussions on the number of PBTs in commerce, weight of evidence approaches, market deselection, and international management. The text: Assesses the history, current practice, and future of PBT management Considers the roles scientific data, modeling, and conventions play in identifying and regulating PBTs Explores the number of PBTs in commerce and the growing role of weight of evidence (WOE) in the making of PBT determinations Identifies issues that are likely to come up in WOE judgments Examines international, national, subnational, and regional PBT policies Includes a comprehensive and easy-to-understand analysis of PBT science and policy This book reviews the current science, policies, and practices surrounding the regulation of PBTs. It also provides relevant research, recommendations, and suggestions for improving the management and oversight of PBTs.

Understand the fundamentals of human risk assessment with this introduction and reference Human risk assessments are a precondition for virtually all industrial action or environmental regulation, all the more essential in a world where chemical and environmental hazards are becoming more abundant. These documents catalog potential environmental, toxicological, ecological, or other harms resulting from a particular hazard, from chemical spills to construction projects to dangerous workplaces. They turn on a number of variables, of which the most significant is the degree of human exposure to the hazardous agent or process. Human and Ecological Risk Assessment combines the virtues of a textbook and reference work to introduce and analyze these vital documents. Beginning with the foundational theory of human health risk assessment, it then supplies case studies and detailed analysis illustrating the practice of producing risk assessment documents. Fully updated and authored by leading authorities in the field, the result is an indispensable work. Readers of the second edition of Human and Ecological Risk Assessment will also find: Over 40 entirely new case studies reflecting the latest in risk assessment practice Detailed discussion of hazards including air emissions, contaminated food and soil, hazardous waste sites, and many more Case studies from multiple countries to reflect diverse international standards Human and Ecological Risk Assessment is ideal for professionals and advanced graduate students in toxicology, industrial hygiene, occupational medicine, environmental science, and all related subjects.