This book provides, for the first time, a detailed, up-to-date, holistic approach to the pathology and biology of germ cell tumors. The main focus is the complex histopathology of these tumors, but special considerations are also given to their morphologic variations in relation to age, gender and organ. Critical updates are provided on terminology and classification; the discussion of biology and pathogenesis includes references to many molecular genetic and immunohistochemical findings from recent stem cell research. Individual chapters are devoted to germ cell tumors at different anatomic locations, including not only the ovaries and testes but also the mediastinum and central nervous system, and pediatric tumors. All of the contributing authors are opinion leaders from universities of excellence in Europe and the United States. This monograph will be of wide interest to practitioners and researchers in many fields of medicine, including pathology, gynecology, urology, and pediatrics, as well as stem cell scientists.

This comprehensive and timely textbook covers all aspects of the evidence-based management of genitourinary cancers and explains the fundamental principles underlying the available diagnostic and treatment approaches, including chemotherapy, radiotherapy, immunotherapy, and surgery. For each type of cancer – prostate, bladder, renal, testicular, and penile, plus rare urologic malignancies – clinical presentation, diagnosis, and treatment strategies are described in detail and information is provided on etiology, epidemiology, risk factors, and pathology, including TNM classification. Careful attention is also devoted to the complications that may be encountered when treating urologic malignancies and to the management of these complications. The text is complemented by the inclusion of numerous high-definition photographs and illustrations. Urologic Oncology will be a valuable reference and source of guidance for all oncologists, urologists and practitioners in related disciplines who treat patients with urologic cancers.

World-class authorities provide a comprehensive and balanced evaluation of the advantages and disadvantages of screening for prostate cancer. These experts critically review the various methods by which screening can be performed, evaluate the screening itself, compare prostate screening with screening at other organ sites, and explore the impact of screening on a multitude of other medical and social issues. The book also includes a CD-ROM containing a sophisticated-but easy to use-decision-making program that allows the physician to gage a patient's risk of prostate cancer. Comprehensive and balanced, Prostate Cancer Screening, presents a lively and rigorous evaluation of the science of prostate cancer screening, affording the health care provider with an informative discussion of its pros and cons, together with a user-friendly computer program that analyzes an individual patient's risk of prostate cancer.

This book discusses how effective navigation requires a team approach to oncology care and should never be considered an “add-on” resource or service. The Academy of Oncology Nurse & Patient Navigators (AONN) is the only national professional organization for navigation professionals, and has more than 6,000 members, 90% of which are oncology nurse navigators. They are the experts on creating team-based programs, which remove the risk of others trying to reinvent the wheel by designing a navigation program from scratch. They also understand the role of effective navigation across the entire continuum of care, and understand and are able to apply other key aspects of navigation, including clinical trial screenings and tumor board coordination and monitoring, as well as measurement using evidence-based navigation metrics, to name but a few.It is the only book designed to educate and support anyone developing a new navigation program, or wanting to improve one they have created.As such it offers a guide for cancer centers needing to develop and implement an oncology navigation program; understand and successfully meet and exceed the Commission on Cancer accreditation standards linked to navigation; expand or improve their current navigation program as well as demonstrate its value using reliable measurable results, including patient satisfaction and improved- quality clinical outcomes. This comprehensive book also provides insights into applying the information presented to the real world of oncology care.

xxxxx proposes a radical, new space for artistic exploration, with essential contributions from a diverse range of artists, theorists, and scientists. Combining intense background material, code listings, screenshots, new translation, [the] xxxxx [reader] functions as both guide and manifesto for a thought movement which is radically opposed to entropic contemporary economies. xxxxx traces a clear line across eccentric and wide ranging texts under the rubric of life coding which can well be contrasted with the death drive of cynical economy with roots in rationalism and enlightenment thought. Such philosophy, world as machine, informs its own deadly flipside embedded within language and technology. xxxxx totally unpicks this hiroshimic engraving, offering an dandyish alternative by way of deep examination of software and substance. Life coding is primarily active, subsuming deprecated psychogeography in favour of acute wonderland technology, wary of any assumed transparency. Texts such as Endonomadology, a text from celebrated biochemist and chaos theory pioneer Otto E. Roessler, who features heavily throughout this intense volume, make plain the sadistic nature and active legacy of rationalist thought. At the same time, through the science of endophysics, a physics from the inside elaborated here, a delicate theory of the world as interface is proposed. xxxxx is very much concerned with the joyful elaboration of a new real; software-led propositions which are active and constructive in eviscerating contemporary economic culture. xxxxx embeds Perl Routines to Manipulate London, by way of software artist and Mongrel Graham Harwood, a Universal Dovetailer in the Lisp language from AI researcher Bruno Marchal rewriting the universe as code, and self explanatory Pornographic Coding from plagiarist and author Stewart Home and code art guru Florian Cramer. Software is treated as magical, electromystical, contrasting with the tedious GUI desktop applications and user-led drudgery expressed within a vast ghost-authored literature which merely serves to rehearse again and again the demands of industry and economy. Key texts, which well explain the magic and sheer art of programming for the absolute beginner are published here. Software subjugation is made plain within the very title of media theorist Friedrich Kittler's essay Protected Mode, published in this volume. Media, technology and destruction are further elaborated across this work in texts such as War.pl, Media and Drugs in Pynchon's Second World War, again from Kittler, and Simon Ford's elegant take on J.G Ballard's crashed cars exhibition of 1970, A Psychopathic Hymn. Software and its expansion stand in obvious relation to language. Attacking transparency means examining the prison cell or virus of language; life coding as William Burrough's cutup. And perhaps the most substantial and thorough-going examination is put forward by daring Vienna actionist Oswald Wiener in his Notes on the Concept of the Bio-adapter which has been thankfully unearthed here. Equally, Olga Goriunova's extensive examination of a new Russian literary trend, the online male literature of udaff.com provides both a reexamination of culture and language, and an example of the diversity of xxxxx; a diversity well reflected in background texts ranging across subjects such as Leibniz' monadology, the ur-crash of supreme flaneur Thomas de Quincey and several rewritings of the forensic model of Jack the Ripper thanks to Stewart Home and Martin Howse. xxxxx liberates software from the machinic, and questions the transparency of language, proposing a new world view, a sheer electromysticism which is well explained with reference to the works of Thomas Pynchon in Friedrich Kittler's essay, translated for the first time into English, which closes xxxxx. Further contributors include Hal Abelson, Leif Elggren, Jonathan Kemp, Aymeric Mansoux, and socialfiction.org.

Rose Colombo hit the news when she asked the question, "How much justice can you afford?" Colombo said she walked into the courtroom of no justice wealthy and walked out of the courtroom poor after she was thrust into the dark side of justice and felt as if she had been stripped of her freedom and thrown into a concentration camp with no rights. Most people know nothing about the legal system. We must not go down to their level but must force them to come up to our level.

This book discusses the impact on women of the diagnosis and treatment of early breast cancer. Readers will learn about the risks of breast cancer recurrence and interventions to reduce these, such as endocrine therapy and bisphosphonate therapy, as well as the role of lifestyle factors such as diet and exercise. The long-term effects of treatment on fertility, the heart and other systems are discussed, as well the psychological burden for women who are increasingly likely to be cured from their cancer. Each chapter provides background and a practical guide in the management of women after the initial phase of diagnosis and treatment. Authored by a multidisciplinary team this book provides all the relevant expertise as well as different perspectives, providing a holistic picture of early breast cancer consequences. From oncologists to general practitioners as well as specialist nurses, gynaecologists, psychologists and other healthcare professionals involved in the long-term care of women with breast cancer, this book provides a timely and indispensable guide to practitioners caring for early breast cancer survivors.