System theory is becoming increasingly important to medical applications. Yet, biomedical and digital signal processing researchers rarely have expertise in practical medical applications, and medical instrumentation designers usually are unfamiliar with system theory. System Theory and Practical Applications for Biomedical Signals bridges those gaps in a practical manner, showing how various aspects of system theory are put into practice by industry. The chapters are intentionally organized in groups of two chapters, with the first chapter describing a system theory technology, and the second chapter describing an industrial application of this technology. Each theory chapter contains a general overview of a system theory technology, which is intended as background material for the application chapter. Each application chapter contains a history of a highlighted medical instrument, summary of appropriate physiology, discussion of the problem of interest and previous empirical solutions, and review of a solution that utilizes the theory in the previous chapter. Biomedical and DSP academic researchers pursuing grants and industry funding will find its real-world approach extremely valuable. Its in-depth discussion of the theoretical issues will clarify for medical instrumentation managers how system theory can compensate for less-than-ideal sensors. With application MATLAB® exercises and suggestions for system theory course work included, the text also fills the need for detailed information for students or practicing engineers interested in instrument design. An Instructor Support FTP site is available from the Wiley editorial department: ftp://ftp.ieee.org/uploads/press/baura

Biomedical Signal Analysis Comprehensive resource covering recent developments, applications of current interest, and advanced techniques for biomedical signal analysis Biomedical Signal Analysis provides extensive insight into digital signal processing techniques for filtering, identification, characterization, classification, and analysis of biomedical signals with the aim of computer-aided diagnosis, taking a unique approach by presenting case studies encountered in the authors’ research work. Each chapter begins with the statement of a biomedical signal problem, followed by a selection of real-life case studies and illustrations with the associated signals. Signal processing, modeling, or analysis techniques are then presented, starting with relatively simple “textbook” methods, followed by more sophisticated research-informed approaches. Each chapter concludes with solutions to practical applications. Illustrations of real-life biomedical signals and their derivatives are included throughout. The third edition expands on essential background material and advanced topics without altering the underlying pedagogical approach and philosophy of the successful first and second editions. The book is enhanced by a large number of study questions and laboratory exercises as well as an online repository with solutions to problems and data files for laboratory work and projects. Biomedical Signal Analysis provides theoretical and practical information on: The origin and characteristics of several biomedical signals Analysis of concurrent, coupled, and correlated processes, with applications in monitoring of sleep apnea Filtering for removal of artifacts, random noise, structured noise, and physiological interference in signals generated by stationary, nonstationary, and cyclostationary processes Detection and characterization of events, covering methods for QRS detection, identification of heart sounds, and detection of the dicrotic notch Analysis of waveshape and waveform complexity Interpretation and analysis of biomedical signals in the frequency domain Mathematical, electrical, mechanical, and physiological modeling of biomedical signals and systems Sophisticated analysis of nonstationary, multicomponent, and multisource signals using wavelets, time-frequency representations, signal decomposition, and dictionary-learning methods Pattern classification and computer-aided diagnosis Biomedical Signal Analysis is an ideal learning resource for senior undergraduate and graduate engineering students. Introductory sections on signals, systems, and transforms make this book accessible to students in disciplines other than electrical engineering.

A comprehensive introduction to innovative methods in the field of biomedical signal analysis, covering both theory and practice. Biomedical signal analysis has become one of the most important visualization and interpretation methods in biology and medicine. Many new and powerful instruments for detecting, storing, transmitting, analyzing, and displaying images have been developed in recent years, allowing scientists and physicians to obtain quantitative measurements to support scientific hypotheses and medical diagnoses. This book offers an overview of a range of proven and new methods, discussing both theoretical and practical aspects of biomedical signal analysis and interpretation.After an introduction to the topic and a survey of several processing and imaging techniques, the book describes a broad range of methods, including continuous and discrete Fourier transforms, independent component analysis (ICA), dependent component analysis, neural networks, and fuzzy logic methods. The book then discusses applications of these theoretical tools to practical problems in everyday biosignal processing, considering such subjects as exploratory data analysis and low-frequency connectivity analysis in fMRI, MRI signal processing including lesion detection in breast MRI, dynamic cerebral contrast-enhanced perfusion MRI, skin lesion classification, and microscopic slice image processing and automatic labeling. Biomedical Signal Analysis can be used as a text or professional reference. Part I, on methods, forms a self-contained text, with exercises and other learning aids, for upper-level undergraduate or graduate-level students. Researchers or graduate students in systems biology, genomic signal processing, and computer-assisted radiology will find both parts I and II (on applications) a valuable handbook.

Covering the latest cutting-edge techniques in biomedical signal processing while presenting a coherent treatment of various signal processing methods and applications, this second edition of Practical Biomedical Signal Analysis Using MATLAB® also offers practical guidance on which procedures are appropriate for a given task and different types of data. It begins by describing signal analysis techniques—including the newest and most advanced methods in the field—in an easy and accessible way, illustrating them with Live Script demos. MATLAB® routines are listed when available, and freely available software is discussed where appropriate. The book concludes by exploring the applications of the methods to a broad range of biomedical signals while highlighting common problems encountered in practice. These chapters have been updated throughout and include new sections on multiple channel analysis and connectivity measures, phase-amplitude analysis, functional near-infrared spectroscopy, fMRI (BOLD) signals, wearable devices, multimodal signal analysis, and brain-computer interfaces. By providing a unified overview of the field, this book explains how to integrate signal processing techniques in biomedical applications properly and explores how to avoid misinterpretations and pitfalls. It helps readers to choose the appropriate method as well as design their own methods. It will be an excellent guide for graduate students studying biomedical engineering and practicing researchers in the field of biomedical signal analysis. Features: Fully updated throughout with new achievements, technologies, and methods and is supported with over 40 original MATLAB Live Scripts illustrating the discussed techniques, suitable for self-learning or as a supplement to college courses Provides a practical comparison of the advantages and disadvantages of different approaches in the context of various applications Applies the methods to a variety of signals, including electric, magnetic, acoustic, and optical Katarzyna J. Blinowska is a Professor emeritus at the University of Warsaw, Poland, where she was director of Graduate Studies in Biomedical Physics and head of the Department of Biomedical Physics. Currently, she is employed at the Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences. She has been at the forefront in developing new advanced time-series methods for research and clinical applications. Jarosław Żygierewicz is a Professor at the University of Warsaw, Poland. His research focuses on developing methods for analyzing EEG and MEG signals, brain-computer interfaces, and applications of machine learning in signal processing and classification.

Practical Biomedical Signal Analysis Using MATLAB® presents a coherent treatment of various signal processing methods and applications. The book not only covers the current techniques of biomedical signal processing, but it also offers guidance on which methods are appropriate for a given task and different types of data. The first several chapters of the text describe signal analysis techniques—including the newest and most advanced methods—in an easy and accessible way. MATLAB routines are listed when available and freely available software is discussed where appropriate. The final chapter explores the application of the methods to a broad range of biomedical signals, highlighting problems encountered in practice. A unified overview of the field, this book explains how to properly use signal processing techniques for biomedical applications and avoid misinterpretations and pitfalls. It helps readers to choose the appropriate method as well as design their own methods.

Biomedical Signals and Systems is meant to accompany a one-semester undergraduate signals and systems course. It may also serve as a quick-start for graduate students or faculty interested in how signals and systems techniques can be applied to living systems. The biological nature of the examples allows for systems thinking to be applied to electrical, mechanical, fluid, chemical, thermal and even optical systems. Each chapter focuses on a topic from classic signals and systems theory: System block diagrams, mathematical models, transforms, stability, feedback, system response, control, time and frequency analysis and filters. Embedded within each chapter are examples from the biological world, ranging from medical devices to cell and molecular biology. While the focus of the book is on the theory of analog signals and systems, many chapters also introduce the corresponding topics in the digital realm. Although some derivations appear, the focus is on the concepts and how to apply them. Throughout the text, systems vocabulary is introduced which will allow the reader to read more advanced literature and communicate with scientist and engineers. Homework and Matlab simulation exercises are presented at the end of each chapter and challenge readers to not only perform calculations and simulations but also to recognize the real-world signals and systems around them. Table of Contents: Preface / Acknowledgments / Introduction / System Types / System Models / Laplace Transform / Block Diagrams / Stability / Feedback / System Response / Control / Time Domain Analysis / Frequency Domain Analysis / Filters / Author's Biography

The use of digital signal processing is ubiquitous in the field of physiology and biomedical engineering. The application of such mathematical and computational tools requires a formal or explicit understanding of physiology. Formal models and analytical techniques are interlinked in physiology as in any other field. This book takes a unitary approach to physiological systems, beginning with signal measurement and acquisition, followed by signal processing, linear systems modelling, and computer simulations. The signal processing techniques range across filtering, spectral analysis and wavelet analysis. Emphasis is placed on fundamental understanding of the concepts as well as solving numerical problems. Graphs and analogies are used extensively to supplement the mathematics. Detailed models of nerve and muscle at the cellular and systemic levels provide examples for the mathematical methods and computer simulations. Several of the models are sufficiently sophisticated to be of value in understanding real world issues like neuromuscular disease. This second edition features expanded problem sets and a link to extra downloadable material.