This volume is a comprehensive guide to the diagnosis and treatment of benign and malignant tumors of the bone and soft tissues. Coverage includes: general issues in diagnosis, staging, surgery, radiation therapy, chemotherapy, and the psychological aspects of patient management. Focus is placed on benign bone tumors, malignant bone tumors, soft-tissue tumors, and carcinoma metastatic to bone. The sections on malignant bone tumors and carcinoma metastatic to bone include detailed guidelines for surgical treatment in each anatomic site. Special features include: considerations for management of malignant bone tumors in growing children; and discussions on the biology and complications of prosthetic and allograft reconstruction.

A systematic treatise of tumors and tumor-like lesions occurring in bone and soft tissues. The introductory chapter presents the terminology, the basic principles for classification and diagnosis, the general principles of imaging, biopsy and histology, the staging system and evaluation of the surgical margins, the general principles of curettage, local adjuvants, en bloc resection and reconstruction, chemotherapy and radiotherapy. Each pathologic entity is described according to its epidemiology, localization, symptoms, imaging, gross pathology, histopathology, histogenesis and pathogenesis, differential diagnosis, course and stage, treatment and prognosis.

Review of orthopaedic oncology with case presentations illustrating how each tumor would be diagnosed and managed in a clinical setting.

Bone and soft tissue sarcomas represent only about 2% of all malignancies; however, their treatment – with the goal of curing the patient while preserving the functionality of the affected body part – can, unlike other malignancies, only be successful with therapy concepts devised by interdisciplinary teams. This volume provides an extensive up-to-date overview of the specific diagnostics and current treatment standards of these rare entities, presenting the various limb-sparing modalities for patients with bone and soft tissue sarcomas with special regard to innovative reconstructive options. The evaluation of quality of life based on validated scores and the individual methods of coping with the illness through creative artistic projects are also acknowledged and integrated in the whole concept.

Steven A. Rosenberg, MD In the past two decades significant progress has quality of life. The use of local radiation therapy has occurred, in the management of patients with mus- had a profound impact on the ability to achieve local loskeletal cancers, that has improved both the survival control. Cooperation between surgeons and radiation and the quality of life of afflicted patients. Changes in therapists often results in the tailoring of surgical p- the management of these patients have mirrored cedures to maximize the combined application of these trends in the entire field of oncology. two effective treatment modalities. Although impact on The most significant change has been improvement overall survival has not been demonstrated due to the in the surgical techniques for the resection of musculo- addition of radiation therapy, important advances in skeletal cancers based on a detailed understanding of improving the quality of life of patients receiving this the anatomic features of each particular tumor site, as combined-modality treatment have been evident. well as an appreciation of the natural biology that affects A third change impacting on the survival of patients the local spread of these tumors. The current volume of with musculoskeletal cancers has been the aggressive Musculoskeletal Cancer Surgery: Treatment of Sarcomas and resection of metastatic deposits.

The “world” of soft tissue sarcomas is a highly complex one, due to the large range of tumor types, each of which is characterized by specific features in terms of its epidemiology, pathology diagnosis, clinical behavior, therapy and biomarker pattern (of both diagnostic and therapeutic value). This book offers a practical, clearly structured reference guide, covering all of these aspects for each soft tissue tumor. Thanks to the consistent and user-friendly format, readers can quickly and easily find the information they need; in addition, up-to-date and authoritative literature information helps them to pursue further research. Overall, this book offers professionals and residents in the fields of oncology, surgery, and pathology an essential guide for study, review, and everyday clinical practice.

This book reviews the latest techniques for diagnostics and treatments specific to bone and soft tissue tumors. It focuses on imaging and classification of the bone and soft tissue tumors and how histology and cytogenetic aspects can be used to identify tumors. Each chapter focuses on a specific type of tumor, providing a concise overview of relevant information on their characteristics along with the latest surgical and medical treatments available. Bone Tumors: Diagnosis and Therapy Today is a concise guide to successfully identifying and treating bone and soft tissue tumors, making it a valuable resource for practicing medical professionals and trainees who encounter these patients in their day-to-day practice.