Almost 30 years after the first reports on surface-enhanced Raman signals, the phenomenon of surface-enhanced Raman scattering (SERS) is now well established. SERS gained particular interest after single-molecule Raman spectroscopy had been demonstrated. This book summarizes and discusses present theoretical approaches that explain the phenomenon of SERS and reports on new and exciting experiments and applications of the fascinating spectroscopic effect.

Covering everything from the basic theoretical and practical knowledge to new exciting developments in the field with a focus on analytical and life science applications, this monograph shows how to apply surface-enhanced Raman scattering (SERS) for solving real world problems. From the contents: * Theory and practice of SERS * Analytical applications * SERS combined with other analytical techniques * Biophysical applications * Life science applications including various microscopies Aimed at analytical, surface and medicinal chemists, spectroscopists, biophysicists and materials scientists. Includes a Foreword by the renowned Raman spectroscopist Professor Wolfgang Kiefer, the former Editor-in-Chief of the Journal of Raman Spectroscopy.

This book discusses the recent advances in the area of near-field Raman scattering, mainly focusing on tip-enhanced and surface-enhanced Raman scattering. Some of the key features covered here are the optical structuring and manipulations, single molecule sensitivity, analysis of single-walled carbon nanotubes, and analytic applications in chemistry, biology and material sciences. This book also discusses the plasmonic materials for better enhancement, and optical antennas. Further, near-field microscopy based on second harmonic generation is also discussed. Chapters have been written by some of the leading scientists in this field, who present some of their recent work in this field.·Near-field Raman scattering·Tip-enhanced Raman spectroscopy·Surface-enhanced Raman spectroscopy·Nano-photonics·Nanoanalysis of Physical, chemical and biological materials beyond the diffraction limits·Single molecule detection

In the last decade, we have seen spurring growth in academic and industrial interest in Raman spectroscopy and its modifications, in particular, Surface-Enhanced Raman Spectroscopy (SERS). This is evident by the number of SERS publications in the last decade, from 580 in 2005 to almost 2000 in 2014. There are now companies worldwide that are dedicated to manufacturing SERS substrate, sensors, and other SERS-based products. The miniaturization of Raman instrumentation from bulky and expensive bench-top designs to inexpensive handheld spectrometers has allowed SERS to be employed as an in situ detection technique. Some examples of the industrial success of Raman and SERS are rapid raw material identification (RMID), Process Analytical Technology (PAT) and drug screening in pharma and biotech industries, continuous surveillance of food, water, and environmental safety, and the diagnosis and continuous monitoring of diseases like cancer, diabetes, etc. This progress in translating Raman and SERS techniques into commercial use and commercial products is possible because of the close collaboration between scientists and engineers. However, the weak signals of Raman spectroscopy is an inherent limitation of the spontaneous Raman spectroscopy technique. Therefore, several modifications have been made, including but not limited to, surface-enhanced Raman spectroscopy (SERS), spatially offset Raman spectroscopy (SORS), transmission Raman spectroscopy (TRS), coherent anti-Stokes Raman spectroscopy (CARS), and tip-enhanced Raman spectroscopy (TERS). Spontaneous Raman spectroscopy has become a one-of-a kind, portable, and affordable technology for in-situ detection and continuous monitoring in resource-limited-settings. The primary focus of this textbook is to try to cover the fundamentals in SERS methods of preparing substrates and sensors, and efficient spectral analysis approaches like chemometrics for diverse applications, listed in the paragraph above. However, with a goal to give a true picture to the audience when assessing the scope of spontaneous Raman and Surface-enhanced Raman for specific applications, we have briefly introduced industrially successful examples of other types of Raman spectroscopy techniques, such as SORS, TRS, and CARS.

Surface-Enhanced Raman Spectroscopy: Principles, Experiments, and Applications is a comprehensive, up to date, and balanced treatment of the theoretical and practical aspects of Surface-Enhanced Raman Scattering (SERS), a useful branch of spectroscopy for several areas of science. This book describes the basic principles of SERS, including SERS mechanisms, performing SERS measurements, and interpreting data. Also emphasized are applications in electrochemistry; catalysis; surface processing and corrosion; Self-Assemble-Layer and L-B Films; polymer science; biology; medicine and drug analysis; sensors; fuel cells; forensics; and archaeology. It is an essential guide for student and professional analytical chemists.

Surface Enhanced Vibrational Spectroscopy (SEVS) has reached maturity as an analytical technique, but until now there has been no single work that describes the theory and experiments of SEVS. This book combines the two important techniques of surface-enhanced Raman scattering (SERS) and surface-enhanced infrared (SEIR) into one text that serves as the definitive resource on SEVS. Discusses both the theory and the applications of SEVS and provides an up-to-date study of the state of the art Offers interpretations of SEVS spectra for practicing analysts Discusses interpretation of SEVS spectra, which can often be very different to the non-enhanced spectrum - aids the practicing analyst