Henry Ledbetter was probably born in England in about 1625. He probably emigrated as a child and settled in Virginia. He married and had about eight children. He died before 1700 in Charles City County, Virginia. Descendants and relatives lived mainly in Virginia, North Carolina, Alabama, Georgia, Illinois, Tennessee, Missouri and Texas.

Allied families were Baldwin, Bridges, Comer, Daniel, Furcron, Jennings, Jones, Lacy, Neel, Quillian, Russell, Smith, Tiller, Whipple, and others.

John Wooldridge was born in about 1678. He married Martha and they had six children. He died in 1757. Descendants and relatives lived mainly in Virginia, West Virginia, Kentucky, Tennessee, Georgia, Missouri, Kansas, Mississippi, Arkansas, Louisiana, Oklahoma, Texas and Oregon.

John Manning? Cain (1779-1876) was either born in Rutherford Co., N. C. or near Richmond, Va. He was buried in Gwinnett Co., Ga. He married Harriet Malinda (Milly?) Prickett/Pritchard in 1804 and they had five children. In 1825, he married Edna Poole (1783-ca. 1856) and they had one son. All the families of this book were intermarried. Descendants and relatives lived chiefly in the South.