A comprehensive introduction to modern applied statistical genetic data analysis, accessible to those without a background in molecular biology or genetics. Human genetic research is now relevant beyond biology, epidemiology, and the medical sciences, with applications in such fields as psychology, psychiatry, statistics, demography, sociology, and economics. With advances in computing power, the availability of data, and new techniques, it is now possible to integrate large-scale molecular genetic information into research across a broad range of topics. This book offers the first comprehensive introduction to modern applied statistical genetic data analysis that covers theory, data preparation, and analysis of molecular genetic data, with hands-on computer exercises. It is accessible to students and researchers in any empirically oriented medical, biological, or social science discipline; a background in molecular biology or genetics is not required. The book first provides foundations for statistical genetic data analysis, including a survey of fundamental concepts, primers on statistics and human evolution, and an introduction to polygenic scores. It then covers the practicalities of working with genetic data, discussing such topics as analytical challenges and data management. Finally, the book presents applications and advanced topics, including polygenic score and gene-environment interaction applications, Mendelian Randomization and instrumental variables, and ethical issues. The software and data used in the book are freely available and can be found on the book's website.

Statistical modeling is a critical tool in scientific research. This book provides comprehensive explanations of the concepts and philosophy of statistical modeling, together with a wide range of practical and numerical examples. The authors expect this work to be of great value not just to statisticians but also to researchers and practitioners in various fields of research such as information science, computer science, engineering, bioinformatics, economics, marketing and environmental science. It’s a crucial area of study, as statistical models are used to understand phenomena with uncertainty and to determine the structure of complex systems. They’re also used to control such systems, as well as to make reliable predictions in various natural and social science fields.

This is the first comprehensive, yet clearly presented, account of statistical methods for analysing spherical data. The analysis of data, in the form of directions in space or of positions of points on a spherical surface, is required in many contexts in the earth sciences, astrophysics and other fields, yet the methodology required is disseminated throughout the literature. Statistical Analysis of Spherical Data aims to present a unified and up-to-date account of these methods for practical use. The emphasis is on applications rather than theory, with the statistical methods being illustrated throughout the book by data examples.

This broad text provides a complete overview of most standard statistical methods, including multiple regression, analysis of variance, experimental design, and sampling techniques. Assuming a background of only two years of high school algebra, this book teaches intelligent data analysis and covers the principles of good data collection. * Provides a complete discussion of analysis of data including estimation, diagnostics, and remedial actions * Examples contain graphical illustration for ease of interpretation * Intended for use with almost any statistical software * Examples are worked to a logical conclusion, including interpretation of results * A complete Instructor's Manual is available to adopters

This book is a guide to the practical application of statistics in data analysis as typically encountered in the physical sciences. It is primarily addressed at students and professionals who need to draw quantitative conclusions from experimental data. Although most of the examples are takenfrom particle physics, the material is presented in a sufficiently general way as to be useful to people from most branches of the physical sciences. The first part of the book describes the basic tools of data analysis: concepts of probability and random variables, Monte Carlo techniques,statistical tests, and methods of parameter estimation. The last three chapters are somewhat more specialized than those preceding, covering interval estimation, characteristic functions, and the problem of correcting distributions for the effects of measurement errors (unfolding).

For most of us, "painless" is not the word that comes to mind when we think of statistics, but author and educator Liwen Vaughan wants to change that. In this unique and useful book, Vaughan clearly explains the statistical methods used in information science research, focusing on basic logic rather than mathematical intricacies. Her emphasis is on the meaning of statistics, when and how to apply them, and how to interpret the results of statistical analysis. Through the use of real-world examples, she shows how statistics can be used to improve services, make better decisions, and conduct more effective research. Whether you are doing statistical analysis or simply need to better understand the statistics you encounter in professional literature and the media, this book will be a valuable addition to your personal toolkit. Includes more than 80 helpful figures and tables, 7 appendices, bibliography, index.

This book is a collection of essays on the foundations of Statistical Inference. The sequence in which the essays have been arranged makes it possible to read the book as a single contemporay discourse on the likelihood principle, the paradoxes that attend its violation, and the radical deviation from classical statistical practices that its adoption would entail. The book can also be read, with the aid of the notes as a chronicle of the development of Basu's ideas.