A pandemic raging across Alpha Centauri. A powerful enemy aboard the Enterprise. With death lurking around every corner, the crew will face down one of their greatest challenges yet in the shocking concludion to this episode from Eisner-winning writer Jim McCann (Return of the Dapper Men) and superstar artist Angel Hernandez (Star Trek: Picard)!

Join the crew of the U.S.S Enterprise in all-new adventures as they near the end of their five-year mission, featuring the characters from the Original Series! The crew of the Enterprise left Earth four years ago. They've traveled to strange new worlds, defeated impossible foes, and made universe-changing decisions. But now, with the end in sight, they'll have to face their biggest challenge yet. Step aboard the Enterprise with Kirk, Spock, Bones, Uhura, Sulu, Scotty, and Chekov as they begin the end of their original five-year mission and boldly go into an uncertain future in this new continuing Star Trek series! Collects issues #1–6.

As a fleet of Tholian vessels closes in, Kirk and the rest of the crew struggle to free the Enterprise from the Tholian Web before it’s too late. And with the destruction of the ship hanging in the balance, Bright Eyes will have to make a choice between their human friends or going home. The final voyages of the original mission continue here!

Join the crew of the original Starship Enterprise in these all-new adventures near the end of their five-year mission. The Enterprise and her crew finally make it back to Federation space, but the Federation they find isn't quite the same as the one they had left behind! Kirk grapples with a very personal Klingon threat, even as the Enterprise begins its homecoming victory tour, and the Federation's upcoming presidential election is upended when Harry Mudd enters the race! All this against the backdrop of a sinister malaise threatening to rot the Federation from within. Terrible secrets are revealed, among them the origin of Gary Seven and the grand designs of the shadowy AEGIS organization. Can Kirk and the Enterprise crew excise this corruption, or will the five-year mission end in failure? Collects issues #13-19 of the ongoing series by writers Jackson Lanzing, Collin Kelly, Jody Houser, and Jim McCann with artists Angel Hernandez, Silvia Califano, and J.K. Woodward.

The thrilling adventure based on the acclaimed Star Trek: Picard TV series! Starfleet was everything for Cristóbal Rios…until one horrible, inexplicable day when it all went wrong. Aimless and adrift, he grasps at a chance for a future as an independent freighter captain in an area betrayed by the Federation, the border region with the former Romulan Empire. His greatest desire: to be left alone. But solitude isn’t in the cards for the captain of La Sirena, who falls into debt to a roving gang of hoodlums from a planet whose society is based on Prohibition-era Earth. Teamed against his will with Ledger, his conniving overseer, Rios begins an odyssey that brings him into conflict with outlaws and fortune seekers, with power brokers and relic hunters across the stars. Exotic loves and locales await—as well as dangers galore—and Rios learns the hard way that good crewmembers are hard to find, even when you can create your own. And while his meeting with Jean-Luc Picard is years away, Rios finds himself drawing on the Starfleet legend’s experiences when he discovers a mystery that began on one of the galaxy’s most important days…. ​™, ®, & © 2021 CBS Studios, Inc. STAR TREK and related marks and logos are trademarks of CBS Studios, Inc. All Rights Reserved.

With Captain Kirk still incapacitated, Spock finds himself trapped between a planet quickly spinning into chaos and a crew at each other's throats. The end of the original mission is in sight... if the Enterprise can make it out in one piece.

The Enterprise receives a distress call from Alpha Centauri and arrives to find a planet in the midst of a deadly global pandemic. But is nature responsible for this new virus, or is there something more sinister at play? The final voyages of the U.S.S. Enterprise continue in this new episode from Eisner-winning writer Jim McCann (Return of the Dapper Men) and superstar artist Angel Hernandez (Star Trek: Picard)!